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Recent developments in diagnostics and treatment of neonatal cholestasis.
Feldman AG, Sokol RJ. Feldman AG, et al. Semin Pediatr Surg. 2020 Aug;29(4):150945. doi: 10.1016/j.sempedsurg.2020.150945. Epub 2020 Jul 23. Semin Pediatr Surg. 2020. PMID: 32861449 Free PMC article. Review.
Neonatal cholestasis is characterized by conjugated hyperbilirubinemia in the newborn and young infant and is a sign common to over 100 hepatobiliary and/or metabolic disorders. ...Our improved understanding of bile formation and the enterohepatic circulation of bil …
Neonatal cholestasis is characterized by conjugated hyperbilirubinemia in the newborn and young infant and is a sign common to …
Diagnostic criteria and contributors to Gilbert's syndrome.
Wagner KH, Shiels RG, Lang CA, Seyed Khoei N, Bulmer AC. Wagner KH, et al. Crit Rev Clin Lab Sci. 2018 Mar;55(2):129-139. doi: 10.1080/10408363.2018.1428526. Epub 2018 Feb 1. Crit Rev Clin Lab Sci. 2018. PMID: 29390925 Review.
Hyperbilirubinemia is a well-known condition in the clinical setting; however, the causes of elevated serum bilirubin are diverse, as are the clinical ramifications of this condition. For example, diagnoses of individuals vary depending on whether they exhibit an unconjuga …
Hyperbilirubinemia is a well-known condition in the clinical setting; however, the causes of elevated serum bilirubin are diverse, as …
Italian guidelines for the management and treatment of neonatal cholestasis.
Dani C, Pratesi S, Raimondi F, Romagnoli C; Task Force for Hyperbilirubinemia of the Italian Society of Neonatology. Dani C, et al. Ital J Pediatr. 2015 Oct 1;41:69. doi: 10.1186/s13052-015-0178-7. Ital J Pediatr. 2015. PMID: 26428285 Free PMC article. Review.
Hyperbilirubinemia is a frequent condition affecting newborns during the first two weeks of life and when it lasts more than 14 days it is defined as prolonged jaundice. This condition requires differential diagnosis between the usually benign unconjugated hyperbilirubi …
Hyperbilirubinemia is a frequent condition affecting newborns during the first two weeks of life and when it lasts more than 14 days …
Treatment of Cholestasis in Infants and Young Children.
Heinz N, Vittorio J. Heinz N, et al. Curr Gastroenterol Rep. 2023 Nov;25(11):344-354. doi: 10.1007/s11894-023-00891-8. Epub 2023 Aug 31. Curr Gastroenterol Rep. 2023. PMID: 37651067 Review.
PURPOSE OF REVIEW: Cholestasis is characterized by a conjugated hyperbilirubinemia secondary to impaired bile synthesis, transport, or excretion from the liver. ...An enhanced understanding of the underlying pathophysiology may help guide future development of targe …
PURPOSE OF REVIEW: Cholestasis is characterized by a conjugated hyperbilirubinemia secondary to impaired bile synthesis, trans …
Neonatal lupus: clinical features and management.
Lee LA. Lee LA. Paediatr Drugs. 2004;6(2):71-8. doi: 10.2165/00148581-200406020-00001. Paediatr Drugs. 2004. PMID: 15035648 Review.
Three types of hepatobiliary disease have been observed: liver failure occurring at birth or in utero, transient conjugated hyperbilirubinemia occurring in infants, or transient transaminase elevations occurring in infants. ...Optimal therapy has yet to be de …
Three types of hepatobiliary disease have been observed: liver failure occurring at birth or in utero, transient conjugated hyperb …
Predictors of irinotecan toxicity and efficacy in treatment of metastatic colorectal cancer.
Paulík A, Grim J, Filip S. Paulík A, et al. Acta Medica (Hradec Kralove). 2012;55(4):153-9. doi: 10.14712/18059694.2015.39. Acta Medica (Hradec Kralove). 2012. PMID: 23631285 Free article. Review.
The colorectal cancer ranks high among the malignant tumours in incidence and mortality and irinotecan is standardly used in palliative treatment of metastatic disease in every therapeutic line. Unfortunately, the treatment with irinotecan is often associated with severe t …
The colorectal cancer ranks high among the malignant tumours in incidence and mortality and irinotecan is standardly used in palliative trea …
Incidence and predictors of treatment-related conjugated hyperbilirubinemia during early treatment phases for children with acute lymphoblastic leukemia.
Hashmi SK, Navai SA, Chambers TM, Scheurer ME, Hicks MJ, Rau RE, Gramatges MM. Hashmi SK, et al. Pediatr Blood Cancer. 2020 Feb;67(2):e28063. doi: 10.1002/pbc.28063. Epub 2019 Nov 17. Pediatr Blood Cancer. 2020. PMID: 31736183 Free PMC article.
Conjugated hyperbilirubinemia (CHB) and liver transaminase elevation are known complications of acute lymphoblastic leukemia (ALL) therapy, but host risk factors are poorly understood. ...
Conjugated hyperbilirubinemia (CHB) and liver transaminase elevation are known complications of acute lymphoblastic leukemia ( …
Biliary atresia: pathogenesis and treatment.
Bates MD, Bucuvalas JC, Alonso MH, Ryckman FC. Bates MD, et al. Semin Liver Dis. 1998;18(3):281-93. doi: 10.1055/s-2007-1007164. Semin Liver Dis. 1998. PMID: 9773428 Review.
Untreated, the resulting cholestasis leads to progressive conjugated hyperbilirubinemia, cirrhosis, and hepatic failure. Biliary atresia has an incidence of approximately one in 10,000 live births worldwide. ...Consequently, a prompt evaluation is indicated for any …
Untreated, the resulting cholestasis leads to progressive conjugated hyperbilirubinemia, cirrhosis, and hepatic failure. Bilia …
Findings in percutaneous trans-hepatic cholecysto-cholangiography in neonates and infants presenting with conjugated hyperbilirubinemia: emphasis on differential diagnosis and cholangiographic patterns.
Parra DA, Peters SE, Kohli R, Chamlati R, Connolly BL, Wolinska JM, Ng VL, Temple MJ, John PR, Kamath BM, Ling SC, Fecteau A, Amirabadi A, Amaral JG. Parra DA, et al. BMC Pediatr. 2023 Jan 14;23(1):22. doi: 10.1186/s12887-022-03816-y. BMC Pediatr. 2023. PMID: 36639762 Free PMC article.
BACKGROUND: Biliary atresia (BA) is one of the causes of conjugated hyperbilirubinemia in infants which if untreated leads to end-stage liver disease and death. ...CONCLUSION: PTCC is a minimally invasive study in the diagnostic work-up of infants presenting with …
BACKGROUND: Biliary atresia (BA) is one of the causes of conjugated hyperbilirubinemia in infants which if untreated leads to …
12 results