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Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Arlt W, Bancos I, Dralle H, Newell-Price J, Sahdev A, Tabarin A, Terzolo M, Tsagarakis S, Dekkers OM. Fassnacht M, et al. Eur J Endocrinol. 2016 Aug;175(2):G1-G34. doi: 10.1530/EJE-16-0467. Eur J Endocrinol. 2016. PMID: 27390021 Free article.
; (B) How to define and manage low-level autonomous cortisol secretion, formerly called 'subclinical' Cushing's syndrome?; (C) Who should have surgical treatment and how should it be performed?...(iii) For patients without clinical signs of overt Cushing's syndro
; (B) How to define and manage low-level autonomous cortisol secretion, formerly called 'subclinical' Cushing's syndrome?; (C) …
Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease.
Tikkanen E, Havulinna AS, Palotie A, Salomaa V, Ripatti S. Tikkanen E, et al. Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2261-6. doi: 10.1161/ATVBAHA.112.301120. Epub 2013 Apr 18. Arterioscler Thromb Vasc Biol. 2013. PMID: 23599444 Free PMC article.
During the median follow-up time of 12 years (interquartile range 8.75-15.25 years), we observed 1093 CHD, 1552 cardiovascular disease, and 731 acute coronary syndrome events. Adding genetic information to conventional risk factors and family history improved risk discrimi …
During the median follow-up time of 12 years (interquartile range 8.75-15.25 years), we observed 1093 CHD, 1552 cardiovascular disease, and …
Review of tegaserod in the treatment of irritable bowel syndrome.
Patel S, Berrada D, Lembo A. Patel S, et al. Expert Opin Pharmacother. 2004 Nov;5(11):2369-79. doi: 10.1517/14656566.5.11.2369. Expert Opin Pharmacother. 2004. PMID: 15500384 Review.
Tegaserod is currently approved by the FDA for the treatment of women with constipation-predominant irritable bowel syndrome (C-IBS). Eight large Phase III clinical trials involving > 5000 IBS patients support the clinical efficacy of tegaserod in this group of p …
Tegaserod is currently approved by the FDA for the treatment of women with constipation-predominant irritable bowel syndrome (C
Phenotype and genotype in patients with Larsen syndrome: clinical homogeneity and allelic heterogeneity in seven patients.
Girisha KM, Bidchol AM, Graul-Neumann L, Gupta A, Hehr U, Lessel D, Nader S, Shah H, Wickert J, Kutsche K. Girisha KM, et al. BMC Med Genet. 2016 Apr 6;17:27. doi: 10.1186/s12881-016-0290-6. BMC Med Genet. 2016. PMID: 27048506 Free PMC article.
Contrary to the widely described advanced carpal ossification, we noted delay in two patients. We identified the five novel mutations c.4927G A/p.(Gly1643Ser), c.4876G > T / p.(Gly1626Trp), c.4664G > A / p.(Gly1555Asp), c.2055G > C / p. …
Contrary to the widely described advanced carpal ossification, we noted delay in two patients. We identified the five novel mutations c
Management of chronic constipation in general practice.
Bellini M, Gambaccini D, Salvadori S, Tosetti C, Urbano MT, Costa F, Monicelli P, Mumolo MG, Ricchiuti A, De Bortoli N, Marchi S. Bellini M, et al. Tech Coloproctol. 2014 Jun;18(6):543-9. doi: 10.1007/s10151-013-1093-9. Epub 2013 Nov 22. Tech Coloproctol. 2014. PMID: 24272606
METHODS: Over the course of 1 month, 41 GPs recorded tests and therapies suggested to patients complaining of chronic constipation. They were classified according to the Rome III criteria as constipated irritable bowel syndrome (C-IBS), functional constipatio …
METHODS: Over the course of 1 month, 41 GPs recorded tests and therapies suggested to patients complaining of chronic constipation. T …
Congenital nephrotic syndrome: prenatal diagnosis and genetic counselling by estimation of aminotic-fluid and maternal serum alpha-fetoprotein.
Seppälä M, Rapola J, Huttunen NP, Aula P, Karjalainen O, Ruoslahti E. Seppälä M, et al. Lancet. 1976 Jul 17;2(7977):123-5. doi: 10.1016/s0140-6736(76)92847-6. Lancet. 1976. PMID: 59186
Nine families in which a previous child had had congenital nephrotic syndrome (C.N.) sought genetic counselling and possible antenatal diagnosis of fetal disease. ...These pregnancies were terminated, and electron microscopy of the fetal kidneys showed evidence of …
Nine families in which a previous child had had congenital nephrotic syndrome (C.N.) sought genetic counselling and possible a …
C-reactive protein and acute coronary syndrome: comparison of conservative and interventional management.
Munir TA, Afzal MN. Munir TA, et al. J Ayub Med Coll Abbottabad. 2007 Apr-Jun;19(2):26-31. J Ayub Med Coll Abbottabad. 2007. PMID: 18183714
METHODS: High sensitivity C-reactive protein was measured by Immunoturbiditory method in 50 healthy controls and 100 patients of acute coronary syndrome on conservative or interventional management. ...CONCLUSION: Serum C-reactive protein levels were found to …
METHODS: High sensitivity C-reactive protein was measured by Immunoturbiditory method in 50 healthy controls and 100 patients of acut …
Treatment of metabolic syndrome slows progression of diabetic nephropathy.
Duran-Perez EG, Almeda-Valdes P, Cuevas-Ramos D, Campos-Barrera E, Muñoz-Hernandez L, Gomez-Perez FJ. Duran-Perez EG, et al. Metab Syndr Relat Disord. 2011 Dec;9(6):483-9. doi: 10.1089/met.2011.0056. Epub 2011 Aug 29. Metab Syndr Relat Disord. 2011. PMID: 21875335
Subjects were classified in two groups: (1) With correction of metabolic syndrome and (2) without correction of metabolic syndrome at follow-up. Furthermore, they were stratified in four subgroups: (A) Without metabolic syndrome at baseline and at follow-up, …
Subjects were classified in two groups: (1) With correction of metabolic syndrome and (2) without correction of metabolic syndrome
Percutaneous angioplasty and stenting of left subclavian artery lesions for the treatment of patients with concomitant vertebral and coronary subclavian steal syndrome.
Filippo F, Francesco M, Francesco R, Corrado A, Chiara M, Valentina C, Giuseppina N, Salvatore N. Filippo F, et al. Cardiovasc Intervent Radiol. 2006 May-Jun;29(3):348-53. doi: 10.1007/s00270-004-0265-4. Cardiovasc Intervent Radiol. 2006. PMID: 16502184
OBJECTIVE: To evaluate the efficacy of subclavian stenosis percutaneous transfemoral angioplasty (PTA)-treatment in patients with intermittent or complete subclavian steal syndrome (SSS), and coronary-subclavian steal syndrome (C-SSS) after left internal mamm …
OBJECTIVE: To evaluate the efficacy of subclavian stenosis percutaneous transfemoral angioplasty (PTA)-treatment in patients with intermitte …
Differences in the nonreducing ends of heparan sulfates excreted by patients with mucopolysaccharidoses revealed by bacterial heparitinases: a new tool for structural studies and differential diagnosis of Sanfilippo's and Hunter's syndromes.
Toma L, Dietrich CP, Nader HB. Toma L, et al. Lab Invest. 1996 Dec;75(6):771-81. Lab Invest. 1996. PMID: 8973472
The heparan sulfates from patients with Sanfilippo A (deficient in heparan N-sulfatase) and Sanfilippo B (deficient in alpha-N-acetylglucosaminidase) were degraded with heparitinase II producing, besides unsaturated disaccharides, substantial amounts of glucosamine N-sulfate and …
The heparan sulfates from patients with Sanfilippo A (deficient in heparan N-sulfatase) and Sanfilippo B (deficient in alpha-N-acetylglucosa …