Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1970 1
1975 2
1978 1
1988 1
1995 1
1996 1
2003 1
2006 2
2007 2
2008 1
2011 2
2012 2
2013 1
2014 1
2016 2
2019 1
2020 3
2021 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

27 results

Results by year

Filters applied: . Clear all
Page 1
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury.
Islam MN, Das SR, Emin MT, Wei M, Sun L, Westphalen K, Rowlands DJ, Quadri SK, Bhattacharya S, Bhattacharya J. Islam MN, et al. Among authors: rowlands dj. Nat Med. 2012 Apr 15;18(5):759-65. doi: 10.1038/nm.2736. Nat Med. 2012. PMID: 22504485 Free PMC article.
Bone marrow-derived stromal cells (BMSCs) protect against acute lung injury (ALI). To determine the role of BMSC mitochondria in this protection, we airway-instilled mice first with lipopolysaccharide (LPS) and then with either mouse BMSCs (mBMSCs) or human BMSCs (hBMSCs). …
Bone marrow-derived stromal cells (BMSCs) protect against acute lung injury (ALI). To determine the role of BMSC mitochondria in this …
Mitochondria dysfunction: A novel therapeutic target in pathological lung remodeling or bystander?
Rowlands DJ. Rowlands DJ. Pharmacol Ther. 2016 Oct;166:96-105. doi: 10.1016/j.pharmthera.2016.06.019. Epub 2016 Jul 1. Pharmacol Ther. 2016. PMID: 27373853 Review.
Recent mechanistic insights have established links between mitochondrial dysfunction or aberrant biogenesis and the pathogenesis of chronic respiratory diseases through playing a causative role in structural remodeling of the lung. The aim here is to discuss the case for a …
Recent mechanistic insights have established links between mitochondrial dysfunction or aberrant biogenesis and the pathogenesis of chronic …
Microphysiological lung models to evaluate the safety of new pharmaceutical modalities: a biopharmaceutical perspective.
Ainslie GR, Davis M, Ewart L, Lieberman LA, Rowlands DJ, Thorley AJ, Yoder G, Ryan AM. Ainslie GR, et al. Among authors: rowlands dj. Lab Chip. 2019 Sep 27;19(19):3152-3161. doi: 10.1039/c9lc00492k. Lab Chip. 2019. PMID: 31469131 Review.
The lung is a complex organ; it is both the initial barrier for inhaled agents and the site of metabolism and therapeutic effect for a subset of systemically administered drugs. Comprised of more than 40 cell types that are responsible for various important functions, the …
The lung is a complex organ; it is both the initial barrier for inhaled agents and the site of metabolism and therapeutic effect for …
Activation of endothelial nitric oxide synthase by dietary isoflavones: role of NO in Nrf2-mediated antioxidant gene expression.
Mann GE, Rowlands DJ, Li FY, de Winter P, Siow RC. Mann GE, et al. Among authors: rowlands dj. Cardiovasc Res. 2007 Jul 15;75(2):261-74. doi: 10.1016/j.cardiores.2007.04.004. Epub 2007 Apr 6. Cardiovasc Res. 2007. PMID: 17498676 Review.
The endothelium plays a key role in the maintenance of vascular homeostasis, and increased oxidative stress in vascular disease leads to reduced nitric oxide bioavailability and impaired endothelium-dependent relaxation of resistance vessels. ...In this revie …
The endothelium plays a key role in the maintenance of vascular homeostasis, and increased oxidative stress in vascular diseas …
Cardiovascular targets for estrogens and phytoestrogens: transcriptional regulation of nitric oxide synthase and antioxidant defense genes.
Siow RC, Li FY, Rowlands DJ, de Winter P, Mann GE. Siow RC, et al. Among authors: rowlands dj. Free Radic Biol Med. 2007 Apr 1;42(7):909-25. doi: 10.1016/j.freeradbiomed.2007.01.004. Epub 2007 Jan 8. Free Radic Biol Med. 2007. PMID: 17349919 Review.
We review the molecular mechanisms (nongenomic vs genomic) by which estrogens, isoflavones, and polyphenols stimulate intracellular signal transduction pathways involved in endothelial nitric oxide production and transcriptional activation of antioxidant defense genes in vascu …
We review the molecular mechanisms (nongenomic vs genomic) by which estrogens, isoflavones, and polyphenols stimulate intracellular signal t …
Safety and efficacy of the cystic fibrosis transmembrane conductance regulator potentiator icenticaftor (QBW251).
Kazani S, Rowlands DJ, Bottoli I, Milojevic J, Alcantara J, Jones I, Kulmatycki K, Machineni S, Mostovy L, Nicholls I, Nick JA, Rowe SM, Simmonds NJ, Vegesna R, Verheijen J, Danahay H, Gosling M, Ayalavajjala PS, Salman M, Strieter R. Kazani S, et al. Among authors: rowlands dj. J Cyst Fibros. 2021 Mar;20(2):250-256. doi: 10.1016/j.jcf.2020.11.002. Epub 2020 Dec 6. J Cyst Fibros. 2021. PMID: 33293212 Free PMC article.
Efficacy was assessed in adult CF patients with 1 pre-specified CFTR Class III or IV mutation (150 and 450 mg bid), or homozygous for F508del mutation (450 mg bid). Primary efficacy endpoint was change from baseline in lung clearance index (LCI(2.5)). Secondary endpoints i …
Efficacy was assessed in adult CF patients with 1 pre-specified CFTR Class III or IV mutation (150 and 450 mg bid), or homozygous for F508de …
MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.
Rothman AM, Arnold ND, Pickworth JA, Iremonger J, Ciuclan L, Allen RM, Guth-Gundel S, Southwood M, Morrell NW, Thomas M, Francis SE, Rowlands DJ, Lawrie A. Rothman AM, et al. Among authors: rowlands dj. J Clin Invest. 2016 Jul 1;126(7):2495-508. doi: 10.1172/JCI83361. Epub 2016 May 23. J Clin Invest. 2016. PMID: 27214554 Free PMC article.
Sex-dependent influence of endogenous estrogen in pulmonary hypertension.
Mair KM, Wright AF, Duggan N, Rowlands DJ, Hussey MJ, Roberts S, Fullerton J, Nilsen M, Loughlin L, Thomas M, MacLean MR. Mair KM, et al. Among authors: rowlands dj. Am J Respir Crit Care Med. 2014 Aug 15;190(4):456-67. doi: 10.1164/rccm.201403-0483OC. Am J Respir Crit Care Med. 2014. PMID: 24956156 Free PMC article.
To verify this effect was caused by reduced estrogenic activity we confirmed that in hypoxic mice inhibition of estrogen receptor alpha also has a therapeutic effect specifically in females. Female rodent lung displays increased aromatase and decreased bone morphogenetic p …
To verify this effect was caused by reduced estrogenic activity we confirmed that in hypoxic mice inhibition of estrogen receptor alpha also …
Continuous, Automated Breathing Rate and Body Motion Monitoring of Rats With Paraquat-Induced Progressive Lung Injury.
Baran SW, Gupta AD, Lim MA, Mathur A, Rowlands DJ, Schaevitz LR, Shanmukhappa SK, Walker DB. Baran SW, et al. Among authors: rowlands dj. Front Physiol. 2020 Oct 16;11:569001. doi: 10.3389/fphys.2020.569001. eCollection 2020. Front Physiol. 2020. PMID: 33178039 Free PMC article.
We investigated whether continuous, direct monitoring of breathing rate and body motion in animals in the home cage using the Vum Digital Smart House can complement standard measurements in enabling more granular detection of the onset and severity of physiologic events related t …
We investigated whether continuous, direct monitoring of breathing rate and body motion in animals in the home cage using the Vum Digital Sm …
27 results