Application of a novel score test for genetic association incorporating gene-gene interaction suggests functionality for prostate cancer susceptibility regions.
Ciampa J, Yeager M, Jacobs K, Thun MJ, Gapstur S, Albanes D, Virtamo J, Weinstein SJ, Giovannucci E, Willett WC, Cancel-Tassin G, Cussenot O, Valeri A, Hunter D, Hoover R, Thomas G, Chanock S, Holmes C, Chatterjee N.
Ciampa J, et al.
Hum Hered. 2011;72(3):182-93. doi: 10.1159/000331222. Epub 2011 Nov 11.
Hum Hered. 2011.
PMID: 22086326
Free PMC article.
We use our method in applications designed to detect interactions that generate hypotheses about the functionality of prostate cancer (PRCA) susceptibility regions. METHODS: Our proposed score test is designed to gain additional power through the use of a ret …
We use our method in applications designed to detect interactions that generate hypotheses about the functionality of prostate can …