"rho-Associated Kinases*"[MeSH Major Topic] - Search Results

Year	Number of Results
2003	1
2004	2
2005	3
2006	12
2007	60
2008	225
2009	213
2010	243
2011	261
2012	250
2013	286
2014	289
2015	300
2016	282
2017	247
2018	222
2019	250
2020	233
2021	170
2022	84
2023	36
2024	31

1

ROCK2 Inhibition With Belumosudil (KD025) for the Treatment of Chronic Graft-Versus-Host Disease.

Jagasia M, Lazaryan A, Bachier CR, Salhotra A, Weisdorf DJ, Zoghi B, Essell J, Green L, Schueller O, Patel J, Zanin-Zhorov A, Weiss JM, Yang Z, Eiznhamer D, Aggarwal SK, Blazar BR, Lee SJ. Jagasia M, et al. J Clin Oncol. 2021 Jun 10;39(17):1888-1898. doi: 10.1200/JCO.20.02754. Epub 2021 Apr 20. J Clin Oncol. 2021. PMID: 33877856 Free PMC article. Clinical Trial.

2

Inhibition of ROCK ameliorates pulmonary fibrosis by suppressing M2 macrophage polarisation through phosphorylation of STAT3.

Li Q, Cheng Y, Zhang Z, Bi Z, Ma X, Wei Y, Wei X. Li Q, et al. Clin Transl Med. 2022 Oct;12(10):e1036. doi: 10.1002/ctm2.1036. Clin Transl Med. 2022. PMID: 36178087 Free PMC article.

3

ROCK2, a critical regulator of immune modulation and fibrosis has emerged as a therapeutic target in chronic graft-versus-host disease.

Zanin-Zhorov A, Blazar BR. Zanin-Zhorov A, et al. Clin Immunol. 2021 Sep;230:108823. doi: 10.1016/j.clim.2021.108823. Epub 2021 Aug 14. Clin Immunol. 2021. PMID: 34400321 Free PMC article. Review.

4

Belumosudil: First Approval.

Blair HA. Blair HA. Drugs. 2021 Sep;81(14):1677-1682. doi: 10.1007/s40265-021-01593-z. Drugs. 2021. PMID: 34463931 Free PMC article. Review.

5

Rho-associated kinases contribute to the regulation of tau phosphorylation and amyloid metabolism during neuronal plasticity.

Saray H, Süer C, Koşar B, Tan B, Dursun N. Saray H, et al. Pharmacol Rep. 2021 Oct;73(5):1303-1314. doi: 10.1007/s43440-021-00279-3. Epub 2021 Jun 1. Pharmacol Rep. 2021. PMID: 34060063

6

TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway.

Wei X, Lou H, Zhou D, Jia Y, Li H, Huang Q, Ma J, Yang Z, Sun C, Meng Y, Xu S, Yang X, Li X, Ji T, Guo Z, Gao Q. Wei X, et al. J Exp Clin Cancer Res. 2021 Sep 19;40(1):292. doi: 10.1186/s13046-021-02091-6. J Exp Clin Cancer Res. 2021. PMID: 34538264 Free PMC article.

7

miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer's disease.

Zheng K, Hu F, Zhou Y, Zhang J, Zheng J, Lai C, Xiong W, Cui K, Hu YZ, Han ZT, Zhang HH, Chen JG, Man HY, Liu D, Lu Y, Zhu LQ. Zheng K, et al. Nat Commun. 2021 Mar 26;12(1):1903. doi: 10.1038/s41467-021-22196-y. Nat Commun. 2021. PMID: 33771994 Free PMC article.

8

Role of Rho in Salt-Sensitive Hypertension.

Kawarazaki W, Fujita T. Kawarazaki W, et al. Int J Mol Sci. 2021 Mar 15;22(6):2958. doi: 10.3390/ijms22062958. Int J Mol Sci. 2021. PMID: 33803946 Free PMC article. Review.

9

S1PR2/RhoA/ROCK1 pathway promotes inflammatory bowel disease by inducing intestinal vascular endothelial barrier damage and M1 macrophage polarization.

Wang X, Chen S, Xiang H, Wang X, Xiao J, Zhao S, Shu Z, Ouyang J, Liang Z, Deng M, Chen X, Zhang J, Liu H, Quan Q, Gao P, Fan J, Chen AF, Lu H. Wang X, et al. Biochem Pharmacol. 2022 Jul;201:115077. doi: 10.1016/j.bcp.2022.115077. Epub 2022 May 10. Biochem Pharmacol. 2022. PMID: 35537530

10

circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2.

Peng L, Sang H, Wei S, Li Y, Jin D, Zhu X, Li X, Dang Y, Zhang G. Peng L, et al. Mol Cancer. 2020 Nov 5;19(1):156. doi: 10.1186/s12943-020-01270-x. Mol Cancer. 2020. PMID: 33153478 Free PMC article.

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