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Palonosetron.
[No authors listed] [No authors listed] 2021 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 33630479 Free Books & Documents. Review.
No information is available on the use of palonosetron during breastfeeding. Until more data become available, palonosetron should be used with caution during breastfeeding. ...
No information is available on the use of palonosetron during breastfeeding. Until more data become available, palonosetron sh …
Palonosetron.
Siddiqui MA, Scott LJ. Siddiqui MA, et al. Drugs. 2004;64(10):1125-32; discussion 1133-4. doi: 10.2165/00003495-200464100-00006. Drugs. 2004. PMID: 15139789 Review.
Intravenous palonosetron was generally well tolerated in clinical trials, with few adverse events being treatment related. Palonosetron had no significant effect on the corrected QT interval or laboratory parameters....
Intravenous palonosetron was generally well tolerated in clinical trials, with few adverse events being treatment related. Palonos
Netupitant/Palonosetron: A Review in Chemotherapy-Induced Nausea and Vomiting.
Shirley M. Shirley M. Drugs. 2021 Jul;81(11):1331-1342. doi: 10.1007/s40265-021-01558-2. Epub 2021 Jul 22. Drugs. 2021. PMID: 34292534 Free PMC article. Review.
Netupitant/palonosetron (NEPA; Akynzeo()), available in oral and intravenous (IV) formulations, is a fixed-dose combination of the neurokinin 1 (NK1) receptor antagonist netupitant (or the prodrug, fosnetupitant, in the IV formulation) and the second-generation serotonin 3 …
Netupitant/palonosetron (NEPA; Akynzeo()), available in oral and intravenous (IV) formulations, is a fixed-dose combination of the ne …
Palonosetron for Patients Undergoing High or Moderate Emetogenic Chemotherapy.
Tran K, Loshak H. Tran K, et al. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2021 Jul. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2021 Jul. PMID: 36191121 Free Books & Documents. Review.
Oral palonosetron is indicated in adults for the prevention of acute nausea and vomiting associated with MEC". ...Both dosage forms of palonosetron (IV and oral) were reviewed by the CADTH Common Drug Review in 2012.(-) The combination product palonosetron-ne …
Oral palonosetron is indicated in adults for the prevention of acute nausea and vomiting associated with MEC". ...Both dosage forms o …
Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice.
Aapro M, Jordan K, Scotté F, Celio L, Karthaus M, Roeland E. Aapro M, et al. Curr Cancer Drug Targets. 2022;22(10):806-824. doi: 10.2174/1568009622666220513094352. Curr Cancer Drug Targets. 2022. PMID: 35570542 Free PMC article. Review.
NEPA is the first and only fixed combination antiemetic, composed of netupitant (oral)/fosnetupitant (intravenous) and palonosetron, which, together with dexamethasone, constitute a triple antiemetic combination recommended for the prevention of CINV for patients receiving …
NEPA is the first and only fixed combination antiemetic, composed of netupitant (oral)/fosnetupitant (intravenous) and palonosetron, …
Netupitant/Palonosetron: A Review in the Prevention of Chemotherapy-Induced Nausea and Vomiting.
Keating GM. Keating GM. Drugs. 2015 Dec;75(18):2131-41. doi: 10.1007/s40265-015-0512-9. Drugs. 2015. PMID: 26613606 Review.
Complete response rates during the delayed, acute and overall phases were significantly higher with single-dose netupitant 300 mg plus palonosetron 0.5 mg than with single-dose palonosetron 0.5 mg in cycle 1 of cisplatin-based highly emetogenic chemotherapy (HEC) in …
Complete response rates during the delayed, acute and overall phases were significantly higher with single-dose netupitant 300 mg plus pa
Palonosetron for the treatment of chemotherapy-induced nausea and vomiting.
Navari RM. Navari RM. Expert Opin Pharmacother. 2014 Dec;15(17):2599-608. doi: 10.1517/14656566.2014.972366. Epub 2014 Oct 17. Expert Opin Pharmacother. 2014. PMID: 25323946 Review.
EXPERT OPINION: The clinical data in the literature have established palonosetron as the 5-HT3 receptor antagonist of choice in terms of efficacy and safety for the prevention of CINV for patients receiving moderately or highly emetogenic chemotherapy. Three international …
EXPERT OPINION: The clinical data in the literature have established palonosetron as the 5-HT3 receptor antagonist of choice in terms …
Palonosetron: in the prevention of nausea and vomiting.
Yang LP, Scott LJ. Yang LP, et al. Drugs. 2009 Nov 12;69(16):2257-78. doi: 10.2165/11200980-000000000-00000. Drugs. 2009. PMID: 19852528 Review.
Oral palonosetron was noninferior to intravenous palonosetron in preventing CINV in the acute phase in patients receiving MEC. ...Intravenous palonosetron is a useful alternative to currently recommended agents in PONV prevention....
Oral palonosetron was noninferior to intravenous palonosetron in preventing CINV in the acute phase in patients receiving MEC. …
Efficacy of palonosetron in postoperative nausea and vomiting (PONV)-a meta-analysis.
Singh PM, Borle A, Gouda D, Makkar JK, Arora MK, Trikha A, Sinha A, Goudra B. Singh PM, et al. J Clin Anesth. 2016 Nov;34:459-82. doi: 10.1016/j.jclinane.2016.05.018. Epub 2016 Jun 28. J Clin Anesth. 2016. PMID: 27687434 Review.
Palonosetron demonstrated statistical superiority over placebo for VI and CR, both early/delayed PONV prevention. ...In early phase, palonosetron had better VI and CR than did granisetron; however, variables other than CR (better for palonosetron) failed to a
Palonosetron demonstrated statistical superiority over placebo for VI and CR, both early/delayed PONV prevention. ...In early phase,
Palonosetron for the prevention of chemotherapy-induced nausea and vomiting.
Mori-Vogt S, Blazer M. Mori-Vogt S, et al. Expert Rev Anticancer Ther. 2013 Aug;13(8):919-36. doi: 10.1586/14737140.2013.814412. Expert Rev Anticancer Ther. 2013. PMID: 23984894 Review.
The class of medications known as serotonin receptor antagonists (5-HT3RAs) are integral in the prevention of CINV from both moderately and highly emetogenic chemotherapy. Palonosetron (ALOXI()), a second-generation 5-HT3RA, has a higher affinity for the 5-HT3 receptor, ha …
The class of medications known as serotonin receptor antagonists (5-HT3RAs) are integral in the prevention of CINV from both moderately and …
866 results