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Evaluation of urinary acetaminophen metabolites and its association with the genetic polymorphisms of the metabolising enzymes, and serum acetaminophen concentrations in preterm neonates with patent ductus arteriosus.
Sridharan K, Al Jufairi M, Al Ansari E, Jasim A, Eltayeb Diab D, Al Marzooq R, Al Madhoob A. Sridharan K, et al. Xenobiotica. 2021 Nov;51(11):1335-1342. doi: 10.1080/00498254.2021.1982070. Epub 2021 Sep 28. Xenobiotica. 2021. PMID: 34529545
Predominant metabolites of acetaminophen in preterm neonates vary from that of adults; and the drug is predominantly metabolised by conjugation and partly by Cytochrome P450 (CYP) enzymes.We carried out the present study to identify the principal urine metabolites of acetaminophe …
Predominant metabolites of acetaminophen in preterm neonates vary from that of adults; and the drug is predominantly metabolised by conjugat …
Isotretinoin treatment alters steroid metabolism in women with acne.
Rademaker M, Wallace M, Cunliffe W, Simpson NB. Rademaker M, et al. Br J Dermatol. 1991 Apr;124(4):361-4. doi: 10.1111/j.1365-2133.1991.tb00598.x. Br J Dermatol. 1991. PMID: 1827343
Serum concentrations of dehydroepiandrosterone sulphate (DHAS), androstenedione (A2), and free androgen index (FAI) were not significantly altered. ...Although pretreatment levels of urinary steroid metabolites were not abnormal, the ratios of the 5 al …
Serum concentrations of dehydroepiandrosterone sulphate (DHAS), androstenedione (A2), and free androgen index (FAI) were not s …
Urinary and serum steroid concentrations in the management of congenital adrenal hyperplasia. Lack of physiologic correlations.
Hendricks SA, Lippe BM, Kaplan SA, Lavin N, Mayes DM. Hendricks SA, et al. Am J Dis Child. 1982 Mar;136(3):229-32. doi: 10.1001/archpedi.1982.03970390043014. Am J Dis Child. 1982. PMID: 7064949
Serum concentrations of 17-hydroxyprogesterone, dehydroepiandrosterone, dehydroepiandrosterone sulfate, progesterone, testosterone, and androstenedione and 24-hour excretion of 17-ketosteroids and pregnanetriol were measured serially in 18 children with congenita …
Serum concentrations of 17-hydroxyprogesterone, dehydroepiandrosterone, dehydroepiandrosterone sulfate, progesterone, testoste …