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Short-Wavelength Sensitive Cone (S-cone) Testing as an Outcome Measure for NR2E3 Clinical Treatment Trials.
Roman AJ, Powers CA, Semenov EP, Sheplock R, Aksianiuk V, Russell RC, Sumaroka A, Garafalo AV, Cideciyan AV, Jacobson SG. Roman AJ, et al. Int J Mol Sci. 2019 May 21;20(10):2497. doi: 10.3390/ijms20102497. Int J Mol Sci. 2019. PMID: 31117170 Free PMC article.
Recessively-inherited NR2E3 gene mutations cause an unusual retinopathy with abnormally-increased short-wavelength sensitive cone (S-cone) function, in addition to reduced rod and long/middle-wavelength sensitive cone (L/M-cone) function. ... …
Recessively-inherited NR2E3 gene mutations cause an unusual retinopathy with abnormally-increased short-wavelength sensitive cone ( …
Utility in clinical practice of standard vs. high-intensity ERG a-waves.
Marcus M, Cabael L, Marmor MF. Marcus M, et al. Doc Ophthalmol. 2006 Nov;113(3):145-53. doi: 10.1007/s10633-005-5888-5. Doc Ophthalmol. 2006. PMID: 17103246
RESULTS: The standard scotopic a-wave amplitude followed the high-intensity a-wave closely among patients with different diagnoses, and the results did not change significantly when cone a-waves were subtracted to isolate rod signals. The only exception was one patient wit …
RESULTS: The standard scotopic a-wave amplitude followed the high-intensity a-wave closely among patients with different diagnoses, and the …