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lennox-Gastaut syndrome: an updateon treatment.
Carmant L, Whiting S. Carmant L, et al. Can J Neurol Sci. 2012 Nov;39(6):702-11. doi: 10.1017/s0317167100015535. Can J Neurol Sci. 2012. PMID: 23227575 Review.
Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy. Few current treatment options are effective in improving seizure control. This paper reviews the available treatments of LGS and discusses a new option in Canada, rufinamide. ...In a randomized controlled …
Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy. Few current treatment options are effective in improving seizure …
The efficacy and tolerability of pharmacologic treatment options for Lennox-Gastaut syndrome.
Montouris GD, Wheless JW, Glauser TA. Montouris GD, et al. Epilepsia. 2014 Sep;55 Suppl 4:10-20. doi: 10.1111/epi.12732. Epilepsia. 2014. PMID: 25284033 Free article. Review.
LGS is characterized by a slow spike-wave pattern on electroencephalogram (EEG), cognitive impairment, and multiple seizure types. This mixture of seizure types, along with the need to use more than one type of medication, makes LGS one of the most complicated epile …
LGS is characterized by a slow spike-wave pattern on electroencephalogram (EEG), cognitive impairment, and multiple seizure types. Th …
Treatment and rehabilitation outcomes of children affected with nodding syndrome in Northern Uganda: a descriptive case series.
Gazda S, Kitara DL. Gazda S, et al. Pan Afr Med J. 2018 Apr 26;29:228. doi: 10.11604/pamj.2018.29.228.13627. eCollection 2018. Pan Afr Med J. 2018. PMID: 30100981 Free PMC article.
INTRODUCTION: Nodding Syndrome (NS) is a neurological disorder affecting children 5-15 years at onset in East Africa. A major criterion for diagnosis is atonic seizure with dorso-ventral "nodding" of the head. Comorbidities include psychological and behavioral abnor …
INTRODUCTION: Nodding Syndrome (NS) is a neurological disorder affecting children 5-15 years at onset in East Africa. A major criterion for …
Vagus nerve stimulation vs. corpus callosotomy in the treatment of Lennox-Gastaut syndrome: a meta-analysis.
Lancman G, Virk M, Shao H, Mazumdar M, Greenfield JP, Weinstein S, Schwartz TH. Lancman G, et al. Seizure. 2013 Jan;22(1):3-8. doi: 10.1016/j.seizure.2012.09.014. Epub 2012 Oct 12. Seizure. 2013. PMID: 23068970 Free PMC article. Review.
RESULTS: 17 VNS and 9 CC studies met the criteria for inclusion. CC had a significantly better outcome than VNS for >50% atonic seizure reduction (80.0% [67.0-90.0%] vs. 54.1% [32.1-75.4%], p<0.05) and for >75% atonic seizure reduction (70.0% …
RESULTS: 17 VNS and 9 CC studies met the criteria for inclusion. CC had a significantly better outcome than VNS for >50% atonic …