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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 2
2006 2
2007 2
2008 7
2009 9
2010 6
2011 16
2012 14
2013 25
2014 21
2015 24
2016 36
2017 30
2018 28
2019 32
2020 49
2021 59
2022 32
2023 37
2024 11

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380 results

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How the Warburg effect supports aggressiveness and drug resistance of cancer cells?
Icard P, Shulman S, Farhat D, Steyaert JM, Alifano M, Lincet H. Icard P, et al. Drug Resist Updat. 2018 May;38:1-11. doi: 10.1016/j.drup.2018.03.001. Epub 2018 Mar 20. Drug Resist Updat. 2018. PMID: 29857814 Review.
However, their proliferation is marked by a shift towards increasing glycolytic metabolism even in the presence of O(2) (Warburg effect). HIF1, a major hypoxia induced transcription factor, promotes a dissociation between glycolysis and the tricarboxylic acid cycle, …
However, their proliferation is marked by a shift towards increasing glycolytic metabolism even in the presence of O(2) (Warburg e …
Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.
Luo P, Zhang Q, Zhong TY, Chen JY, Zhang JZ, Tian Y, Zheng LH, Yang F, Dai LY, Zou C, Li ZJ, Liu JH, Wang JG. Luo P, et al. Mil Med Res. 2022 May 20;9(1):22. doi: 10.1186/s40779-022-00381-4. Mil Med Res. 2022. PMID: 35596191 Free PMC article.
Cel bound to Cys424 of pyruvate kinase M2 (PKM2), inhibiting the enzyme and thereby suppressing aerobic glycolysis (Warburg effect). Cel also bound to Cys106 in high mobility group box 1 (HMGB1) protein, reducing the secretion of inflammatory cytokine interleukin (I …
Cel bound to Cys424 of pyruvate kinase M2 (PKM2), inhibiting the enzyme and thereby suppressing aerobic glycolysis (Warburg effect …
The Potential Health Benefits of the Ketogenic Diet: A Narrative Review.
Dowis K, Banga S. Dowis K, et al. Nutrients. 2021 May 13;13(5):1654. doi: 10.3390/nu13051654. Nutrients. 2021. PMID: 34068325 Free PMC article. Review.
The evidence also suggests that eating a high-fat diet improves lipid profiles by lowering low-density lipoprotein (LDL), increasing high-density lipoprotein (HDL), and lowering triglycerides (TG). Due to the Warburg effect, the KD is used as an adjuvant treatment t …
The evidence also suggests that eating a high-fat diet improves lipid profiles by lowering low-density lipoprotein (LDL), increasing high-de …
Insulin-Like Growth Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer.
Kasprzak A. Kasprzak A. Int J Mol Sci. 2021 Jun 16;22(12):6434. doi: 10.3390/ijms22126434. Int J Mol Sci. 2021. PMID: 34208601 Free PMC article. Review.
However, the underlying mechanisms linking IGF-1 and MetS are still poorly understood. Hyperactivated glucose uptake and aerobic glycolysis (the Warburg effect) are considered as a one of six hallmarks of cancer, including CRC. ...This review describes the role of I …
However, the underlying mechanisms linking IGF-1 and MetS are still poorly understood. Hyperactivated glucose uptake and aerobic glycolysis …
Metabolic reprogramming: the emerging concept and associated therapeutic strategies.
Yoshida GJ. Yoshida GJ. J Exp Clin Cancer Res. 2015 Oct 6;34:111. doi: 10.1186/s13046-015-0221-y. J Exp Clin Cancer Res. 2015. PMID: 26445347 Free PMC article. Review.
Metabolic reprogramming is required for both malignant transformation and tumor development, including invasion and metastasis. Although the Warburg effect has been widely accepted as a common feature of metabolic reprogramming, accumulating evidence has revealed th …
Metabolic reprogramming is required for both malignant transformation and tumor development, including invasion and metastasis. Although the …
Ketogenic Diet for Cancer: Critical Assessment and Research Recommendations.
Lane J, Brown NI, Williams S, Plaisance EP, Fontaine KR. Lane J, et al. Nutrients. 2021 Oct 12;13(10):3562. doi: 10.3390/nu13103562. Nutrients. 2021. PMID: 34684564 Free PMC article. Review.
The mechanisms underlying the hypothesized effects of KD, most notably the Warburg Effect, suggest that restricting carbohydrate content may impede cancer development and progression via several pathways (e.g., tumor metabolism, gene expression). ...We propose a set …
The mechanisms underlying the hypothesized effects of KD, most notably the Warburg Effect, suggest that restricting carbohydra …
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.
Kornberg MD, Bhargava P, Kim PM, Putluri V, Snowman AM, Putluri N, Calabresi PA, Snyder SH. Kornberg MD, et al. Science. 2018 Apr 27;360(6387):449-453. doi: 10.1126/science.aan4665. Epub 2018 Mar 29. Science. 2018. PMID: 29599194 Free PMC article.
Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a potential therapeutic target in autoimmune disease. ...
Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a poten …
Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy.
Abdel-Wahab AF, Mahmoud W, Al-Harizy RM. Abdel-Wahab AF, et al. Pharmacol Res. 2019 Dec;150:104511. doi: 10.1016/j.phrs.2019.104511. Epub 2019 Oct 31. Pharmacol Res. 2019. PMID: 31678210 Review.
Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which is a hallmark of cancer. The altered energy metabolism not only provides cancer cell …
Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely on aerobic glycolysis for energy production, a phe …
380 results