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Year Number of Results
1987 1
1993 1
2001 1
2007 1
2009 1
2010 2
2011 3
2012 2
2013 2
2014 1
2015 1
2016 2
2017 1
2020 2
2021 1
2023 1
2024 0

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22 results

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Page 1
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases.
Wang Y, Hu J, Wu S, Fleishman JS, Li Y, Xu Y, Zou W, Wang J, Feng Y, Chen J, Wang H. Wang Y, et al. Signal Transduct Target Ther. 2023 Dec 10;8(1):449. doi: 10.1038/s41392-023-01720-0. Signal Transduct Target Ther. 2023. PMID: 38072908 Free PMC article. Review.
Accumulating studies indicate that epigenetic modifications can transcriptionally and translationally determine cancer cell vulnerability to ferroptosis and that ferroptosis functions as a driver in nervous system diseases (NSDs), cardiovascular diseases (CVDs), liv …
Accumulating studies indicate that epigenetic modifications can transcriptionally and translationally determine cancer cell vulnerability to …
Nephrotoxicity as a Complication of Chemotherapy and Immunotherapy in the Treatment of Colorectal Cancer, Melanoma and Non-Small Cell Lung Cancer.
Jagieła J, Bartnicki P, Rysz J. Jagieła J, et al. Int J Mol Sci. 2021 Apr 28;22(9):4618. doi: 10.3390/ijms22094618. Int J Mol Sci. 2021. PMID: 33924827 Free PMC article. Review.
Acute kidney injury is a common complication of many medical procedures, including those used in cancer treatment. Both chemotherapy and immunotherapy may result in deterioration of kidney function, which may lead to an increase in mortality among patients with canc …
Acute kidney injury is a common complication of many medical procedures, including those used in cancer treatment. Both chemotherapy …
Nephrotoxicity of anticancer treatment.
Malyszko J, Kozlowska K, Kozlowski L, Malyszko J. Malyszko J, et al. Nephrol Dial Transplant. 2017 Jun 1;32(6):924-936. doi: 10.1093/ndt/gfw338. Nephrol Dial Transplant. 2017. PMID: 28339935 Review.
Cytotoxic agents can cause nephrotoxicity by a variety of mechanisms. The most nephrotoxic chemotherapeutic drug is cisplatin, which is often associated with acute kidney injury. ...The aim of this review is to discuss the issue of nephrotoxicity associated w …
Cytotoxic agents can cause nephrotoxicity by a variety of mechanisms. The most nephrotoxic chemotherapeutic drug is cisplatin, …
The link between kidney disease and cancer: complications and treatment.
Malyszko J, Tesarova P, Capasso G, Capasso A. Malyszko J, et al. Lancet. 2020 Jul 25;396(10246):277-287. doi: 10.1016/S0140-6736(20)30540-7. Lancet. 2020. PMID: 32711803 Review.
Acute and chronic kidney disease encompasses a complex set of diseases that can both lead to, and result from, cancer. In particular, kidney disease can arise from the use of chemotherapeutic agents. ...
Acute and chronic kidney disease encompasses a complex set of diseases that can both lead to, and result from, cancer. In part …
Toxicities of targeted therapy and their management in kidney cancer.
Di Lorenzo G, Porta C, Bellmunt J, Sternberg C, Kirkali Z, Staehler M, Joniau S, Montorsi F, Buonerba C. Di Lorenzo G, et al. Eur Urol. 2011 Apr;59(4):526-40. doi: 10.1016/j.eururo.2011.01.002. Epub 2011 Jan 14. Eur Urol. 2011. PMID: 21277078 Review.
Oncologists must be familiar with the management of toxicity that these biologic agents cause, as such toxicity is different from that of conventional chemotherapeutic agents. OBJECTIVE: To describe toxic effects associated with targeted therapy of mRCC and their pr …
Oncologists must be familiar with the management of toxicity that these biologic agents cause, as such toxicity is different from that of co …
Treatment of metastatic renal cell carcinoma and renal pelvic cancer.
Tanji N, Yokoyama M. Tanji N, et al. Clin Exp Nephrol. 2011 Jun;15(3):331-338. doi: 10.1007/s10157-011-0438-9. Epub 2011 Apr 12. Clin Exp Nephrol. 2011. PMID: 21479988 Review.
Because renal pelvic cancer has many similarities in pathogenesis with urinary bladder cancer, the same chemotherapeutic regimen is often proposed for patients with metastatic renal pelvic cancer. ...To select new therapeutic modalities, a more profound understandin …
Because renal pelvic cancer has many similarities in pathogenesis with urinary bladder cancer, the same chemotherapeutic regimen is o …
Best practices in the management of toxicities related to anti-EGFR agents for metastatic colorectal cancer.
Ouwerkerk J, Boers-Doets C. Ouwerkerk J, et al. Eur J Oncol Nurs. 2010 Sep;14(4):337-49. doi: 10.1016/j.ejon.2010.03.004. Epub 2010 May 23. Eur J Oncol Nurs. 2010. PMID: 20580896 Review.
We reviewed the literature regarding the signs and symptoms, assessment of severity, and strategies available to prevent and manage adverse events associated with these agents. KEY RESULTS: This class of therapeutics is associated with an overall acceptable adverse event p …
We reviewed the literature regarding the signs and symptoms, assessment of severity, and strategies available to prevent and manage adverse …
An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures.
Dugbartey GJ, Peppone LJ, de Graaf IA. Dugbartey GJ, et al. Toxicology. 2016 Sep 14;371:58-66. doi: 10.1016/j.tox.2016.10.001. Epub 2016 Oct 4. Toxicology. 2016. PMID: 27717837 Free PMC article. Review.
Experimental studies show cisplatin generates reactive oxygen species, which impair the cell's antioxidant defense system, causing oxidative stress and potentiating injury, thereby culminating in kidney and heart failure. Understanding the molecular mechanisms of cisplatin …
Experimental studies show cisplatin generates reactive oxygen species, which impair the cell's antioxidant defense system, causing oxidative …
Cytotoxic chemotherapy in the treatment of advanced renal cell carcinoma in the era of targeted therapy.
Diamond E, Molina AM, Carbonaro M, Akhtar NH, Giannakakou P, Tagawa ST, Nanus DM. Diamond E, et al. Crit Rev Oncol Hematol. 2015 Dec;96(3):518-26. doi: 10.1016/j.critrevonc.2015.08.007. Epub 2015 Aug 13. Crit Rev Oncol Hematol. 2015. PMID: 26321263 Review.
METHODS: We reviewed the available literature for published clinical trials incorporating traditional chemotherapeutic agents in the treatment of mRCC. These papers were identified through a Medline search and were included if they employed at least one chemotherapeutic …
METHODS: We reviewed the available literature for published clinical trials incorporating traditional chemotherapeutic agents in the …
Novel approaches in the treatment of lupus nephritis.
Illei GG, Czirják L. Illei GG, et al. Expert Opin Investig Drugs. 2001 Jun;10(6):1117-30. doi: 10.1517/13543784.10.6.1117. Expert Opin Investig Drugs. 2001. PMID: 11772239 Review.
The auto-antibodies form immune complexes with their respective auto-antigens, which in turn deposit in sites such as the kidney and initiate a destructive inflammatory reaction. Lupus nephritis can be managed successfully in the majority of cases; however, the most widely …
The auto-antibodies form immune complexes with their respective auto-antigens, which in turn deposit in sites such as the kidney and …
22 results