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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1949 1
1951 1
1952 3
1953 5
1954 4
1955 6
1956 4
1957 5
1958 8
1959 4
1960 1
1961 1
1962 1
1964 3
1965 20
1966 47
1967 34
1968 57
1969 55
1970 86
1971 92
1972 123
1973 195
1974 170
1975 281
1976 269
1977 243
1978 256
1979 261
1980 320
1981 384
1982 382
1983 436
1984 494
1985 450
1986 442
1987 401
1988 440
1989 513
1990 520
1991 541
1992 504
1993 625
1994 610
1995 597
1996 677
1997 672
1998 693
1999 780
2000 771
2001 841
2002 840
2003 977
2004 979
2005 1097
2006 1164
2007 1083
2008 1186
2009 1195
2010 1220
2011 1304
2012 1311
2013 1378
2014 1415
2015 1347
2016 1316
2017 1416
2018 1417
2019 1556
2020 1559
2021 1584
2022 1591
2023 1371
2024 532

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39,417 results

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Page 1
Enteral nutritional therapy for induction of remission in Crohn's disease.
Narula N, Dhillon A, Zhang D, Sherlock ME, Tondeur M, Zachos M. Narula N, et al. Cochrane Database Syst Rev. 2018 Apr 1;4(4):CD000542. doi: 10.1002/14651858.CD000542.pub3. Cochrane Database Syst Rev. 2018. PMID: 29607496 Free PMC article. Review.
DATA COLLECTION AND ANALYSIS: Data were extracted independently by at least two authors. The primary outcome was clinical remission. Secondary outcomes included adverse events, serious adverse events and withdrawal due to adverse events. ...Common adverse events rep …
DATA COLLECTION AND ANALYSIS: Data were extracted independently by at least two authors. The primary outcome was clinical remission. …
Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS).
CONSENSUS Trial Study Group. CONSENSUS Trial Study Group. N Engl J Med. 1987 Jun 4;316(23):1429-35. doi: 10.1056/NEJM198706043162301. N Engl J Med. 1987. PMID: 2883575 Clinical Trial.
To evaluate the influence of the angiotensin-converting-enzyme inhibitor enalapril (2.5 to 40 mg per day) on the prognosis of severe congestive heart failure (New York Heart Association [NYHA] functional class IV), we randomly assigned 253 patients in a double-blind study …
To evaluate the influence of the angiotensin-converting-enzyme inhibitor enalapril (2.5 to 40 mg per day) on the prognosis of severe congest …
Beyond benzodiazepines: a meta-analysis and narrative synthesis of the efficacy and safety of alternative options for alcohol withdrawal syndrome management.
Fluyau D, Kailasam VK, Pierre CG. Fluyau D, et al. Eur J Clin Pharmacol. 2023 Sep;79(9):1147-1157. doi: 10.1007/s00228-023-03523-2. Epub 2023 Jun 28. Eur J Clin Pharmacol. 2023. PMID: 37380897 Review.
Randomized control trials (RCTs) were included, omitted were nonblinded trials, blinded trials that were not randomized, and open-label studies. ...Meta-analysis favored gabapentin over chlordiazepoxide and lorazepam (d = 0.563, p < 0.001) and carbamazepine over …
Randomized control trials (RCTs) were included, omitted were nonblinded trials, blinded trials that were not randomized, and o …
Peripheral edema associated with calcium channel blockers: incidence and withdrawal rate--a meta-analysis of randomized trials.
Makani H, Bangalore S, Romero J, Htyte N, Berrios RS, Makwana H, Messerli FH. Makani H, et al. J Hypertens. 2011 Jul;29(7):1270-80. doi: 10.1097/HJH.0b013e3283472643. J Hypertens. 2011. PMID: 21558959
It has been thought to occur secondary to arteriolar dilatation causing intracapillary hypertension and fluid extravasation. We aimed to evaluate the incidence and withdrawal rate of peripheral edema with CCBs. METHODS: A systematic search was made in PubMed, EMBASE and CE …
It has been thought to occur secondary to arteriolar dilatation causing intracapillary hypertension and fluid extravasation. We aimed to eva …
Adverse effects.
Rossini PM. Rossini PM. Clin Ter. 2010;161(1):89-90. Clin Ter. 2010. PMID: 20393687
Studies are used to define the dosage to be used in human testing (Phase 1) as well as to calculate the maximum admissible daily intake. Imperfections in clinical trials sometimes lead to public health disasters and the withdrawal of the drug from commerce. ...Diagn …
Studies are used to define the dosage to be used in human testing (Phase 1) as well as to calculate the maximum admissible daily intake. Imp …
IL-23 blockade with guselkumab potentially modifies psoriasis pathogenesis: rationale and study protocol of a phase 3b, randomised, double-blind, multicentre study in participants with moderate-to-severe plaque-type psoriasis (GUIDE).
Eyerich K, Weisenseel P, Pinter A, Schäkel K, Asadullah K, Wegner S, Muñoz-Elias EJ, Bartz H, Taut FJH, Reich K. Eyerich K, et al. BMJ Open. 2021 Sep 13;11(9):e049822. doi: 10.1136/bmjopen-2021-049822. BMJ Open. 2021. PMID: 34518264 Free PMC article.
Early intervention with guselkumab may result in changes to the clinical disease course versus later intervention. METHODS AND ANALYSIS: Here we present the rationale and design of a phase 3b, randomised, double-blind, multicentre study (GUIDE), comparing treatment …
Early intervention with guselkumab may result in changes to the clinical disease course versus later intervention. METHODS AND ANALYS …
Stiripentol for focal refractory epilepsy.
Brigo F, Storti M. Brigo F, et al. Cochrane Database Syst Rev. 2014 Jan 31;(1):CD009887. doi: 10.1002/14651858.CD009887.pub2. Cochrane Database Syst Rev. 2014. PMID: 24488598 Updated. Review.
The external validity of the study was limited because only responders to stiripentol (that is patients experiencing at least a 50% decrease in seizure frequency compared with baseline) were included in the randomised add on placebo-controlled double-blind phase. Furthermo …
The external validity of the study was limited because only responders to stiripentol (that is patients experiencing at least a 50% decrease …
Electronic Cigarettes for Smoking Cessation: A Systematic Review.
Malas M, van der Tempel J, Schwartz R, Minichiello A, Lightfoot C, Noormohamed A, Andrews J, Zawertailo L, Ferrence R. Malas M, et al. Nicotine Tob Res. 2016 Oct;18(10):1926-1936. doi: 10.1093/ntr/ntw119. Epub 2016 Apr 25. Nicotine Tob Res. 2016. PMID: 27113014 Review.
We included all English-language, empirical quantitative and qualitative papers that investigated primary cessation outcomes (smoking abstinence or reduction) or secondary outcomes (abstinence-related withdrawal symptoms and craving reductions) and were published on or bef …
We included all English-language, empirical quantitative and qualitative papers that investigated primary cessation outcomes (smoking abstin …
Current approach to the treatment of vasovagal syncope in adults.
Hatoum T, Raj S, Sheldon RS. Hatoum T, et al. Intern Emerg Med. 2023 Jan;18(1):23-30. doi: 10.1007/s11739-022-03102-w. Epub 2022 Sep 18. Intern Emerg Med. 2023. PMID: 36117230 Review.
Almost a third of VVS patients continue to faint despite these conservative measures. Metoprolol was not helpful in a pivotal randomized clinical trial. Fludrocortisone and midodrine significantly reduce syncope recurrences with tolerable side effects, when t …
Almost a third of VVS patients continue to faint despite these conservative measures. Metoprolol was not helpful in a pivotal randomized …
Baclofen for alcohol withdrawal.
Liu J, Wang LN. Liu J, et al. Cochrane Database Syst Rev. 2015 Apr 3;(4):CD008502. doi: 10.1002/14651858.CD008502.pub4. Cochrane Database Syst Rev. 2015. PMID: 25836263 Updated. Review.
We placed no restrictions on language. SELECTION CRITERIA: We included all randomised controlled clinical trials (RCTs) evaluating baclofen versus placebo or any other treatment for people with AWS. We excluded uncontrolled, non-randomised, or quasi-random …
We placed no restrictions on language. SELECTION CRITERIA: We included all randomised controlled clinical trials (RCTs) evalua …
39,417 results
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