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Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment.
Esmaeili Y, Yarjanli Z, Pakniya F, Bidram E, Łos MJ, Eshraghi M, Klionsky DJ, Ghavami S, Zarrabi A. Esmaeili Y, et al. J Control Release. 2022 May;345:147-175. doi: 10.1016/j.jconrel.2022.03.001. Epub 2022 Mar 3. J Control Release. 2022. PMID: 35248646 Review.
Protein homeostasis is a vital process for cell function and, therefore, disruption of the molecular mechanisms involved in this process, such as autophagy, may contribute to neurodegenerative diseases (NDs). Apart from autophagy disruption, excess oxidative stress …
Protein homeostasis is a vital process for cell function and, therefore, disruption of the molecular mechanisms involved in this process, su …
Nrf2/ARE Pathway as a Therapeutic Target for the Treatment of Parkinson Diseases.
Gureev AP, Popov VN. Gureev AP, et al. Neurochem Res. 2019 Oct;44(10):2273-2279. doi: 10.1007/s11064-018-02711-2. Epub 2019 Jan 7. Neurochem Res. 2019. PMID: 30617864 Review.
It participates in the maintenance of mitochondrial homeostasis, which is provided by an optimal ratio in the processes of mitochondrial biogenesis and mitophagy, as well as the optimal ratio of ROS production and ROS scavenging. ...All this makes Nrf2 an optimal ta …
It participates in the maintenance of mitochondrial homeostasis, which is provided by an optimal ratio in the processes of mitocho …
LIFESTAT - Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction.
Christensen CL, Wulff Helge J, Krasnik A, Kriegbaum M, Rasmussen LJ, Hickson ID, Liisberg KB, Oxlund B, Bruun B, Lau SR, Olsen MN, Andersen JS, Heltberg AS, Kuhlman AB, Morville TH, Dohlmann TL, Larsen S, Dela F. Christensen CL, et al. Scand J Public Health. 2016 Jul;44(5):534-9. doi: 10.1177/1403494816636304. Epub 2016 Mar 3. Scand J Public Health. 2016. PMID: 26939591
The potential benefit of treatment with statins should be considered in light of evidence that statin use has prevalent and unintended side effects (e.g. myalgia, and glucose and exercise intolerance). METHODS: The LIFESTAT project combines invasive human experiments, biom …
The potential benefit of treatment with statins should be considered in light of evidence that statin use has prevalent and unintended side …
Disease- and treatment-related predictors of hepatic mitochondrial dysfunction in chronic HIV infection assessed by non-invasive (13)C-methionine breath test diagnostic.
Banasch M, Knyhala K, Kollar S, Serova K, Potthoff A, Schlottmann R, Schmidt WE, Brockmeyer NH, Goetze O. Banasch M, et al. Eur J Med Res. 2008 Sep 22;13(9):401-8. Eur J Med Res. 2008. PMID: 18948231
The aim was to assess disease- and treatment-related predictors on hepatic mitochondrial dysfunction in HIV infection by means of a new (13)C-methionine breath test (MeBT). PATIENTS AND METHODS: 148 HIV positive individuals with and without antiretroviral treatment (ART) [ …
The aim was to assess disease- and treatment-related predictors on hepatic mitochondrial dysfunction in HIV infection by means of a n …