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Expert consensus on the systemic treatment of atopic dermatitis in special populations.
Adam DN, Gooderham MJ, Beecker JR, Hong CH, Jack CS, Jain V, Lansang P, Lynde CW, Papp KA, Prajapati VH, Turchin I, Yeung J. Adam DN, et al. J Eur Acad Dermatol Venereol. 2023 Jun;37(6):1135-1148. doi: 10.1111/jdv.18922. Epub 2023 Feb 8. J Eur Acad Dermatol Venereol. 2023. PMID: 36695072 Review.
We convened an expert panel consisting of 12 members to conduct a literature review and summarize relevant data related to six scenarios of clinical interest: comorbid asthma, ocular surface disease, history of cancer, past and ongoing infections of interest (including her …
We convened an expert panel consisting of 12 members to conduct a literature review and summarize relevant data related to six scenarios of …
Multiple chemical sensitivity: It's time to catch up to the science.
Molot J, Sears M, Anisman H. Molot J, et al. Neurosci Biobehav Rev. 2023 Aug;151:105227. doi: 10.1016/j.neubiorev.2023.105227. Epub 2023 May 10. Neurosci Biobehav Rev. 2023. PMID: 37172924 Free article. Review.
MCS is characterized by diverse features and common comorbidities, including fibromyalgia, cough hypersensitivity, asthma, and migraine, and stress/anxiety, with which the syndrome shares numerous neurobiological processes and altered functioning within diverse brain regio …
MCS is characterized by diverse features and common comorbidities, including fibromyalgia, cough hypersensitivity, asthma, and migrai …
Differential Diagnosis of Suspected Chronic Obstructive Pulmonary Disease Exacerbations in the Acute Care Setting: Best Practice.
Celli BR, Fabbri LM, Aaron SD, Agusti A, Brook RD, Criner GJ, Franssen FME, Humbert M, Hurst JR, Montes de Oca M, Pantoni L, Papi A, Rodriguez-Roisin R, Sethi S, Stolz D, Torres A, Vogelmeier CF, Wedzicha JA. Celli BR, et al. Am J Respir Crit Care Med. 2023 May 1;207(9):1134-1144. doi: 10.1164/rccm.202209-1795CI. Am J Respir Crit Care Med. 2023. PMID: 36701677 Free PMC article. Review.
Patients with COPD are usually older and frequently have concomitant chronic diseases, including heart failure, coronary artery disease, arrhythmias, interstitial lung diseases, bronchiectasis, asthma, anxiety, and depression, and are also at increased risk of developing p …
Patients with COPD are usually older and frequently have concomitant chronic diseases, including heart failure, coronary artery disease, arr …
Associations between mental and physical conditions in children and adolescents: An umbrella review.
Arrondo G, Solmi M, Dragioti E, Eudave L, Ruiz-Goikoetxea M, Ciaurriz-Larraz AM, Magallon S, Carvalho AF, Cipriani A, Fusar-Poli P, Larsson H, Correll CU, Cortese S. Arrondo G, et al. Neurosci Biobehav Rev. 2022 Jun;137:104662. doi: 10.1016/j.neubiorev.2022.104662. Epub 2022 Apr 12. Neurosci Biobehav Rev. 2022. PMID: 35427644 Free article. Review.
In analyses limited to the most rigorous estimates, we found evidence for the following associations: ADHD-asthma, ADHD-obesity, and depression-asthma. A transdiagnostic association was confirmed between asthma and anxiety/ASD/depression/bipolar disorder, bet …
In analyses limited to the most rigorous estimates, we found evidence for the following associations: ADHD-asthma, ADHD-obesity, and …
Early Diagnosis and Treatment of COPD and Asthma - A Randomized, Controlled Trial.
Aaron SD, Vandemheen KL, Whitmore GA, Bergeron C, Boulet LP, Côté A, McIvor RA, Penz E, Field SK, Lemière C, Mayers I, Bhutani M, Azher T, Lougheed MD, Gupta S, Ezer N, Licskai CJ, Hernandez P, Ainslie M, Alvarez GG, Mulpuru S; UCAP Investigators. Aaron SD, et al. N Engl J Med. 2024 May 19. doi: 10.1056/NEJMoa2401389. Online ahead of print. N Engl J Med. 2024. PMID: 38767248
BACKGROUND: Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respiratory symptoms remain largely untreated. ...RESULTS: Of 38,353 persons interviewed, 595 were found to have undiagnosed COPD or asthma a …
BACKGROUND: Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respirat …
Derivation and validation of the UCAP-Q case-finding questionnaire to detect undiagnosed asthma and COPD.
Huynh C, Whitmore GA, Vandemheen KL, FitzGerald JM, Bergeron C, Boulet LP, Cote A, Field SK, Penz E, McIvor RA, Lemière C, Gupta S, Mayers I, Bhutani M, Hernandez P, Lougheed MD, Licskai CJ, Azher T, Ainslie M, Fraser I, Mahdavian M, Alvarez GG, Kendzerska T, Aaron SD. Huynh C, et al. Eur Respir J. 2022 Sep 22;60(3):2103243. doi: 10.1183/13993003.03243-2021. Print 2022 Sep. Eur Respir J. 2022. PMID: 35332067 Free article.
Applied to the derivation sample (n=1615), the questionnaire yielded a sensitivity of 92% for asthma and 97% for COPD; specificity of 17%; and an AUC of 0.69 (95% CI 0.64-0.74) for asthma and 0.82 (95% CI 0.78-0.86) for COPD. ...AUCs for UCAP-Q were higher compared …
Applied to the derivation sample (n=1615), the questionnaire yielded a sensitivity of 92% for asthma and 97% for COPD; specificity of …
Barriers and Enablers to Objective Testing for Asthma and COPD in Primary Care: A Systematic Review Using the Theoretical Domains Framework.
Yamada J, Lam Shin Cheung J, Gagne M, Spiegel-Feld C, Aaron SD, FitzGerald JM, Gershon AS, Gupta S. Yamada J, et al. Chest. 2022 Apr;161(4):888-905. doi: 10.1016/j.chest.2021.10.030. Epub 2021 Nov 2. Chest. 2022. PMID: 34740591
BACKGROUND: Although guidelines long have recommended objective pulmonary function testing to diagnose asthma and COPD, many primary care patients receive a clinical diagnosis of asthma or COPD without objective testing. ...A theory-based, multifaceted intervention …
BACKGROUND: Although guidelines long have recommended objective pulmonary function testing to diagnose asthma and COPD, many primary …
Disease burden in individuals with symptomatic undiagnosed asthma or COPD.
Alhabeeb FF, Whitmore GA, Vandemheen KL, FitzGerald JM, Bergeron C, Lemière C, Boulet LP, Field SK, Penz E, McIvor RA, Gupta S, Mayers I, Bhutani M, Hernandez P, Lougheed D, Licskai CJ, Azher T, Cote A, Ainslie M, Fraser I, Mahdavian M, Aaron SD. Alhabeeb FF, et al. Respir Med. 2022 Aug-Sep;200:106917. doi: 10.1016/j.rmed.2022.106917. Epub 2022 Jul 3. Respir Med. 2022. PMID: 35850008
BACKGROUND: The actual burden of COPD and asthma may be much higher than appreciated, since a large proportion of individuals are not diagnosed. ...These results suggest that patients may benefit from early identification and treatment of undiagnosed asthma and COPD …
BACKGROUND: The actual burden of COPD and asthma may be much higher than appreciated, since a large proportion of individuals are not …
Impact of Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma on Symptoms, Quality of Life, Healthcare Use, and Work Productivity.
Gerstein E, Bierbrier J, Whitmore GA, Vandemheen KL, Bergeron C, Boulet LP, Cote A, Field SK, Penz E, McIvor RA, Lemière C, Gupta S, Hernandez P, Mayers I, Bhutani M, Lougheed MD, Licskai CJ, Azher T, Ezer N, Ainslie M, Alvarez GG, Mulpuru S, Aaron SD. Gerstein E, et al. Am J Respir Crit Care Med. 2023 Dec 15;208(12):1271-1282. doi: 10.1164/rccm.202307-1264OC. Am J Respir Crit Care Med. 2023. PMID: 37792953
Rationale: A significant proportion of individuals with chronic obstructive pulmonary disease (COPD) and asthma remain undiagnosed. Objectives: The objective of this study was to evaluate symptoms, quality of life, healthcare use, and work productivity in subjects with und …
Rationale: A significant proportion of individuals with chronic obstructive pulmonary disease (COPD) and asthma remain undiagnosed. O …
Neurological susceptibility to environmental exposures: pathophysiological mechanisms in neurodegeneration and multiple chemical sensitivity.
Molot J, Sears M, Marshall LM, Bray RI. Molot J, et al. Rev Environ Health. 2021 Sep 16;37(4):509-530. doi: 10.1515/reveh-2021-0043. Print 2022 Dec 16. Rev Environ Health. 2021. PMID: 34529912 Free article. Review.
Upregulation of chemosensitive TRPV1 and TRPA1 polymodal receptors has been observed in patients with neurodegeneration, and chemically sensitive individuals with asthma, migraine and MCS. In people with chemical sensitivity, these receptors are also sensitized, which is d …
Upregulation of chemosensitive TRPV1 and TRPA1 polymodal receptors has been observed in patients with neurodegeneration, and chemically sens …
54 results