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Mitochondrial cardiomyopathy: pathophysiology, diagnosis, and management.
Meyers DE, Basha HI, Koenig MK. Meyers DE, et al. Tex Heart Inst J. 2013;40(4):385-94. Tex Heart Inst J. 2013. PMID: 24082366 Free PMC article. Review.
Mitochondrial disease is a heterogeneous group of multisystemic diseases that develop consequent to mutations in nuclear or mitochondrial DNA. ...In this review, we describe the complex pathophysiology of mitochondrial disease and its clinical features. We fo …
Mitochondrial disease is a heterogeneous group of multisystemic diseases that develop consequent to mutations in nuclear or mitoch …
Advances in Diagnosis and Management of Mitochondrial Cardiomyopathy.
Zhuge R, Zhou R, Ni X. Zhuge R, et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Apr 20;39(2):290-295. doi: 10.3881/j.issn.1000-503X.2017.02.021. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017. PMID: 28483032 Review.
Mitochondrial cardiomyopathy (MCM) is a series of myocardial conditions characterized by abnormal heart-muscle structure,function,or both,secondary to genetic defects involving the mitochondrial respiratory chain,in the absence of concomitant coronary artery …
Mitochondrial cardiomyopathy (MCM) is a series of myocardial conditions characterized by abnormal heart-muscle structure,funct …
Differential Diagnosis of Thick Myocardium according to Histologic Features Revealed by Multiparametric Cardiac Magnetic Resonance Imaging.
Cha MJ, Kim C, Park CH, Hong YJ, Shin JM, Kim TH, Cha YJ, Park CH. Cha MJ, et al. Korean J Radiol. 2022 Jun;23(6):581-597. doi: 10.3348/kjr.2021.0815. Epub 2022 May 9. Korean J Radiol. 2022. PMID: 35555885 Free PMC article. Review.
Left ventricular (LV) wall thickening, or LV hypertrophy (LVH), is common and occurs in diverse conditions including hypertrophic cardiomyopathy (HCM), hypertensive heart disease, aortic valve stenosis, lysosomal storage disorders, cardiac amyloidosis, mitochondrial …
Left ventricular (LV) wall thickening, or LV hypertrophy (LVH), is common and occurs in diverse conditions including hypertrophic cardiom …
The Therapeutic Potential of Targeting Ferroptosis in the Treatment of Mitochondrial Cardiomyopathies and Heart Failure.
Cantrell AC, Zeng H, Chen JX. Cantrell AC, et al. J Cardiovasc Pharmacol. 2024 Jan 1;83(1):23-32. doi: 10.1097/FJC.0000000000001496. J Cardiovasc Pharmacol. 2024. PMID: 37816193
Emerging evidence from our laboratory and others indicates a critical role of mitochondrial Sirtuin 3, a deacetylase linked with longevity and protection against numerous conditions, in the prevention of cardiovascular diseases. Here, we provide a brief overview of the pot …
Emerging evidence from our laboratory and others indicates a critical role of mitochondrial Sirtuin 3, a deacetylase linked with long …
Treatment of two mitochondrial disease patients with a combination of febuxostat and inosine that enhances cellular ATP.
Kamatani N, Kushiyama A, Toyo-Oka L, Toyo-Oka T. Kamatani N, et al. J Hum Genet. 2019 Apr;64(4):351-353. doi: 10.1038/s10038-018-0558-0. Epub 2019 Jan 10. J Hum Genet. 2019. PMID: 30631120
Based on those results, we attempted co-administration of febuxostat and inosine in two patients with mitochondrial disease: one patient with mitochondrial cardiomyopathy and the other patient with mitochondrial diabetes. ...Considering that there is n …
Based on those results, we attempted co-administration of febuxostat and inosine in two patients with mitochondrial disease: one pati …