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Year Number of Results
1969 1
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34 results

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Page 1
Pathogenic roles of autoantibodies in systemic sclerosis: Current understandings in pathogenesis.
Senécal JL, Hoa S, Yang R, Koenig M. Senécal JL, et al. Among authors: koenig m. J Scleroderma Relat Disord. 2020 Jun;5(2):103-129. doi: 10.1177/2397198319870667. Epub 2019 Sep 9. J Scleroderma Relat Disord. 2020. PMID: 35382028 Free PMC article. Review.
The potential pathogenic role for autoantibodies in systemic sclerosis has captivated researchers for the past 40 years. ...Experimental data are difficult to interpret because high serum autoantibody levels may be due to polyclonal B-cell activation. …
The potential pathogenic role for autoantibodies in systemic sclerosis has captivated researchers for the past 40 years …
Anti-SMN autoantibodies in mixed connective tissue disease are associated with a severe systemic sclerosis phenotype.
El Kamouni H, S Jalaledin D, Albert A, Hoa S, Vo C, Bourré-Tessier J, Rich É, Goulet JR, Koenig M, Pérez G, Choi MY, Troyanov Y, Satoh M, Fritzler MJ, Senécal JL, Landon-Cardinal O. El Kamouni H, et al. Among authors: koenig m. RMD Open. 2023 Oct;9(4):e003431. doi: 10.1136/rmdopen-2023-003431. RMD Open. 2023. PMID: 37797966 Free PMC article.
OBJECTIVES: The survival of motor neuron (SMN) complex has an essential role in the assembly of small nuclear ribonucleoproteins (RNP). Recent reports have described autoantibodies (aAbs) to the SMN complex as novel biomarkers in anti-U1RNP+ myositis patients. ...Their pre …
OBJECTIVES: The survival of motor neuron (SMN) complex has an essential role in the assembly of small nuclear ribonucleoproteins (RNP). Rece …
Autoantibodies to a novel Rpp38 (Th/To) derived B-cell epitope are specific for systemic sclerosis and associate with a distinct clinical phenotype.
Koenig M, Bentow C, Satoh M, Fritzler MJ, Senécal JL, Mahler M. Koenig M, et al. Rheumatology (Oxford). 2019 Oct 1;58(10):1784-1793. doi: 10.1093/rheumatology/kez123. Rheumatology (Oxford). 2019. PMID: 31323671
OBJECTIVE: Detection of antinuclear antibodies and specific autoantibodies is important in the diagnosis and classification of SSc. ...CONCLUSION: A novel Rpp38 epitope holds promise to increase the sensitivity in the detection of anti-Th/To autoantibodies, thus enh …
OBJECTIVE: Detection of antinuclear antibodies and specific autoantibodies is important in the diagnosis and classification of SSc. . …
Predictive value of antinuclear autoantibodies: the lessons of the systemic sclerosis autoantibodies.
Koenig M, Dieudé M, Senécal JL. Koenig M, et al. Autoimmun Rev. 2008 Sep;7(8):588-93. doi: 10.1016/j.autrev.2008.06.010. Epub 2008 Jul 9. Autoimmun Rev. 2008. PMID: 18617021 Review.
Physicians who provide care to patients with systemic sclerosis (SSc, scleroderma) ask themselves several questions: Is SSc the correct diagnosis? ...In this brief review, we answer these questions by excerpting data from the literature focused on the 4 major SSc sp …
Physicians who provide care to patients with systemic sclerosis (SSc, scleroderma) ask themselves several questions: Is SSc th …
Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis.
Koenig M, Joyal F, Fritzler MJ, Roussin A, Abrahamowicz M, Boire G, Goulet JR, Rich E, Grodzicky T, Raymond Y, Senécal JL. Koenig M, et al. Arthritis Rheum. 2008 Dec;58(12):3902-12. doi: 10.1002/art.24038. Arthritis Rheum. 2008. PMID: 19035499 Free article.
OBJECTIVE: To identify in patients with Raynaud's phenomenon (RP) independent markers that predict progression to definite systemic sclerosis (SSc) and to determine in patients with progression to SSc the type and sequence of microvascular damage and its relationshi …
OBJECTIVE: To identify in patients with Raynaud's phenomenon (RP) independent markers that predict progression to definite systemic …
Left heart disease: a frequent cause of early pulmonary hypertension in systemic sclerosis, unrelated to elevated NT-proBNP levels or overt cardiac fibrosis but associated with increased levels of MR-proANP and MR-proADM: retrospective analysis of a French Canadian cohort.
Miller L, Chartrand S, Koenig M, Goulet JR, Rich É, Chin AS, Chartrand-Lefebvre C, Abrahamowicz M, Senécal JL, Grodzicky T. Miller L, et al. Among authors: koenig m. Scand J Rheumatol. 2014;43(4):314-23. doi: 10.3109/03009742.2013.854407. Epub 2014 Feb 6. Scand J Rheumatol. 2014. PMID: 25089008
OBJECTIVES: Pulmonary hypertension (PH) causes mortality in systemic sclerosis (SSc). Pulmonary arterial hypertension (PAH) and left heart disease (LHD) are frequent causes of PH. ...PAH was seen in 34% of patients. No association was found between the type of PH an …
OBJECTIVES: Pulmonary hypertension (PH) causes mortality in systemic sclerosis (SSc). Pulmonary arterial hypertension (PAH) an …
Autoantibodies to Mi-2 alpha and Mi-2 beta in patients with idiopathic inflammatory myopathy.
Richards M, García-De La Torre I, González-Bello YC, Vázquez-Del Mercado M, Andrade-Ortega L, Medrano-Ramírez G, Navarro-Zarza JE, Maradiaga-Ceceña M, Loyo E, Rojo-Mejía A, Gómez G, Seaman A, Fritzler MJ, Koenig M, Mahler M. Richards M, et al. Among authors: koenig m. Rheumatology (Oxford). 2019 Sep 1;58(9):1655-1661. doi: 10.1093/rheumatology/kez092. Rheumatology (Oxford). 2019. PMID: 30938432 Review.
CONCLUSION: Overall, good agreement was found between LIA and PMAT for anti-Mi-2 antibodies, which is important for the standardization of autoantibodies. Anti-Mi-2beta antibodies measured by PMAT tend be more highly associated with the clinical phenotype of DM....
CONCLUSION: Overall, good agreement was found between LIA and PMAT for anti-Mi-2 antibodies, which is important for the standardization of …
Early-Life Antibiotic Exposure Causes Intestinal Dysbiosis and Exacerbates Skin and Lung Pathology in Experimental Systemic Sclerosis.
Mehta H, Goulet PO, Mashiko S, Desjardins J, Pérez G, Koenig M, Senécal JL, Constante M, Santos MM, Sarfati M. Mehta H, et al. Among authors: koenig m. J Invest Dermatol. 2017 Nov;137(11):2316-2325. doi: 10.1016/j.jid.2017.06.019. Epub 2017 Jul 27. J Invest Dermatol. 2017. PMID: 28757138 Free article.
Patients with systemic sclerosis (SSc) display altered intestinal microbiota. However, the influence of intestinal dysbiosis on the development of experimental SSc remains unknown. ...
Patients with systemic sclerosis (SSc) display altered intestinal microbiota. However, the influence of intestinal dysbiosis o …
Lupus-like presentation of parvovirus B19 infection.
Sève P, Ferry T, Koenig M, Cathebras P, Rousset H, Broussolle C. Sève P, et al. Among authors: koenig m. Semin Arthritis Rheum. 2005 Feb;34(4):642-8. doi: 10.1016/j.semarthrit.2004.07.008. Semin Arthritis Rheum. 2005. PMID: 15692957 Review.
34 results