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Neonatal neutropenia: what diagnostic evaluation is needed and when is treatment recommended?
Del Vecchio A, Christensen RD. Del Vecchio A, et al. Early Hum Dev. 2012 May;88 Suppl 2:S19-24. doi: 10.1016/S0378-3782(12)70007-5. Early Hum Dev. 2012. PMID: 22633505 Review.
Neutropenia is a relatively frequent finding in the neonatal intensive care unit, particularly in very low birth weight neonates during the first week of life. ...Intravenous immunoglobulin, corticosteroids, granulocyte transfusions, and gamma interferon did …
Neutropenia is a relatively frequent finding in the neonatal intensive care unit, particularly in very low birth weight …
Current treatment options to prevent perinatal transmission of herpes simplex virus.
Leung DT, Sacks SL. Leung DT, et al. Expert Opin Pharmacother. 2003 Oct;4(10):1809-19. doi: 10.1517/14656566.4.10.1809. Expert Opin Pharmacother. 2003. PMID: 14521490 Review.
Neonatal herpes is a potentially devastating consequence of perinatal transmission of the herpes simplex virus (HSV), with significant morbidity and mortality. ...Significant experience has been gained with the use of acyclovir in pregnancy and it is recommended for both e …
Neonatal herpes is a potentially devastating consequence of perinatal transmission of the herpes simplex virus (HSV), with significan …
Alloimmune neonatal neutropenia: can we afford the consequences of a missed diagnosis?
Williams BA, Fung YL. Williams BA, et al. J Paediatr Child Health. 2006 Jan-Feb;42(1-2):59-61. doi: 10.1111/j.1440-1754.2006.00774.x. J Paediatr Child Health. 2006. PMID: 16487391
The incidence of alloimmune neonatal neutropenia (ANN) is poorly defined. The reported incidence is less than or equal to 0.1%. This prospective study of unselected pregnancies found an incidence of 0.81% based on results of screening 247 'full term' cord blood samp …
The incidence of alloimmune neonatal neutropenia (ANN) is poorly defined. The reported incidence is less than or equal to 0.1% …
Recent advances in the pathogenesis and treatment of nonimmune neutropenias in the neonate.
Calhoun DA, Christensen RD. Calhoun DA, et al. Curr Opin Hematol. 1998 Jan;5(1):37-41. doi: 10.1097/00062752-199801000-00007. Curr Opin Hematol. 1998. PMID: 9515201 Review.
Neutropenia in the neonate is defined as a significantly lower than normal concentration of neutrophils in the peripheral blood and can be broadly classified as immune or nonimmune. ...Recent advances have been made in the pathogenesis and treatment of several types of …
Neutropenia in the neonate is defined as a significantly lower than normal concentration of neutrophils in the peripheral blood and c …
Human neutrophil alloantigen genotype frequencies in Thai blood donors.
Changsri K, Tobunluepop P, Songthammawat D, Apornsuwan T, Kaset C, Nathalang O. Changsri K, et al. Blood Transfus. 2014 Jan;12 Suppl 1(Suppl 1):s286-91. doi: 10.2450/2013.0161-12. Epub 2013 Jan 23. Blood Transfus. 2014. PMID: 23399362 Free PMC article.
BACKGROUND: Antibodies to human neutrophil antigens (HNA) can cause transfusion reactions, as well as autoimmune and neonatal neutropenia. This study is the first to report the frequencies of human neutrophil antigen genotypes in the Thai population. ...
BACKGROUND: Antibodies to human neutrophil antigens (HNA) can cause transfusion reactions, as well as autoimmune and neonatal neut …
Human neutrophil alloantigen genotype frequencies among blood donors with Turkish and German descent.
Hauck B, Philipp A, Eckstein R, Ott S, Zimmermann R, Dengler T, Zingsem J. Hauck B, et al. Tissue Antigens. 2011 Dec;78(6):416-20. doi: 10.1111/j.1399-0039.2011.01779.x. Tissue Antigens. 2011. PMID: 22077622
Antibodies against the human neutrophil antigens (HNA) are able to stimulate transfusion reactions, autoimmune and neonatal neutropenia. The aim of this study was to determine the HNA allele frequencies in the largest ethnic minority group in Germany in comparison w …
Antibodies against the human neutrophil antigens (HNA) are able to stimulate transfusion reactions, autoimmune and neonatal neutro …
Alloimmune neonatal neutropenia--a neglected diagnosis?
Minchinton RM, McGrath KM. Minchinton RM, et al. Med J Aust. 1987 Aug 3;147(3):139-41. Med J Aust. 1987. PMID: 3600474
Alloimmune neonatal neutropenia is due to maternal IgG neutrophil-specific antibodies that cross the placenta to sensitize fetal neutrophils and cause neutropenia in the neonate. ...The treatment of severe infections in infants with alloimmune neonatal …
Alloimmune neonatal neutropenia is due to maternal IgG neutrophil-specific antibodies that cross the placenta to sensitize fet …
Human Neutrophil Alloantigen Genotype Frequencies Among Syrian Population.
Hauck-Dlimi B, Damrah M, Achenbach S, Ott S, Zimmermann R, Zingsem J, Strobel J. Hauck-Dlimi B, et al. Clin Lab. 2018 Apr 1;64(4):597-601. doi: 10.7754/Clin.Lab.2017.171133. Clin Lab. 2018. PMID: 29739087
BACKGROUND: Human neutrophil antigens (HNA) are able to provoke allo- and autoimmune antibodies which lead to reactions like autoimmune and neonatal neutropenia. However, until now no data about HNA genotype distribution in Syrian population exists. ...Therefore, we …
BACKGROUND: Human neutrophil antigens (HNA) are able to provoke allo- and autoimmune antibodies which lead to reactions like autoimmune and …
Granulocyte colony stimulating factor treatment for neonatal neutropenia.
Russell AR, Davies EG, Ball SE, Gordon-Smith E. Russell AR, et al. Arch Dis Child Fetal Neonatal Ed. 1995 Jan;72(1):F53-4. doi: 10.1136/fn.72.1.f53. Arch Dis Child Fetal Neonatal Ed. 1995. PMID: 7538031 Free PMC article.
In a pilot study recombinant human granulocyte colony-stimulating factor (rhG-CSF) was administered to 12 neutropenic preterm infants to determine if neonatal neutropenia is secondary to decreased endogenous G-CSF production. ...
In a pilot study recombinant human granulocyte colony-stimulating factor (rhG-CSF) was administered to 12 neutropenic preterm infants to det …