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1992 1
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2010 1
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2016 5
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45 results

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Page 1
Advances in the clinical management of uveal melanoma.
Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S. Carvajal RD, et al. Nat Rev Clin Oncol. 2023 Feb;20(2):99-115. doi: 10.1038/s41571-022-00714-1. Epub 2023 Jan 4. Nat Rev Clin Oncol. 2023. PMID: 36600005 Review.
Until January 2022, no systemic therapy had received regulatory approval for patients with metastatic uveal melanoma, and these patients have historically had a dismal prognosis owing to the limited efficacy of the available treatments. ...In this Revi …
Until January 2022, no systemic therapy had received regulatory approval for patients with metastatic uveal melanoma …
Metastatic disease from uveal melanoma: treatment options and future prospects.
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD. Carvajal RD, et al. Br J Ophthalmol. 2017 Jan;101(1):38-44. doi: 10.1136/bjophthalmol-2016-309034. Epub 2016 Aug 29. Br J Ophthalmol. 2017. PMID: 27574175 Free PMC article. Review.
Uveal melanoma represents 85% of all ocular melanomas and up to 50% of patients develop metastatic disease. ...This review explores the biology of uveal melanoma and how this relates to ongoing trials of targeted therapies in the metas …
Uveal melanoma represents 85% of all ocular melanomas and up to 50% of patients develop metastatic disease. ...This rev …
Tebentafusp for the treatment of HLA-A*02:01-positive adult patients with unresectable or metastatic uveal melanoma.
Chen LN, Carvajal RD. Chen LN, et al. Expert Rev Anticancer Ther. 2022 Oct;22(10):1017-1027. doi: 10.1080/14737140.2022.2124971. Epub 2022 Sep 19. Expert Rev Anticancer Ther. 2022. PMID: 36102132 Free PMC article. Review.
INTRODUCTION: Metastatic uveal melanoma is associated with poor prognosis and few treatment options. Tebentafusp recently became the first FDA-approved agent for metastatic uveal melanoma. AREAS COVERED: In this review, we describe the me …
INTRODUCTION: Metastatic uveal melanoma is associated with poor prognosis and few treatment options. Tebentafusp recent …
Novel treatment paradigms for metastatic uveal melanoma.
Patel SP, Katz SC. Patel SP, et al. Cancer Gene Ther. 2022 Dec;29(12):1807-1808. doi: 10.1038/s41417-022-00558-y. Epub 2022 Dec 1. Cancer Gene Ther. 2022. PMID: 36456705 Free PMC article. No abstract available.
Recent advances in uveal melanoma treatment.
Álvarez-Rodríguez B, Latorre A, Posch C, Somoza Á. Álvarez-Rodríguez B, et al. Med Res Rev. 2017 Nov;37(6):1350-1372. doi: 10.1002/med.21460. Epub 2017 Jul 31. Med Res Rev. 2017. PMID: 28759124 Review.
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. ...Currently, there is no effective treatment for metastatic uveal melanoma, and we hope this review will encourage researchers and clinicians to work to find a bet …
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. ...Currently, there is no effective treatment …
Tebentafusp for the treatment of metastatic uveal melanoma.
Schank TE, Hassel JC. Schank TE, et al. Future Oncol. 2022 Apr;18(11):1303-1311. doi: 10.2217/fon-2021-1260. Epub 2022 Feb 17. Future Oncol. 2022. PMID: 35172589 Review.
Uveal melanoma is a rare disease; nevertheless, it is the most common primary intraocular malignancy among adults. ...In approximately half patients who have uveal melanoma, it will spread to other parts of the body, mostly to the liver. ...
Uveal melanoma is a rare disease; nevertheless, it is the most common primary intraocular malignancy among adults. ...In appro …
Management of Uveal Melanoma: Updated Cancer Care Alberta Clinical Practice Guideline.
Weis E, Surgeoner B, Salopek TG, Cheng T, Hyrcza M, Kostaras X, Larocque M, McKinnon G, McWhae J, Menon G, Monzon J, Murtha AD, Walker J, Temple-Oberle C. Weis E, et al. Curr Oncol. 2023 Dec 20;31(1):24-41. doi: 10.3390/curroncol31010002. Curr Oncol. 2023. PMID: 38275828 Free PMC article. Review.
OBJECTIVE: The purpose of this guideline update is to reassess and update recommendations in the prior guideline from 2016 on the appropriate management of patients with uveal melanoma. METHODS: In 2021, a multidisciplinary working group from the Provincial Cutaneou …
OBJECTIVE: The purpose of this guideline update is to reassess and update recommendations in the prior guideline from 2016 on the appropriat …
Epidemiology and management of uveal melanoma.
Yonekawa Y, Kim IK. Yonekawa Y, et al. Hematol Oncol Clin North Am. 2012 Dec;26(6):1169-84. doi: 10.1016/j.hoc.2012.08.004. Hematol Oncol Clin North Am. 2012. PMID: 23116575 Review.
Uveal melanoma is the most common primary intraocular malignancy in adults. ...However, there are still no effective therapies against metastatic uveal melanoma, which is almost always fatal. ...
Uveal melanoma is the most common primary intraocular malignancy in adults. ...However, there are still no effective therap …
Selumetinib for the treatment of metastatic uveal melanoma: past and future perspectives.
Komatsubara KM, Manson DK, Carvajal RD. Komatsubara KM, et al. Future Oncol. 2016 Jun;12(11):1331-44. doi: 10.2217/fon-2015-0075. Epub 2016 Apr 5. Future Oncol. 2016. PMID: 27044592 Review.
Uveal melanoma is a rare but aggressive subtype of melanoma. Nearly 50% of patients will develop metastatic disease despite primary enucleation or radiation therapy. There is currently no standard of care therapy for metastatic …
Uveal melanoma is a rare but aggressive subtype of melanoma. Nearly 50% of patients will develop metastatic dise …
Treatment of metastatic uveal melanoma in 2022: improved treatment regimens and improved prognosis.
Reichstein D, Brock A, Lietman C, McKean M. Reichstein D, et al. Curr Opin Ophthalmol. 2022 Nov 1;33(6):585-590. doi: 10.1097/ICU.0000000000000905. Epub 2022 Sep 8. Curr Opin Ophthalmol. 2022. PMID: 36094043 Review.
PURPOSE OF REVIEW: Until recently, metastatic uveal melanoma was associated with essentially uniform fatality within months. ...The first systemic immunotherapy specifically for metastatic uveal melanoma was approved this year. This medic …
PURPOSE OF REVIEW: Until recently, metastatic uveal melanoma was associated with essentially uniform fatality within mo …
45 results