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238 results

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Page 1
The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy.
Wenning GK, Stankovic I, Vignatelli L, Fanciulli A, Calandra-Buonaura G, Seppi K, Palma JA, Meissner WG, Krismer F, Berg D, Cortelli P, Freeman R, Halliday G, Höglinger G, Lang A, Ling H, Litvan I, Low P, Miki Y, Panicker J, Pellecchia MT, Quinn N, Sakakibara R, Stamelou M, Tolosa E, Tsuji S, Warner T, Poewe W, Kaufmann H. Wenning GK, et al. Mov Disord. 2022 Jun;37(6):1131-1148. doi: 10.1002/mds.29005. Epub 2022 Apr 21. Mov Disord. 2022. PMID: 35445419 Free PMC article. Review.
BACKGROUND: The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as the reference standard for clinical research, but lack sensitivity to diagnose the disease at early stages. ...
BACKGROUND: The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as t …
The Differential Diagnosis and Treatment of Atypical Parkinsonism.
Levin J, Kurz A, Arzberger T, Giese A, Höglinger GU. Levin J, et al. Dtsch Arztebl Int. 2016 Feb 5;113(5):61-9. doi: 10.3238/arztebl.2016.0061. Dtsch Arztebl Int. 2016. PMID: 26900156 Free PMC article. Review.
BACKGROUND: Aside from idiopathic Parkinson syndrome (Parkinson's disease), there are a number of other, so-called atypical parkinsonian syndromes: dementia with Lewy bodies (DLB), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corti …
BACKGROUND: Aside from idiopathic Parkinson syndrome (Parkinson's disease), there are a number of other, so-called atypical parkinsonian syn …
Autonomic dysfunction: Diagnosis and management.
Rafanelli M, Walsh K, Hamdan MH, Buyan-Dent L. Rafanelli M, et al. Handb Clin Neurol. 2019;167:123-137. doi: 10.1016/B978-0-12-804766-8.00008-X. Handb Clin Neurol. 2019. PMID: 31753129 Review.
The autonomic nervous system is designed to maintain physiologic homeostasis. Its widespread connections make it vulnerable to disruption by many disease processes including primary etiologies such as Parkinson's disease, multiple system atrophy, demen …
The autonomic nervous system is designed to maintain physiologic homeostasis. Its widespread connections make it vulnerable to disrup …
Pharmacologic treatment of orthostatic hypotension.
Park JW, Okamoto LE, Shibao CA, Biaggioni I. Park JW, et al. Auton Neurosci. 2020 Dec;229:102721. doi: 10.1016/j.autneu.2020.102721. Epub 2020 Aug 28. Auton Neurosci. 2020. PMID: 32979782 Free PMC article. Review.
Nonpharmacologic treatment is always the first step in the management of this condition, but a considerable number of patients will require pharmacologic therapies. Denervation hypersensitivity and impairment of baroreflex buffering makes these patients sensitive to small …
Nonpharmacologic treatment is always the first step in the management of this condition, but a considerable number of patients will require …
Dysphagia in multiple system atrophy consensus statement on diagnosis, prognosis and treatment.
Calandra-Buonaura G, Alfonsi E, Vignatelli L, Benarroch EE, Giannini G, Iranzo A, Low PA, Martinelli P, Provini F, Quinn N, Tolosa E, Wenning GK, Abbruzzese G, Bower P, Antonini A, Bhatia KP, Bonavita J, Pellecchia MT, Pizzorni N, Tison F, Ghorayeb I, Meissner WG, Ozawa T, Pacchetti C, Pozzi NG, Vicini C, Schindler A, Cortelli P, Kaufmann H. Calandra-Buonaura G, et al. Parkinsonism Relat Disord. 2021 May;86:124-132. doi: 10.1016/j.parkreldis.2021.03.027. Epub 2021 Mar 30. Parkinsonism Relat Disord. 2021. PMID: 33839029 Free article. Review.
Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by a combination of autonomic failure plus cerebellar syndrome and/or parkinsonism. ...
Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by a combination of autonomic failure plus …
Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies.
Palma JA, Kaufmann H. Palma JA, et al. Mov Disord. 2018 Mar;33(3):372-390. doi: 10.1002/mds.27344. Mov Disord. 2018. PMID: 29508455 Free PMC article. Review.
Dysfunction of the autonomic nervous system afflicts most patients with Parkinson disease and other synucleinopathies such as dementia with Lewy bodies, multiple system atrophy, and pure autonomic failure, reducing quality of life and increasing mortal …
Dysfunction of the autonomic nervous system afflicts most patients with Parkinson disease and other synucleinopathies such as dementi …
(18)F-FDG PET in Parkinsonism: Differential Diagnosis and Evaluation of Cognitive Impairment.
Meyer PT, Frings L, Rücker G, Hellwig S. Meyer PT, et al. J Nucl Med. 2017 Dec;58(12):1888-1898. doi: 10.2967/jnumed.116.186403. Epub 2017 Sep 14. J Nucl Med. 2017. PMID: 28912150 Free article. Review.
Imaging disease-specific patterns of regional glucose metabolism with PET and (18)F-FDG allows for a highly accurate distinction between Parkinson disease (PD) and atypical parkinsonian syndromes, including multiple-system atrophy, progressive supranuclear pa …
Imaging disease-specific patterns of regional glucose metabolism with PET and (18)F-FDG allows for a highly accurate distinction between Par …
Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases.
Holm A, Hansen SN, Klitgaard H, Kauppinen S. Holm A, et al. RNA Biol. 2022;19(1):594-608. doi: 10.1080/15476286.2022.2066334. Epub 2021 Dec 31. RNA Biol. 2022. PMID: 35482908 Free PMC article.
Furthermore, RNA-based therapeutics have the potential to modulate entire disease pathways, and thereby represent a new modality with unprecedented potential for generating disease-modifying drugs for a wide variety of human diseases, including central nervous system …
Furthermore, RNA-based therapeutics have the potential to modulate entire disease pathways, and thereby represent a new modality with …
The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension.
Gibbons CH, Schmidt P, Biaggioni I, Frazier-Mills C, Freeman R, Isaacson S, Karabin B, Kuritzky L, Lew M, Low P, Mehdirad A, Raj SR, Vernino S, Kaufmann H. Gibbons CH, et al. J Neurol. 2017 Aug;264(8):1567-1582. doi: 10.1007/s00415-016-8375-x. Epub 2017 Jan 3. J Neurol. 2017. PMID: 28050656 Free PMC article. Review.
Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson's disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including amyloid or diabetic …
Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson's disease, multiple …
The REM sleep behavior disorder screening questionnaire--a new diagnostic instrument.
Stiasny-Kolster K, Mayer G, Schäfer S, Möller JC, Heinzel-Gutenbrunner M, Oertel WH. Stiasny-Kolster K, et al. Mov Disord. 2007 Dec;22(16):2386-93. doi: 10.1002/mds.21740. Mov Disord. 2007. PMID: 17894337
Many patients with assumed idiopathic REM sleep behavior disorder (RBD) may actually represent an early clinical manifestation of an evolving neurodegenerative disorder, such as the alpha-synucleinopathies, Parkinson's disease or multiple system atrophy. Earl …
Many patients with assumed idiopathic REM sleep behavior disorder (RBD) may actually represent an early clinical manifestation of an evolvin …
238 results