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1976 1
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Peptide-based synthetic pulmonary surfactant for the treatment of respiratory distress disorders.
Braide-Moncoeur O, Tran NT, Long JR. Braide-Moncoeur O, et al. Curr Opin Chem Biol. 2016 Jun;32:22-8. doi: 10.1016/j.cbpa.2016.02.012. Epub 2016 Mar 10. Curr Opin Chem Biol. 2016. PMID: 26970670 Review.
KL4 (sinapultide) represents the first peptide-based replacement for surfactant protein B in pulmonary surfactant (PS) therapies approved for clinical use. Surfaxin, its formulation with PS lipids, shows the promise of synthetic PS for replacing animal-derived PS in the tr …
KL4 (sinapultide) represents the first peptide-based replacement for surfactant protein B in pulmonary surfactant (PS) therapies appr …
State of the art management of transfusion-related acute lung injury (TRALI).
Goldberg AD, Kor DJ. Goldberg AD, et al. Curr Pharm Des. 2012;18(22):3273-84. doi: 10.2174/1381612811209023273. Curr Pharm Des. 2012. PMID: 22621274 Review.
Indeed, current recommendations are primarily based on data extrapolated from trials of the histo-pathologically similar Acute Lung Injury and Acute Respiratory Distress Syndromes. The cornerstone of TRALI management is supportive care with oxygen supp …
Indeed, current recommendations are primarily based on data extrapolated from trials of the histo-pathologically similar Acute Lung Injury a …
The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19.
Xu Y, Baylink DJ, Chen CS, Reeves ME, Xiao J, Lacy C, Lau E, Cao H. Xu Y, et al. J Transl Med. 2020 Aug 26;18(1):322. doi: 10.1186/s12967-020-02488-5. J Transl Med. 2020. PMID: 32847594 Free PMC article. Review.
COVID-19 is caused by a highly infectious novel coronavirus known as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), leading to an acute infectious disease with mild-to-severe clinical symptoms such as flu-like symptoms, fever, headache, dry cough, muscle pai …
COVID-19 is caused by a highly infectious novel coronavirus known as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), le …
The diagnosis and treatment of acute respiratory failure in sepsis.
Wilson RF. Wilson RF. Heart Lung. 1976 Jul-Aug;5(4):614-20. Heart Lung. 1976. PMID: 1047056
Early diagnosis is mandatory in the adult respiratory distress syndromes, particularly in sepsis, and therapy should begin as soon as there is a reasonable suspicion that this problem is developing. Blood-gas changes cannot usually be appreciated clini …
Early diagnosis is mandatory in the adult respiratory distress syndromes, particularly in sepsis, and therapy sh …