Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1990 1
1995 1
2001 1
2002 2
2003 2
2004 2
2005 4
2006 6
2007 7
2008 10
2009 12
2010 29
2011 21
2012 37
2013 29
2014 41
2015 44
2016 59
2017 61
2018 67
2019 74
2020 98
2021 115
2022 119
2023 113
2024 44

Text availability

Article attribute

Article type

Publication date

Search Results

900 results

Results by year

Filters applied: . Clear all
Page 1
Endovascular Applications for the Management of High-Grade Gliomas in the Modern Era.
Kappel AD, Jha R, Guggilapu S, Smith WJ, Feroze AH, Dmytriw AA, Vicenty-Padilla J, Alcedo Guardia RE, Gessler FA, Patel NJ, Du R, See AP, Peruzzi PP, Aziz-Sultan MA, Bernstock JD. Kappel AD, et al. Cancers (Basel). 2024 Apr 22;16(8):1594. doi: 10.3390/cancers16081594. Cancers (Basel). 2024. PMID: 38672676 Free PMC article. Review.
This treatment modality may offer the ability to deliver anti-tumoral therapies directly to tumor regions while minimizing systemic toxicity. However, challenges persist, including blood-brain barrier (BBB) penetration, hemodynamic complexities, and drug-tumo …
This treatment modality may offer the ability to deliver anti-tumoral therapies directly to tumor regions while minimizing systemic toxicity …
Focused Ultrasound-Enhanced Liquid Biopsy: A Promising Diagnostic Tool for Brain Tumor Patients.
Bakker A, Ixkes AE, Venugopal H, Ries MG, Lak NSM, de Vos FYFL, van Vuurden DG, Snijders TJ. Bakker A, et al. Cancers (Basel). 2024 Apr 19;16(8):1576. doi: 10.3390/cancers16081576. Cancers (Basel). 2024. PMID: 38672658 Free PMC article. Review.
The performance of minimally invasive molecular diagnostic tools in brain tumors, such as liquid biopsy, has so far been limited by the blood-brain barrier (BBB). The BBB hinders the release of brain tumor biomarkers into the bloodstream. The use of focuse …
The performance of minimally invasive molecular diagnostic tools in brain tumors, such as liquid biopsy, has so far been limited by the b …
Recent advances of focused ultrasound induced blood-brain barrier opening for clinical applications of neurodegenerative diseases.
Zhao P, Wu T, Tian Y, You J, Cui X. Zhao P, et al. Adv Drug Deliv Rev. 2024 Apr 21:115323. doi: 10.1016/j.addr.2024.115323. Online ahead of print. Adv Drug Deliv Rev. 2024. PMID: 38653402 Review.
With the aging population on the rise, neurodegenerative disorders have taken center stage as a significant health concern. The blood-brain barrier (BBB) plays an important role to maintain the stability of central nervous system, yet it poses a formidable ob …
With the aging population on the rise, neurodegenerative disorders have taken center stage as a significant health concern. The blood …
Ultrasmall iron oxide nanoparticles with MRgFUS for enhanced magnetic resonance imaging of orthotopic glioblastoma.
Chen J, Yang R, Yu H, Wu H, Wu N, Wang S, Yin X, Shi X, Wang H. Chen J, et al. J Mater Chem B. 2024 Apr 22. doi: 10.1039/d3tb02966b. Online ahead of print. J Mater Chem B. 2024. PMID: 38647018
At present, the main challenge is the effective hindering of biological barriers, including the blood-brain barrier (BBB) and the blood-brain tumor barrier (BBTB). Herein, we aimed to investigate whether the USIO NPs, in combination with MR-guided focused …
At present, the main challenge is the effective hindering of biological barriers, including the blood-brain barrier (BB …
Optimal timing for drug delivery into the hippocampus by focused ultrasound: A comparison of hydrophilic and lipophilic compounds.
Seo Y, Chang KW, Lee J, Kong C, Shin J, Chang JW, Na YC, Chang WS. Seo Y, et al. Heliyon. 2024 Apr 9;10(8):e29480. doi: 10.1016/j.heliyon.2024.e29480. eCollection 2024 Apr 30. Heliyon. 2024. PMID: 38644896 Free PMC article.
AIMS: Previous studies have reported that focused ultrasound (FUS) helps modulate the blood-brain barrier (BBB). ...
AIMS: Previous studies have reported that focused ultrasound (FUS) helps modulate the blood-brain barrier …
Current clinical investigations of focused ultrasound blood-brain barrier disruption: A review.
Durham PG, Butnariu A, Alghorazi R, Pinton G, Krishna V, Dayton PA. Durham PG, et al. Neurotherapeutics. 2024 Apr 17;21(3):e00352. doi: 10.1016/j.neurot.2024.e00352. Online ahead of print. Neurotherapeutics. 2024. PMID: 38636309 Free PMC article. Review.
The blood-brain barrier (BBB) presents a formidable challenge in delivering therapeutic agents to the central nervous system. Ultrasound-mediated BBB disruption has emerged as a promising non-invasive technique to enhance drug delivery to the brain. .. …
The blood-brain barrier (BBB) presents a formidable challenge in delivering therapeutic agents to the central nervous s …
Feasibility of measuring blood-brain barrier permeability using ultra-short echo time radial magnetic resonance imaging.
Bae J, Qayyum S, Zhang J, Das A, Reyes I, Aronowitz E, Stavarache MA, Kaplitt MG, Masurkar A, Kim SG. Bae J, et al. J Neuroimaging. 2024 Apr 14. doi: 10.1111/jon.13199. Online ahead of print. J Neuroimaging. 2024. PMID: 38616297
BACKGROUND AND PURPOSE: The purpose of this study is to evaluate the feasibility of using 3-dimensional (3D) ultra-short echo time (UTE) radial imaging method for measurement of the permeability of the blood-brain barrier (BBB) to gadolinium-based contrast ag …
BACKGROUND AND PURPOSE: The purpose of this study is to evaluate the feasibility of using 3-dimensional (3D) ultra-short echo time (UTE) rad …
Remotely controlled drug release in deep brain regions of non-human primates.
Wilson MG, Webb TD, Odéen H, Kubanek J. Wilson MG, et al. J Control Release. 2024 Apr 16;369:775-785. doi: 10.1016/j.jconrel.2024.04.013. Online ahead of print. J Control Release. 2024. PMID: 38604386
Many areas of science and medicine would benefit from selective release of drugs in specific regions. Nanoparticle drug carriers activated by focused ultrasound-remotely applied, depth-penetrating energy-may provide such selective interventions. ...The release rever …
Many areas of science and medicine would benefit from selective release of drugs in specific regions. Nanoparticle drug carriers activated b …
Strategies to Improve Drug Delivery Across the Blood-Brain Barrier for Glioblastoma.
Narsinh KH, Perez E, Haddad AF, Young JS, Savastano L, Villanueva-Meyer JE, Winkler E, de Groot J. Narsinh KH, et al. Curr Neurol Neurosci Rep. 2024 May;24(5):123-139. doi: 10.1007/s11910-024-01338-x. Epub 2024 Apr 5. Curr Neurol Neurosci Rep. 2024. PMID: 38578405 Free PMC article. Review.
New approaches to drug delivery and clinical trial design are needed. RECENT FINDINGS: We discuss how the blood-brain barrier and tumor microenvironment pose challenges for development of effective therapies for glioblastoma. Next, we discuss treatments in de …
New approaches to drug delivery and clinical trial design are needed. RECENT FINDINGS: We discuss how the blood-brain barri …
Enhanced capillary delivery with nanobubble-mediated blood-brain barrier opening and advanced high resolution vascular segmentation.
Gattegno R, Arbel L, Riess N, Shinar H, Katz S, Ilovitsh T. Gattegno R, et al. J Control Release. 2024 Apr 8;369:506-516. doi: 10.1016/j.jconrel.2024.04.001. Online ahead of print. J Control Release. 2024. PMID: 38575074
Overcoming the blood-brain barrier (BBB) is essential to enhance brain therapy. Here, we utilized nanobubbles with focused ultrasound for targeted and improved BBB opening in mice. ...
Overcoming the blood-brain barrier (BBB) is essential to enhance brain therapy. Here, we utilized nanobubbles with f …
900 results