Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1994 2
1996 4
1997 1
1998 2
2000 2
2001 3
2002 3
2003 3
2004 5
2005 2
2006 4
2007 1
2008 2
2009 2
2010 3
2011 5
2012 5
2013 4
2014 4
2015 2
2016 3
2017 3
2018 1
2019 2
2020 4
2021 7
2022 3
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

73 results

Results by year

Filters applied: . Clear all
Page 1
Antituberculosis drug-induced hepatitis: risk factors, prevention and management.
Hussain Z, Kar P, Husain SA. Hussain Z, et al. Indian J Exp Biol. 2003 Nov;41(11):1226-32. Indian J Exp Biol. 2003. PMID: 15332488 Review.
Deficiency of GST activity, because of homozygous null mutations at GSTM1 and GSTT1 loci, may modulate susceptibility to drug and xenobiotic-induced hepatotoxicity. Polymorphisms at GSTM1, GSTT1 and NAT2 loci had been linked to various forms of liver injury, including hepa …
Deficiency of GST activity, because of homozygous null mutations at GSTM1 and GSTT1 loci, may modulate susceptibility to drug and xenobio …
The blood-brain barrier and cancer: transporters, treatment, and Trojan horses.
Deeken JF, Löscher W. Deeken JF, et al. Clin Cancer Res. 2007 Mar 15;13(6):1663-74. doi: 10.1158/1078-0432.CCR-06-2854. Clin Cancer Res. 2007. PMID: 17363519 Review.
Recent evidence has shown that a critical aspect of this barrier is composed of xenobiotic transporters which extrude substrates from the brain into the cerebrospinal fluid and systemic circulation. ...The responsiveness of brain tumors to systemic treatment found in past …
Recent evidence has shown that a critical aspect of this barrier is composed of xenobiotic transporters which extrude substrates from …
Drug-induced methaemoglobinaemia. Treatment issues.
Coleman MD, Coleman NA. Coleman MD, et al. Drug Saf. 1996 Jun;14(6):394-405. doi: 10.2165/00002018-199614060-00005. Drug Saf. 1996. PMID: 8828017 Review.
The clinical consequences of methaemoglobinaemia are related to the blood level of methaemoglobin; dyspnoea, nausea and tachycardia occur at methaemoglobin levels of > or = 30%, while lethargy, stupor and deteriorating consciousness occur as methaemoglobin levels approa …
The clinical consequences of methaemoglobinaemia are related to the blood level of methaemoglobin; dyspnoea, nausea and tachycardia o …
Evaluation of Genetic Polymorphisms of N-acetyltransferase 2 and Relation with Chronic Myeloid Leukemia.
Tebien EM, Khalil HB, Mills J, Elderdery AY. Tebien EM, et al. Asian Pac J Cancer Prev. 2020 Dec 1;21(12):3711-3717. doi: 10.31557/APJCP.2020.21.12.3711. Asian Pac J Cancer Prev. 2020. PMID: 33369472 Free PMC article.
OBJECTIVES: The N-Acetyltransferase 2 (NAT2) gene encodes a key enzyme involved in xenobiotic metabolism, which contributes to the detoxification of numerous cancer therapy-induced products. ...
OBJECTIVES: The N-Acetyltransferase 2 (NAT2) gene encodes a key enzyme involved in xenobiotic metabolism, which contributes to the de …
Occupational risk assessment of exposure to metals in chrome plating workers.
Muller CD, Garcia SC, Brucker N, Goethel G, Sauer E, Lacerda LM, Oliveira E, Trombini TL, Machado AB, Pressotto A, Rech VC, Klauck CR, Basso da Silva L, Gioda A, Feksa LR. Muller CD, et al. Drug Chem Toxicol. 2022 Mar;45(2):560-567. doi: 10.1080/01480545.2020.1731527. Epub 2020 Feb 27. Drug Chem Toxicol. 2022. PMID: 32106715
Inhalation of xenobiotics during manufacture process in chrome plating bath produce hazards to workers' health. ...Biological monitoring was performed through quantification of Cr, Pb, As, Ni, and V in blood by ICP-MS in 50 male chrome-plating workers from the expos …
Inhalation of xenobiotics during manufacture process in chrome plating bath produce hazards to workers' health. ...Biological monitor …
Blood-Brain Barrier (BBB)-Crossing Strategies for Improved Treatment of CNS Disorders.
Zhang W. Zhang W. Handb Exp Pharmacol. 2024;284:213-230. doi: 10.1007/164_2023_689. Handb Exp Pharmacol. 2024. PMID: 37528323
Blood-brain barrier (BBB) is a special biological property of the brain neurovascular unit (including brain microvessels and capillaries), which facilitates the transport of nutrients into the central nervous system (CNS) and exchanges metabolites but restricts passage of …
Blood-brain barrier (BBB) is a special biological property of the brain neurovascular unit (including brain microvessels and capillar …
The Impact of P-Glycoprotein on Opioid Analgesics: What's the Real Meaning in Pain Management and Palliative Care?
Coluzzi F, Scerpa MS, Rocco M, Fornasari D. Coluzzi F, et al. Int J Mol Sci. 2022 Nov 16;23(22):14125. doi: 10.3390/ijms232214125. Int J Mol Sci. 2022. PMID: 36430602 Free PMC article. Review.
Opioids are widely used in cancer and non-cancer pain management. However, many transporters at the blood-brain barrier (BBB), such as P-glycoprotein (P-gp, ABCB1/MDR1), may impair their delivery to the brain, thus leading to opioid tolerance. ...The role of P-gp in drug-d …
Opioids are widely used in cancer and non-cancer pain management. However, many transporters at the blood-brain barrier (BBB), such a …
Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management.
Pagano G, Tiano L, Pallardó FV, Lyakhovich A, Mukhopadhyay SS, Di Bartolomeo P, Zatterale A, Trifuoggi M. Pagano G, et al. Redox Biol. 2021 Apr;40:101860. doi: 10.1016/j.redox.2021.101860. Epub 2021 Jan 7. Redox Biol. 2021. PMID: 33445068 Free PMC article. Review.
The former definition has built up the grounds for FA diagnosis as excess sensitivity of patients' cells to xenobiotics as diepoxybutane and mitomycin C, resulting in typical chromosomal abnormalities. ...
The former definition has built up the grounds for FA diagnosis as excess sensitivity of patients' cells to xenobiotics as diepoxybut …
Genotoxic risk assessment and mechanism of DNA damage induced by phthalates and their metabolites in human peripheral blood mononuclear cells.
Sicińska P, Mokra K, Wozniak K, Michałowicz J, Bukowska B. Sicińska P, et al. Sci Rep. 2021 Jan 18;11(1):1658. doi: 10.1038/s41598-020-79932-5. Sci Rep. 2021. PMID: 33462290 Free PMC article.
The human genome is persistently exposed to damage caused by xenobiotics, therefore the assessment of genotoxicity of substances having a direct contact with humans is of importance. ...We have assessed the genotoxic potential of selected phthalates and mechanism of their …
The human genome is persistently exposed to damage caused by xenobiotics, therefore the assessment of genotoxicity of substances havi …
GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: a systematic review and meta-analysis.
Xiao Q, Deng D, Li H, Ye F, Huang L, Zhang B, Ye B, Mo Z, Yang X, Liu Z. Xiao Q, et al. Ann Hematol. 2014 Aug;93(8):1381-90. doi: 10.1007/s00277-014-2050-z. Epub 2014 Mar 29. Ann Hematol. 2014. PMID: 24994605 Review.
Glutathione S-transferases (GSTs) contribute to the metabolism of different xenobiotics and anticancer drugs and confer protection against oxidative stress thus may influence the treatment outcome of acute myeloid leukemia (AML). ...
Glutathione S-transferases (GSTs) contribute to the metabolism of different xenobiotics and anticancer drugs and confer protection ag …
73 results