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Page 1
Treatment of spasticity.
Marsden J, Stevenson V, Jarrett L. Marsden J, et al. Handb Clin Neurol. 2023;196:497-521. doi: 10.1016/B978-0-323-98817-9.00010-7. Handb Clin Neurol. 2023. PMID: 37620087 Review.
Spasticity is characterized by an enhanced size and reduced threshold for activation of stretch reflexes and is associated with "positive signs" such as clonus and spasms, as well as "negative features" such as paresis and a loss of automatic postural responses. ...The cho …
Spasticity is characterized by an enhanced size and reduced threshold for activation of stretch reflexes and is associated with "positive si …
Spasticity: pathophysiology, evaluation and management.
Kheder A, Nair KP. Kheder A, et al. Pract Neurol. 2012 Oct;12(5):289-98. doi: 10.1136/practneurol-2011-000155. Pract Neurol. 2012. PMID: 22976059 Review.
It is part of the upper motor neurone syndrome manifesting as increased tone, clonus, spasms, spastic dystonia and co-contractions. The impact of spasticity varies from it being a subtle neurological sign to severe spasticity causing pain and contractures. ...
It is part of the upper motor neurone syndrome manifesting as increased tone, clonus, spasms, spastic dystonia and co-contractions. T …
The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity.
Dunkley EJ, Isbister GK, Sibbritt D, Dawson AH, Whyte IM. Dunkley EJ, et al. QJM. 2003 Sep;96(9):635-42. doi: 10.1093/qjmed/hcg109. QJM. 2003. PMID: 12925718
RESULTS: Numerous clinical features were associated with serotonin toxicity, but only clonus (inducible, spontaneous or ocular), agitation, diaphoresis, tremor and hyperreflexia were needed for accurate prediction of serotonin toxicity as diagnosed by a clinical toxicologi …
RESULTS: Numerous clinical features were associated with serotonin toxicity, but only clonus (inducible, spontaneous or ocular), agit …
Clonus: definition, mechanism, treatment.
Boyraz I, Uysal H, Koc B, Sarman H. Boyraz I, et al. Med Glas (Zenica). 2015 Feb;12(1):19-26. Med Glas (Zenica). 2015. PMID: 25669332 Review.
Clonus may be found at the ankle, patella, triceps surae, wrist, jaw, biceps brachii. In general, clonus may occur in any muscle with a frequency of 5-8 Hz and the average period of oscillations of the ankle clonus is approximately 160-200 ms. ...
Clonus may be found at the ankle, patella, triceps surae, wrist, jaw, biceps brachii. In general, clonus may occur in any musc
Postanaesthetic shivering: epidemiology, pathophysiology, and approaches to prevention and management.
Alfonsi P. Alfonsi P. Drugs. 2001;61(15):2193-205. doi: 10.2165/00003495-200161150-00004. Drugs. 2001. PMID: 11772130 Review.
The distinguishing factor during electromyogram recordings between patients with postanaesthetic shivering and shivering in fully awake patients is the existence of clonus similar to that recorded in patients with spinal cord transection. Clonus coexists with the cl …
The distinguishing factor during electromyogram recordings between patients with postanaesthetic shivering and shivering in fully awake pati …
Postanaesthetic shivering. Epidemiology, pathophysiology and approaches to prevention and management.
Alfonsi P. Alfonsi P. Minerva Anestesiol. 2003 May;69(5):438-42. Minerva Anestesiol. 2003. PMID: 12768180 Free article. Review.
During EMG records, the distinguishing factor from shivering in fully awake patients is the existence of clonus similar to that recorded in patients with spinal cord transection. ...
During EMG records, the distinguishing factor from shivering in fully awake patients is the existence of clonus similar to that recor …
Neurological complications of psychiatric drugs: clinical features and management.
Haddad PM, Dursun SM. Haddad PM, et al. Hum Psychopharmacol. 2008 Jan;23 Suppl 1:15-26. doi: 10.1002/hup.918. Hum Psychopharmacol. 2008. PMID: 18098217 Review.
Serotonin toxicity comprises altered mental state (agitation, excitement, confusion), neuromuscular hyperactivity (tremor, clonus, myoclonus, hyper-reflexia) and autonomic hyperactivity and occurs on a spectrum. ...
Serotonin toxicity comprises altered mental state (agitation, excitement, confusion), neuromuscular hyperactivity (tremor, clonus, my …
Serotonin toxicity: a practical approach to diagnosis and treatment.
Isbister GK, Buckley NA, Whyte IM. Isbister GK, et al. Med J Aust. 2007 Sep 17;187(6):361-5. doi: 10.5694/j.1326-5377.2007.tb01282.x. Med J Aust. 2007. PMID: 17874986 Review.
The Hunter Serotonin Toxicity Criteria use a smaller, more specific set of clinical features for diagnosis, including clonus, which has been found to be more specific to serotonin toxicity. ...Less severe toxicity occurs with other combinations, overdoses and even single-d …
The Hunter Serotonin Toxicity Criteria use a smaller, more specific set of clinical features for diagnosis, including clonus, which h …
Tizanidine. A review of its pharmacology, clinical efficacy and tolerability in the management of spasticity associated with cerebral and spinal disorders.
Wagstaff AJ, Bryson HM. Wagstaff AJ, et al. Drugs. 1997 Mar;53(3):435-52. doi: 10.2165/00003495-199753030-00007. Drugs. 1997. PMID: 9074844 Review.
Improvement in muscle tone occurred in 60 to 82% of tizanidine recipients, compared with 60 to 65% of baclofen and 60 to 83% of diazepam recipients. Spasm frequency and clonus are also reduced by tizanidine. The most common adverse effects associated with tizanidine are dr …
Improvement in muscle tone occurred in 60 to 82% of tizanidine recipients, compared with 60 to 65% of baclofen and 60 to 83% of diazepam rec …
Recognition, identification, and diagnosis announcement of neonatal arterial ischemic stroke: A combined exploratory quantitative and qualitative study on parents' lived experiences.
Leal Martins C, Chabrier S, Fluss J. Leal Martins C, et al. Arch Pediatr. 2021 May;28(4):285-290. doi: 10.1016/j.arcped.2021.02.002. Epub 2021 Mar 11. Arch Pediatr. 2021. PMID: 33715932 Free article.
OBJECTIVES: To examine the epidemiology of neonatal arterial ischemic stroke (NAIS) and the chronology of care from early reported manifestations to formal diagnosis obtained by imaging. ...The majority of neonates presented within 48 hours with a mean of 27h after birth, …
OBJECTIVES: To examine the epidemiology of neonatal arterial ischemic stroke (NAIS) and the chronology of care from early reported ma …
16 results