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Diabetic Retinopathy in the Aging Population: A Perspective of Pathogenesis and Treatment.
Leley SP, Ciulla TA, Bhatwadekar AD. Leley SP, et al. Clin Interv Aging. 2021 Jul 15;16:1367-1378. doi: 10.2147/CIA.S297494. eCollection 2021. Clin Interv Aging. 2021. PMID: 34290499 Free PMC article. Review.
To effectively treat DR within the elderly population, it is essential first to consider the retinal changes that occur due to aging, such as decreased blood flow, retinal thinning, and microglial changes, and understand that these changes can render the reti …
To effectively treat DR within the elderly population, it is essential first to consider the retinal changes that occur due to aging, …
A safety evaluation of ranibizumab in the treatment of age-related macular degeneration.
Gibson JM, Gibson SJ. Gibson JM, et al. Expert Opin Drug Saf. 2014 Sep;13(9):1259-70. doi: 10.1517/14740338.2014.939951. Epub 2014 Aug 5. Expert Opin Drug Saf. 2014. PMID: 25091039 Review.
EXPERT OPINION: Overall, intravitreal ranibizumab can be considered a safe and highly effective drug for patients with wet AMD. However recent concerns about retinal thinning following ranibizumab therapy, possible systemic AE associated with all anti-VEGF dr …
EXPERT OPINION: Overall, intravitreal ranibizumab can be considered a safe and highly effective drug for patients with wet AMD. However rece …
Radiation effects on retinal layers revealed by OCT, OCT-A, and perimetry as a function of dose and time from treatment.
Tamplin MR, Wang JK, Binkley EM, Garvin MK, Hyer DE, Buatti JM, Boldt HC, Grumbach IM, Kardon RH. Tamplin MR, et al. Sci Rep. 2024 Feb 9;14(1):3380. doi: 10.1038/s41598-024-53830-6. Sci Rep. 2024. PMID: 38336828 Free PMC article.
Two eyes showed the opposite: significant inner retinal layer thinning and normal capillary density, indicating early neuronal damage preceding a decrease in capillary density. At later time points, inner retinal thinning becomes the dominant pathology …
Two eyes showed the opposite: significant inner retinal layer thinning and normal capillary density, indicating early neuronal …
Traumatic Maculopathy with Massive Subretinal Hemorrhage after Closed-Globe Injuries: Associated Findings, Management, and Visual Outcomes.
Chen KJ, Sun MH, Sun CC, Wang NK, Hou CH, Wu AL, Wu WC, Lai CC. Chen KJ, et al. Ophthalmol Retina. 2019 Jan;3(1):53-60. doi: 10.1016/j.oret.2018.08.007. Epub 2018 Aug 25. Ophthalmol Retina. 2019. PMID: 30935658
Pars plana vitrectomy usually was performed in patients with persistent vitreous hemorrhage, retinal detachment, lens dislocation, and cyclodialysis cleft with hypotony. ...Thirteen eyes showed VA of 2/200 or less with dense macular scars or foveal atrophy. Foveal atrophy …
Pars plana vitrectomy usually was performed in patients with persistent vitreous hemorrhage, retinal detachment, lens dislocation, an …
Surgical repair of rhegmatogenous retinal detachment after treatment for retinoblastoma.
Baumal CR, Shields CL, Shields JA, Tasman WS. Baumal CR, et al. Ophthalmology. 1998 Nov;105(11):2134-9. doi: 10.1016/S0161-6420(98)91139-3. Ophthalmology. 1998. PMID: 9818618
OBJECTIVE: This study aimed to evaluate the causes of rhegmatogenous retinal detachment in children with retinoblastoma and to assess the surgical approach and results of retinal reattachment surgery. ...Extreme retinal thinning with a possible reti …
OBJECTIVE: This study aimed to evaluate the causes of rhegmatogenous retinal detachment in children with retinoblastoma and to assess …
Genotype-phenotype correlations in Bothnia dystrophy caused by RLBP1 gene sequence variations.
Burstedt M, Jonsson F, Köhn L, Burstedt M, Kivitalo M, Golovleva I. Burstedt M, et al. Acta Ophthalmol. 2013 Aug;91(5):437-44. doi: 10.1111/j.1755-3768.2012.02431.x. Epub 2012 May 2. Acta Ophthalmol. 2013. PMID: 22551409 Free article.
RESULTS: Progressive decline of VA and VF areas was age-dependent. Retinal degenerative maculopathy, peripheral degenerative changes and retinitis punctata albescens (RPA) were present. Early retinal thinning in the central foveal, foveal (O 1 mm), and inner …
RESULTS: Progressive decline of VA and VF areas was age-dependent. Retinal degenerative maculopathy, peripheral degenerative changes …
Genotype phenotype analysis of Bietti's crystalline dystrophy in patients with CYP4V2 mutations.
Lai TY, Ng TK, Tam PO, Yam GH, Ngai JW, Chan WM, Liu DT, Lam DS, Pang CP. Lai TY, et al. Invest Ophthalmol Vis Sci. 2007 Nov;48(11):5212-20. doi: 10.1167/iovs.07-0660. Invest Ophthalmol Vis Sci. 2007. PMID: 17962476
OCT showed the presence of intraretinal crystals in all patients. Patients with more severe thinning of the retina had worse visual acuity, and there was moderate correlation between the OCT central foveal thickness and visual acuity (Spearman rho = 0.46, P = 0.005). ...Th …
OCT showed the presence of intraretinal crystals in all patients. Patients with more severe thinning of the retina had worse visual a …