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Page 1
The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.
Stoyanova T, Yoon T, Kopanja D, Mokyr MB, Raychaudhuri P. Stoyanova T, et al. Mol Cell Biol. 2008 Jan;28(1):177-87. doi: 10.1128/MCB.00880-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967871 Free PMC article.
The xeroderma pigmentosum group E gene product DDB2, a protein involved in nucleotide excision repair (NER), associates with the E3 ubiquitin ligase complex Cul4A-DDB1. ...
The xeroderma pigmentosum group E gene product DDB2, a protein involved in nucleotide excision repair (NER), ass …
Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair.
Hwang BJ, Ford JM, Hanawalt PC, Chu G. Hwang BJ, et al. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):424-8. doi: 10.1073/pnas.96.2.424. Proc Natl Acad Sci U S A. 1999. PMID: 9892649 Free PMC article.
The p48 gene is required for expression of an ultraviolet radiation-damaged DNA binding activity and is disrupted by mutations in the subset of xeroderma pigmentosum group E cells that lack this activity. Here, we show that p48 mRNA levels strongly dep …
The p48 gene is required for expression of an ultraviolet radiation-damaged DNA binding activity and is disrupted by mutations in the subset …
p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice.
Tan T, Chu G. Tan T, et al. Mol Cell Biol. 2002 May;22(10):3247-54. doi: 10.1128/MCB.22.10.3247-3254.2002. Mol Cell Biol. 2002. PMID: 11971958 Free PMC article.
The DDB2 gene, which is mutated in xeroderma pigmentosum group E, enhances global genomic repair of cyclobutane pyrimidine dimers and suppresses UV-induced mutagenesis. ...
The DDB2 gene, which is mutated in xeroderma pigmentosum group E, enhances global genomic repair of cyclobutane …
Mutations specific to the xeroderma pigmentosum group E Ddb- phenotype.
Nichols AF, Ong P, Linn S. Nichols AF, et al. J Biol Chem. 1996 Oct 4;271(40):24317-20. doi: 10.1074/jbc.271.40.24317. J Biol Chem. 1996. PMID: 8798680 Free article.
The activity of a damage-specific DNA-binding protein (DDB) is absent from a subset, Ddb-, of cell strains from patients with xeroderma pigmentosum group E (XP-E). DDB is a heterodimer of 127-kDa and 48-kDa subunits. ...
The activity of a damage-specific DNA-binding protein (DDB) is absent from a subset, Ddb-, of cell strains from patients with xeroderma
45 results