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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1995 6
1996 4
1997 7
1998 12
1999 14
2000 12
2001 9
2002 10
2003 9
2004 11
2005 8
2006 16
2007 13
2008 13
2009 8
2010 10
2011 8
2012 8
2013 6
2014 12
2015 7
2016 8
2017 5
2018 7
2019 9
2020 6
2021 11
2022 5
2023 3
2024 0

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239 results

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Page 1
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Surka C, Jin L, Mbong N, Lu CC, Jang IS, Rychak E, Mendy D, Clayton T, Tindall E, Hsu C, Fontanillo C, Tran E, Contreras A, Ng SWK, Matyskiela M, Wang K, Chamberlain P, Cathers B, Carmichael J, Hansen J, Wang JCY, Minden MD, Fan J, Pierce DW, Pourdehnad M, Rolfe M, Lopez-Girona A, Dick JE, Lu G. Surka C, et al. Blood. 2021 Feb 4;137(5):661-677. doi: 10.1182/blood.2020008676. Blood. 2021. PMID: 33197925 Free PMC article.
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP. Matyskiela ME, et al. Nature. 2016 Jul 14;535(7611):252-7. doi: 10.1038/nature18611. Epub 2016 Jun 22. Nature. 2016. PMID: 27338790
Polypeptide chain release factors.
Buckingham RH, Grentzmann G, Kisselev L. Buckingham RH, et al. Mol Microbiol. 1997 May;24(3):449-56. doi: 10.1046/j.1365-2958.1997.3711734.x. Mol Microbiol. 1997. PMID: 9179839 Free article. Review.
Translational termination comes of age.
Kisselev LL, Buckingham RH. Kisselev LL, et al. Trends Biochem Sci. 2000 Nov;25(11):561-6. doi: 10.1016/s0968-0004(00)01669-8. Trends Biochem Sci. 2000. PMID: 11084369 Review.
239 results