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Page 1
Sertoli cell-only syndrome: etiology and clinical management.
Ghanami Gashti N, Sadighi Gilani MA, Abbasi M. Ghanami Gashti N, et al. J Assist Reprod Genet. 2021 Mar;38(3):559-572. doi: 10.1007/s10815-021-02063-x. Epub 2021 Jan 11. J Assist Reprod Genet. 2021. PMID: 33428073 Free PMC article. Review.
Almost 50% of infertility cases are due to male factors, and spermatogenesis failure is one of the most severe forms of male infertility. Sertoli cell-only syndrome (SCOS) also known as germ cell aplasia is characterized by azoospermia in which the sem …
Almost 50% of infertility cases are due to male factors, and spermatogenesis failure is one of the most severe forms of male infertility. …
Biotechnological approaches to the treatment of aspermatogenic men.
Aponte PM, Schlatt S, Franca LR. Aponte PM, et al. Clinics (Sao Paulo). 2013;68 Suppl 1(Suppl 1):157-67. doi: 10.6061/clinics/2013(sup01)18. Clinics (Sao Paulo). 2013. PMID: 23503966 Free PMC article. Review.
Sperm derivation in vitro is already feasible in fish and mammals through organ culture or 3D systems, and it is very useful in conditions of germ cell arrest or in type II Sertoli-cell-only syndrome. Patients afflicted by type I Sertoli-cell …
Sperm derivation in vitro is already feasible in fish and mammals through organ culture or 3D systems, and it is very useful in conditions o …
Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility.
Olesen IA, Andersson AM, Aksglaede L, Skakkebaek NE, Rajpert-de Meyts E, Joergensen N, Juul A. Olesen IA, et al. Fertil Steril. 2017 Jan;107(1):74-82.e7. doi: 10.1016/j.fertnstert.2016.09.015. Epub 2016 Oct 25. Fertil Steril. 2017. PMID: 27793385 Free article.
One hundred thirty-three had azoospermia, of which 58 had testicular biopsy findings (Sertoli cell-only syndrome: n = 23; spermatogenic arrest: n = 7; impaired spermatogenesis and atrophy: n = 28). Additionally, in idiopathic infertile men and infertil …
One hundred thirty-three had azoospermia, of which 58 had testicular biopsy findings (Sertoli cell-only syndrome …
Management of carcinoma-in-situ of the testis.
von der Maase H, Giwercman A, Müller J, Skakkebaek NE. von der Maase H, et al. Int J Androl. 1987 Feb;10(1):209-20. doi: 10.1111/j.1365-2605.1987.tb00186.x. Int J Androl. 1987. PMID: 2438219
Eight patients with unilateral testicular cancer and contralateral CIS received localized irradiation (20 Gy in ten fractions of 2 Gy) to the remaining testis: after 3 months the CIS cells had disappeared and 'Sertoli-cell-only' tubules were found. LH and FSH …
Eight patients with unilateral testicular cancer and contralateral CIS received localized irradiation (20 Gy in ten fractions of 2 Gy) to th …
Criteria predicting the absence of spermatozoa in the Sertoli cell-only syndrome can be used to improve success rates of sperm retrieval.
Anniballo R, Ubaldi F, Cobellis L, Sorrentino M, Rienzi L, Greco E, Tesarik J. Anniballo R, et al. Hum Reprod. 2000 Nov;15(11):2269-77. doi: 10.1093/humrep/15.11.2269. Hum Reprod. 2000. PMID: 11056118 Review.
One of the most frequent pathological pictures characterizing complete absence of spermatozoa is germinal aplasia (Sertoli cell- only syndrome or SCOS). Two different histological patterns of SCOS have been already described during the pa …
One of the most frequent pathological pictures characterizing complete absence of spermatozoa is germinal aplasia (Sertoli …
Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma.
Drabovich AP, Dimitromanolakis A, Saraon P, Soosaipillai A, Batruch I, Mullen B, Jarvi K, Diamandis EP. Drabovich AP, et al. Sci Transl Med. 2013 Nov 20;5(212):212ra160. doi: 10.1126/scitranslmed.3006260. Sci Transl Med. 2013. PMID: 24259048
Testicular biopsy is the only definitive diagnostic method to distinguish between obstructive (OA) and nonobstructive (NOA) azoospermia and to identify the NOA subtypes of hypospermatogenesis, maturation arrest and Sertoli cell-only syndrome. We measur …
Testicular biopsy is the only definitive diagnostic method to distinguish between obstructive (OA) and nonobstructive (NOA) azoospermia and …
Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility.
Korbakis D, Schiza C, Brinc D, Soosaipillai A, Karakosta TD, Légaré C, Sullivan R, Mullen B, Jarvi K, Diamandis EP, Drabovich AP. Korbakis D, et al. BMC Med. 2017 Mar 23;15(1):60. doi: 10.1186/s12916-017-0817-5. BMC Med. 2017. PMID: 28330469 Free PMC article.
TEX101 median values were estimated in healthy, fertile pre-vasectomy men (5436 ng/mL, N = 64) and in patients with unexplained infertility (4967 ng/mL, N = 277), oligospermia (450 ng/mL, N = 270), and azoospermia (0.5 ng/mL, N = 137). Fertile post-vasectomy men (N = 57) and pati …
TEX101 median values were estimated in healthy, fertile pre-vasectomy men (5436 ng/mL, N = 64) and in patients with unexplained infertility …
Testes in infants with Prader-Willi syndrome: human chorionic gonadotropin treatment, surgery and histology.
Bakker NE, Wolffenbuttel KP, Looijenga LH, Hokken-Koelega AC. Bakker NE, et al. J Urol. 2015 Jan;193(1):291-8. doi: 10.1016/j.juro.2014.07.113. Epub 2014 Aug 7. J Urol. 2015. PMID: 25109686
PURPOSE: Boys with Prader-Willi syndrome often have undescended testes. Prospective studies on the treatment of cryptorchidism in these patients are lacking. ...In addition, 4 boys had Sertoli cell only syndrome and 1 had a vanished testi …
PURPOSE: Boys with Prader-Willi syndrome often have undescended testes. Prospective studies on the treatment of cryptorchidism …
Testis ultrasound in Klinefelter syndrome infertile men: making the diagnosis and avoiding inappropriate management.
Rocher L, Moya L, Correas JM, Mutuon P, Ferlicot S, Young J, Izard V, Benoit G, Brailly-Tabard S, Bellin MF. Rocher L, et al. Abdom Radiol (NY). 2016 Aug;41(8):1596-603. doi: 10.1007/s00261-016-0713-z. Abdom Radiol (NY). 2016. PMID: 27029388
OBJECTIVE: To compare the testicular Color Doppler ultrasound (US), hormone levels, and histological results from 67 infertile men with Klinefelter syndrome (KS), vs. 66 non-KS non-obstructive azoospermic men. METHODS: Scrotal US images were collected from 67 infertile KS …
OBJECTIVE: To compare the testicular Color Doppler ultrasound (US), hormone levels, and histological results from 67 infertile men with Klin …
12 results