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Quoted phrase not found in phrase index: "Yolk Sac Tumor with Somatic-Type Malignancy"
Page 1
Somatic-type malignancies in testicular germ cell tumors.
Guo CC, Czerniak B. Guo CC, et al. Hum Pathol. 2022 Sep;127:123-135. doi: 10.1016/j.humpath.2022.06.024. Epub 2022 Jul 5. Hum Pathol. 2022. PMID: 35803413 Review.
Most SMs are derived from teratoma, and the remainder is associated with yolk sac tumor. They occur more frequently in metastases than in primary testicular tumors. ...Furthermore, somatic-type carcinoma is likely associated with a worse prog …
Most SMs are derived from teratoma, and the remainder is associated with yolk sac tumor. They occur more frequently in …
Reprint of: somatic-type malignancies in testicular germ cell tumors.
Guo CC, Czerniak B. Guo CC, et al. Hum Pathol. 2023 Mar;133:102-114. doi: 10.1016/j.humpath.2023.02.008. Epub 2023 Mar 6. Hum Pathol. 2023. PMID: 36890027 Review.
Most SMs are derived from teratoma, and the remainder is associated with yolk sac tumor. They occur more frequently in metastases than in primary testicular tumors. ...Furthermore, somatic-type carcinoma is likely associated with a worse prog …
Most SMs are derived from teratoma, and the remainder is associated with yolk sac tumor. They occur more frequently in …
Sarcomatoid Yolk Sac Tumor Harbors Somatic Mutations That Are Otherwise Rare in Testicular Germ Cell Tumors.
Acosta AM, Al-Obaidy KI, Sholl LM, Dickson BC, Lindeman NI, Hirsch MS, Collins K, Fletcher CD, Idrees MT. Acosta AM, et al. Am J Surg Pathol. 2022 May 1;46(5):701-712. doi: 10.1097/PAS.0000000000001865. Am J Surg Pathol. 2022. PMID: 35034041
In testicular germ cell tumors (TGCTs), components with nonspecific sarcomatous features that express keratins and glypican 3 are classified as sarcomatoid yolk sac tumor (SYST). SYST is most frequently seen in metastatic sites after chemotherapy. Like so-cal …
In testicular germ cell tumors (TGCTs), components with nonspecific sarcomatous features that express keratins and glypican 3 are classified …
Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets.
Bremmer F, Pongratanakul P, Skowron M, Che Y, Richter A, Küffer S, Reuter-Jessen K, Bohnenberger H, Pauls S, Kresbach C, Schüller U, Stühler K, Ströbel P, Albers P, Nettersheim D. Bremmer F, et al. Br J Cancer. 2023 Nov;129(10):1580-1589. doi: 10.1038/s41416-023-02425-5. Epub 2023 Sep 19. Br J Cancer. 2023. PMID: 37726478 Free PMC article.
BACKGROUND: Germ cell tumors (GCT) might undergo transformation into a somatic-type malignancy (STM), resulting in a cell fate switch to tumors usually found in somatic tissues, such as rhabdomyosarcomas or adenocarcinomas. ...RESULTS AND CONCLUSIONS: For the first …
BACKGROUND: Germ cell tumors (GCT) might undergo transformation into a somatic-type malignancy (STM), resulting in a cell fate …
Age-incidence patterns of seminoma and nonseminoma among males and females in Germany and the United States, 2008-2016.
Stang A, Trocchi P, Kajüter H, Trabert B, Oosterhuis JW, McGlynn KA. Stang A, et al. Andrology. 2023 Jan;11(1):65-72. doi: 10.1111/andr.13282. Epub 2022 Sep 12. Andrology. 2023. PMID: 36059277 Free article.
The three most common testicular germ cell tumors histologies were seminoma, mixed germ cell tumors, and embryonal carcinoma Among females, the three most common ovarian germ cell tumors histologies were teratoma, yolk sac tumor, monodermal teratomas, and …
The three most common testicular germ cell tumors histologies were seminoma, mixed germ cell tumors, and embryonal carcinoma Among females, …
Unresectable Metastatic Testicular Germ Cell Tumor With Low-grade Neuroglial Neoplasm, Stable After Radiation and Chemotherapy.
Tabibi S, Kamanda S, Llosa N, Pratilas CA, Duncan BB, Esteves RS, Matoso A. Tabibi S, et al. Appl Immunohistochem Mol Morphol. 2023 Jan 1;31(1):47-50. doi: 10.1097/PAI.0000000000001081. Epub 2022 Oct 26. Appl Immunohistochem Mol Morphol. 2023. PMID: 36476600 Free PMC article.
Histologic and immunohistochemical examinations revealed an embryonic type neuroectodermal tumor (somatic-type malignancy, 10%) arising in a malignant mixed germ cell tumor composed of teratoma (50%), embryonal carcinoma (10%) and yolk …
Histologic and immunohistochemical examinations revealed an embryonic type neuroectodermal tumor (somatic-type malignan …
Management of germ cell tumors with somatic type malignancy: pathological features, prognostic factors and survival outcomes.
Rice KR, Magers MJ, Beck SD, Cary KC, Einhorn LH, Ulbright TM, Foster RS. Rice KR, et al. J Urol. 2014 Nov;192(5):1403-9. doi: 10.1016/j.juro.2014.05.118. Epub 2014 Jun 18. J Urol. 2014. PMID: 24952240
RESULTS: A total of 121 patients met the study inclusion criteria. The most common somatic type malignancy histologies were sarcoma (59), carcinoma (31) and sarcomatoid yolk sac tumor (17). ...Established prognostic factors for germ cell …
RESULTS: A total of 121 patients met the study inclusion criteria. The most common somatic type malignancy histologies were sa …
Pathology and molecular biology of teratomas in childhood and adolescence.
Harms D, Zahn S, Göbel U, Schneider DT. Harms D, et al. Klin Padiatr. 2006 Nov-Dec;218(6):296-302. doi: 10.1055/s-2006-942271. Klin Padiatr. 2006. PMID: 17080330
Only 7.8 % of all teratomas show the highest grade of immaturity (G3). The frequency of additional microscopic foci of malignant yolk sac tumor correlates with the grade of immaturity. In sacrococcygeal teratomas, the yolk sac tumor …
Only 7.8 % of all teratomas show the highest grade of immaturity (G3). The frequency of additional microscopic foci of malignant y …
"Somatic-type" malignancies arising from testicular germ cell tumors: a clinicopathologic study of 124 cases with emphasis on glandular tumors supporting frequent yolk sac tumor origin.
Magers MJ, Kao CS, Cole CD, Rice KR, Foster RS, Einhorn LH, Ulbright TM. Magers MJ, et al. Am J Surg Pathol. 2014 Oct;38(10):1396-409. doi: 10.1097/PAS.0000000000000262. Am J Surg Pathol. 2014. PMID: 24921638
Somatic-type malignancies (SMs) in patients with testicular germ cell tumors (GCT) are rare and mostly attributed to "transformation" of teratoma, although yolk sac tumor (YST) origin has also been proposed. ...
Somatic-type malignancies (SMs) in patients with testicular germ cell tumors (GCT) are rare and mostly attributed to "t …
Fluorescent In Situ Hybridization Analysis for 12p Alterations in Sarcomatoid Yolk Sac Tumors.
Idrees MT, Ulbright TM, Epstein JI. Idrees MT, et al. Am J Surg Pathol. 2019 Nov;43(11):1566-1573. doi: 10.1097/PAS.0000000000001354. Am J Surg Pathol. 2019. PMID: 31478941
"Sarcomas" in patients with testicular germ cell tumors (GCTs) are a common form of "somatic-type malignancy." There is support, based on morphology and immunohistochemistry, that many such sarcomatous tumors represent an unusual form of yolk sac tu …
"Sarcomas" in patients with testicular germ cell tumors (GCTs) are a common form of "somatic-type malignancy." There is suppor …
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