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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1930 1
1947 1
1948 1
1954 1
1957 1
1961 1
1963 2
1964 4
1966 3
1968 4
1969 1
1970 2
1971 5
1972 2
1973 5
1974 7
1975 7
1976 8
1977 3
1978 5
1979 5
1980 5
1981 1
1982 2
1983 2
1984 4
1985 2
1986 5
1987 2
1988 6
1989 9
1990 9
1991 8
1992 12
1993 21
1994 23
1995 35
1996 23
1997 28
1998 11
1999 26
2000 27
2001 11
2002 12
2003 9
2004 10
2005 19
2006 15
2007 22
2008 8
2009 13
2010 24
2011 22
2012 27
2013 37
2014 27
2015 33
2016 31
2017 34
2018 33
2019 30
2020 40
2021 41
2022 37
2023 21
2024 20

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825 results

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Page 1
The Potentials of Methylene Blue as an Anti-Aging Drug.
Xue H, Thaivalappil A, Cao K. Xue H, et al. Cells. 2021 Dec 1;10(12):3379. doi: 10.3390/cells10123379. Cells. 2021. PMID: 34943887 Free PMC article. Review.
Methylene blue (MB), as the first fully man-made medicine, has a wide range of clinical applications. ...Mitochondrial dysfunction has been observed in systematic aging that affects many different tissues, including the brain and skin. This leads to increased …
Methylene blue (MB), as the first fully man-made medicine, has a wide range of clinical applications. ...Mitochondrial dysfunc …
Hydrogen sulfide intoxication induced brain injury and methylene blue.
Haouzi P, Sonobe T, Judenherc-Haouzi A. Haouzi P, et al. Neurobiol Dis. 2020 Jan;133:104474. doi: 10.1016/j.nbd.2019.05.013. Epub 2019 May 16. Neurobiol Dis. 2020. PMID: 31103557 Free article. Review.
Ion channels with critical implications for the cardiac and the brain functions appear to be affected very early during and following H(2)S exposure, an effect which is rapidly reversible during a light intoxication. ...This paper (1) presents and discusses the neurologica …
Ion channels with critical implications for the cardiac and the brain functions appear to be affected very early during and following …
From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue.
Tucker D, Lu Y, Zhang Q. Tucker D, et al. Mol Neurobiol. 2018 Jun;55(6):5137-5153. doi: 10.1007/s12035-017-0712-2. Epub 2017 Aug 24. Mol Neurobiol. 2018. PMID: 28840449 Free PMC article. Review.
Methylene blue (MB) is a well-established drug with a long history of use, owing to its diverse range of use and its minimal side effect profile. ...Mitochondrial dysfunction has been identified as a seemingly unifying pathological phenomenon across a wide range of …
Methylene blue (MB) is a well-established drug with a long history of use, owing to its diverse range of use and its minimal s …
Methylene blue and ifosfamide-induced encephalopathy: Myth or reality?
Abahssain H, Moukafih B, Essangri H, Mrabti H, Meddah B, Guessous F, Fadhil FZ, Souadka A, Errihani H. Abahssain H, et al. J Oncol Pharm Pract. 2021 Jan;27(1):143-149. doi: 10.1177/1078155220971843. Epub 2020 Nov 5. J Oncol Pharm Pract. 2021. PMID: 33153383
We subsequently conducted a literature review to determine the role of MB in IIE by searching PubMed using the terms "Methylene Blue" and "Ifosfamide". RESULTS: A total of 88 patients received ifosfamide, and four patients had IIE. ...Overall, 38 (65.5%) patients re …
We subsequently conducted a literature review to determine the role of MB in IIE by searching PubMed using the terms "Methylene Bl …
Methylene blue and its analogues as antidepressant compounds.
Delport A, Harvey BH, Petzer A, Petzer JP. Delport A, et al. Metab Brain Dis. 2017 Oct;32(5):1357-1382. doi: 10.1007/s11011-017-0081-6. Epub 2017 Jul 31. Metab Brain Dis. 2017. PMID: 28762173 Review.
Methylene Blue (MB) is considered to have diverse medical applications and is a well-described treatment for methemoglobinemias and ifosfamide-induced encephalopathy. ...
Methylene Blue (MB) is considered to have diverse medical applications and is a well-described treatment for methemoglobinemia …
Greenish-blue discoloration of the brain and heart after treatment with methylene blue.
Durão C, Pedrosa F, Dinis-Oliveira RJ. Durão C, et al. Forensic Sci Med Pathol. 2021 Mar;17(1):148-151. doi: 10.1007/s12024-020-00316-2. Epub 2020 Sep 17. Forensic Sci Med Pathol. 2021. PMID: 32940886
Greenish-blue discoloration of the brain and heart was observed during the autopsy of a 63-year-old woman who had been treated with methylene blue for septic shock following a traffic accident. ...Other clinically documented adverse effects of methy …
Greenish-blue discoloration of the brain and heart was observed during the autopsy of a 63-year-old woman who had been treated …
Neuroprotection by Methylene Blue in Cerebral Global Ischemic Injury Induced Blood-Brain Barrier Disruption and Brain Pathology: A Review.
Wiklund L, Sharma A, Sharma HS. Wiklund L, et al. CNS Neurol Disord Drug Targets. 2016;15(9):1181-1187. doi: 10.2174/1871527315666160915114516. CNS Neurol Disord Drug Targets. 2016. PMID: 27633785 Review.
Serious morbidity follows for many of the survivors and up to 16% of patients achieving restoration of spontaneous circulation develop brain death. Other survivors are left with persistent cognitive impairment such as memory and sensimotor deficits, reducing quality of lif …
Serious morbidity follows for many of the survivors and up to 16% of patients achieving restoration of spontaneous circulation develop br …
Methylene Blue: The Long and Winding Road From Stain to Brain: Part 2.
Howland RH. Howland RH. J Psychosoc Nurs Ment Health Serv. 2016 Oct 1;54(10):21-26. doi: 10.3928/02793695-20160920-04. J Psychosoc Nurs Ment Health Serv. 2016. PMID: 27699422
Methylene blue is a cationic thiazine dye with redox-cycling properties and a selective affinity for the nervous system. ...Investigations of methylene blue were instrumental in the serendipitous development of phenothiazine antipsychotic drugs. ...
Methylene blue is a cationic thiazine dye with redox-cycling properties and a selective affinity for the nervous system. ...In …
Methylene Blue: The Long and Winding Road from Stain to Brain: Part 1.
Howland RH. Howland RH. J Psychosoc Nurs Ment Health Serv. 2016 Sep 1;54(9):21-4. doi: 10.3928/02793695-20160818-01. J Psychosoc Nurs Ment Health Serv. 2016. PMID: 27576224
Methylene blue, first discovered and used as a dye in the textile industry, has long been used for biological staining in histology, bacteriology, and hematology. Because of its unique physiochemical properties, it was the first synthetic drug used in medicine, havi …
Methylene blue, first discovered and used as a dye in the textile industry, has long been used for biological staining in hist …
Role of Methylene Blue in Trauma Neuroprotection and Neuropsychiatric Diseases.
Batista-Filho MM, Kandratavicius L, Nunes EA, Tumas V, Colli BO, Hallak JE, Maia-de-Oliveira JP, Evora PR. Batista-Filho MM, et al. CNS Neurol Disord Drug Targets. 2016;15(8):976-986. doi: 10.2174/1871527315666160720120326. CNS Neurol Disord Drug Targets. 2016. PMID: 27450870 Review.
The aim of the present review is to assess current literature on the possible role of methylene blue (MB) in the central nervous system due to the increasing number of citations in spite of the few articles available on the subject which suggest growing interest in …
The aim of the present review is to assess current literature on the possible role of methylene blue (MB) in the central nervo …
825 results