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Attitudes Toward Genetic Testing for Celiac Disease.
Roy A, Pallai M, Lebwohl B, Taylor AK, Green PH. Roy A, et al. J Genet Couns. 2016 Apr;25(2):270-8. doi: 10.1007/s10897-015-9867-z. Epub 2015 Aug 2. J Genet Couns. 2016. PMID: 26233331 Free PMC article.
HLA molecular typing for celiac disease (CD) is a genetic test with a high negative predictive value. ...On multivariable analysis, adjusting for age, sex, education, marital status, region of residence, and having children, college-education (OR 2.05, 95 % CI: 1.33 …
HLA molecular typing for celiac disease (CD) is a genetic test with a high negative predictive value. ...On multivariable anal …
Accuracy of Serological Screening for the Diagnosis of Celiac Disease in Type 1 Diabetes Children.
Girard C, De Percin A, Morin C, Talvard M, Fortenfant F, Congy-Jolivet N, Le Tallec C, Olives JP, Mas E. Girard C, et al. Medicina (Kaunas). 2023 Jul 18;59(7):1321. doi: 10.3390/medicina59071321. Medicina (Kaunas). 2023. PMID: 37512132 Free PMC article.
Background and Objectives: Patients with type 1 diabetes (T1D) are considered at high-risk for developing celiac disease (CD). The purpose of our study was to determine the prevalence of CD among children who were followed in our unit for T1D using the latest ESPGHA …
Background and Objectives: Patients with type 1 diabetes (T1D) are considered at high-risk for developing celiac disease (CD). …
Celiac disease in pediatric patients with autoimmune hepatitis: etiology, diagnosis, and management.
Panetta F, Nobili V, Sartorelli MR, Papa RE, Ferretti F, Alterio A, Diamanti A. Panetta F, et al. Paediatr Drugs. 2012 Feb 1;14(1):35-41. doi: 10.2165/11593150-000000000-00000. Paediatr Drugs. 2012. PMID: 22149550 Review.
Celiac disease (CD) is defined as a permanent intolerance to ingested wheat gliadins and other cereal prolamins, occurring in genetically susceptible people. ...The only currently available treatment for CD is the GFD and the supportive nutritional care …
Celiac disease (CD) is defined as a permanent intolerance to ingested wheat gliadins and other cereal prolamins, occurring in …
Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases.
Anaya JM, Kim-Howard X, Prahalad S, Cherñavsky A, Cañas C, Rojas-Villarraga A, Bohnsack J, Jonsson R, Bolstad AI, Brun JG, Cobb B, Moser KL, James JA, Harley JB, Nath SK. Anaya JM, et al. Autoimmun Rev. 2012 Feb;11(4):276-80. doi: 10.1016/j.autrev.2011.07.007. Epub 2011 Aug 5. Autoimmun Rev. 2012. PMID: 21840425 Free PMC article. Review.
Many autoimmune diseases (ADs) share similar underlying pathology and have a tendency to cluster within families, supporting the involvement of shared susceptibility genes. To date, most of the genetic variants associated with systemic lupus erythematosus (SLE) suscepti …
Many autoimmune diseases (ADs) share similar underlying pathology and have a tendency to cluster within families, supporting the involvement …
Pharmacotherapy and management strategies for coeliac disease.
Donnelly SC, Ellis HJ, Ciclitira PJ. Donnelly SC, et al. Expert Opin Pharmacother. 2011 Aug;12(11):1731-44. doi: 10.1517/14656566.2011.592140. Epub 2011 Jul 1. Expert Opin Pharmacother. 2011. PMID: 21718231 Review.
AREAS COVERED: This review covers the current treatment options available and discusses novel emerging therapies for coeliac disease. EXPERT OPINION: Novel therapies are still in early stages of development and therefore, at present, a gluten-free diet …
AREAS COVERED: This review covers the current treatment options available and discusses novel emerging therapies for coeliac …
"Geographical distribution of risk genotypes in pediatric patients with celiac disease in Spain".
Sánchez-Valverde F, Martínez-Ojinaga E, Donat E, Bodas A, Bandrés E, Torres R, Ibáñez B, Cilleruelo ML, Castillejo G, Pérez-Solis D, Ochoa C, Eizaguirre FJ, García S, García JI, Barrio J, Vecino R, Miranda MDC, Juste M, Salazar JC, Armas H, Ortigosa L, Urruzuno P, García Z, Balmaseda E, Martinez-Costa C, La Orden E, Codoñer P, Roca A, Trillo C, Sebastian M, García R, Peña-Quintana L, Barros P, Soria M, García R, Pérez-Moneo B, Polanco I, Ribes C, Román E; Collaborators. Sánchez-Valverde F, et al. Hum Immunol. 2023 Apr;84(4):290-295. doi: 10.1016/j.humimm.2023.01.010. Epub 2023 Feb 28. Hum Immunol. 2023. PMID: 36858916
Celiac disease is strongly associated with HLA DQ, specifically with haplotypes. ...The distribution of these risk haplotypes in patients with celiac disease is different in the geographical areas investigated. ...
Celiac disease is strongly associated with HLA DQ, specifically with haplotypes. ...The distribution of these risk haplotypes …
Features of ZED1227: The First-In-Class Tissue Transglutaminase Inhibitor Undergoing Clinical Evaluation for the Treatment of Celiac Disease.
Büchold C, Hils M, Gerlach U, Weber J, Pelzer C, Heil A, Aeschlimann D, Pasternack R. Büchold C, et al. Cells. 2022 May 17;11(10):1667. doi: 10.3390/cells11101667. Cells. 2022. PMID: 35626704 Free PMC article.
The compound selectively binds to the active state of TG2, forming a stable covalent bond with the cysteine in its catalytic center. The molecule was designed for the treatment of celiac disease. Celiac disease is an autoimmune-mediated chronic inflamm …
The compound selectively binds to the active state of TG2, forming a stable covalent bond with the cysteine in its catalytic center. The mol …
Serologic screening and genetic testing among brazilian patients with celiac disease and their first degree relatives.
Martins Rde C, Gandolfi L, Modelli IC, Almeida RC, Castro LC, Pratesi R. Martins Rde C, et al. Arq Gastroenterol. 2010 Jul-Sep;47(3):257-62. doi: 10.1590/s0004-28032010000300009. Arq Gastroenterol. 2010. PMID: 21140086 Free article.
CONTEXT: Celiac disease susceptibility has been shown to be associated with the HLA alleles DQA1*0501 and DQB1*0201 (together encoding the DQ2 heterodimer) that are present in practically all celiac disease patients. ...Fourteen (6.7%) new cases …
CONTEXT: Celiac disease susceptibility has been shown to be associated with the HLA alleles DQA1*0501 and DQB1*0201 (to …
HLA genotypes and the increased incidence of coeliac disease in Sweden.
Ploski R, Ascher H, Sollid LM. Ploski R, et al. Scand J Gastroenterol. 1996 Nov;31(11):1092-7. doi: 10.3109/00365529609036892. Scand J Gastroenterol. 1996. PMID: 8938902
BACKGROUND: A strong increase of childhood coeliac disease (CD) was found in Sweden concurrently with changes in the infant feeding pattern. ...CONCLUSIONS: The results suggest that Swedish CD patients do not differ in genetic susceptibility compared with oth …
BACKGROUND: A strong increase of childhood coeliac disease (CD) was found in Sweden concurrently with changes in the infant fe …