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Page 1
Eosinophilic Dermatoses: Recognition and Management.
Marzano AV, Genovese G. Marzano AV, et al. Am J Clin Dermatol. 2020 Aug;21(4):525-539. doi: 10.1007/s40257-020-00520-4. Am J Clin Dermatol. 2020. PMID: 32394361 Review.
Eosinophilic dermatoses encompass a broad spectrum of diseases of different etiologies hallmarked by eosinophilic infiltration of the skin and/or mucous membranes, with or without associated blood eosinophilia. ...We review clinicopathologic features and mana …
Eosinophilic dermatoses encompass a broad spectrum of diseases of different etiologies hallmarked by eosinophilic infiltrat …
Clinical features, diagnosis and management of cephalosporin-induced acute generalized exanthematous pustulosis.
Lei H, Deng H, Liu X, Li Z, Wang C. Lei H, et al. J Clin Pharm Ther. 2022 Dec;47(12):2008-2013. doi: 10.1111/jcpt.13738. Epub 2022 Jul 31. J Clin Pharm Ther. 2022. PMID: 35909299
Histology of AGEP showed subcorneal pustules (56.3%), intraepidermal cavernous pustules (37.5%), with papillary dermal edema (37.5%), containing neutrophils and eosinophilic infiltration (71.9%). ...
Histology of AGEP showed subcorneal pustules (56.3%), intraepidermal cavernous pustules (37.5%), with papillary dermal edema (37.5%), …
Clinical characterization, treatment, and outcome of nivolumab-induced bullous pemphigoid.
Liu M, Yuan M, Sun W, Li Z, Zhou X, Wang C. Liu M, et al. Invest New Drugs. 2023 Dec;41(6):802-807. doi: 10.1007/s10637-023-01397-w. Epub 2023 Sep 29. Invest New Drugs. 2023. PMID: 37773473
Skin biopsies mainly showed subepidermal bullous/blister (50.0%) and eosinophilic infiltration (46.7%). Direct immunofluorescence showed mainly linear deposition of C3 and IgG (46.7%) at the dermal-epidermal junction. ...
Skin biopsies mainly showed subepidermal bullous/blister (50.0%) and eosinophilic infiltration (46.7%). Direct immunofluoresce …
Association of Peripheral Blood and Cutaneous Eosinophils With Bullous Pemphigoid Disease Severity and Treatment Outcomes.
Garrido PM, Aguado-Lobo M, Espinosa-Lara P, Soares-Almeida L, Filipe P. Garrido PM, et al. Actas Dermosifiliogr. 2022 Oct;113(9):881-887. doi: 10.1016/j.ad.2022.05.021. Epub 2022 Jun 2. Actas Dermosifiliogr. 2022. PMID: 35659610 Free article. English, Spanish.
Nevertheless, the impact of circulating and dermal infiltrate eosinophil levels on BP remains poorly understood. The main objective of this work was to investigate the association of peripheral blood and dermal infiltrate eosinophil level …
Nevertheless, the impact of circulating and dermal infiltrate eosinophil levels on BP remains poorly understood. The ma …
Skin Eosinophil Counts in Bullous Pemphigoid as a Prognostic Factor for Disease Severity and Treatment Response.
Baum S, Engler Markowitz M, Lyakhovitsky A, Gershon R, Aviv H, Segal Z, Barzilai A. Baum S, et al. Acta Derm Venereol. 2023 Jan 10;103:adv00850. doi: 10.2340/actadv.v102.2938. Acta Derm Venereol. 2023. PMID: 36250732 Free PMC article.
Dermal infiltration of eosinophils and eosinophilic spongiosis are prominent features of bullous pemphigoid lesions. ...At all follow-up points patients with no tissue eosinophils had a better response to treatment than patients with any tissue …
Dermal infiltration of eosinophils and eosinophilic spongiosis are prominent features of bullous pemphigoid lesi …
Reduced dermal infiltration of cytokine-expressing inflammatory cells in atopic dermatitis after short-term topical tacrolimus treatment.
Simon D, Vassina E, Yousefi S, Kozlowski E, Braathen LR, Simon HU. Simon D, et al. J Allergy Clin Immunol. 2004 Oct;114(4):887-95. doi: 10.1016/j.jaci.2004.05.066. J Allergy Clin Immunol. 2004. PMID: 15480330
They target signaling pathways that control gene expression, particularly the expression of cytokines. OBJECTIVE: We examined the cellular infiltrate in skin lesions of 10 patients with AD and characterized the cytokine pattern expressed by the infiltrating cells be …
They target signaling pathways that control gene expression, particularly the expression of cytokines. OBJECTIVE: We examined the cellular …
Association of transient dermal mastocytosis and elevated plasma tryptase levels with development of adverse reactions after treatment of onchocerciasis with ivermectin.
Cooper PJ, Schwartz LB, Irani AM, Awadzi K, Guderian RH, Nutman TB. Cooper PJ, et al. J Infect Dis. 2002 Nov 1;186(9):1307-13. doi: 10.1086/344318. Epub 2002 Oct 11. J Infect Dis. 2002. PMID: 12402200
After treatment, an increase in tryptase levels was observed concurrent with the onset of blood eosinopenia and preceding the appearance of plasma eosinophil-derived neurotoxin (EDN) and interleukin-5. Tryptase levels were correlated with development of peripheral eosinope …
After treatment, an increase in tryptase levels was observed concurrent with the onset of blood eosinopenia and preceding the appearance of …
Grover disease: a reappraisal of histopathological diagnostic criteria in 120 cases.
Fernández-Figueras MT, Puig L, Cannata P, Cuatrecases M, Quer A, Ferrándiz C, Ariza A. Fernández-Figueras MT, et al. Am J Dermatopathol. 2010 Aug;32(6):541-9. doi: 10.1097/DAD.0b013e3181c80cf9. Am J Dermatopathol. 2010. PMID: 20526170
Specifically, in addition to the commonly described GD findings, we have detected cases with porokeratosis-like oblique columns of parakeratosis, lesions showing a nevoid or lentiginous silhouette, intraepidermal vesicular lesions, lichenoid changes with basal vacuolization and d …
Specifically, in addition to the commonly described GD findings, we have detected cases with porokeratosis-like oblique columns of parakerat …
Lymphomatoid papulosis in children: experience of five cases and the treatment efficacy of methotrexate.
Yip L, Darling S, Orchard D. Yip L, et al. Australas J Dermatol. 2011 Nov;52(4):279-83. doi: 10.1111/j.1440-0960.2010.00734.x. Epub 2011 Mar 1. Australas J Dermatol. 2011. PMID: 22070703
Clinically and histologically, the features of LyP in children can mimic insect bite reactions, with prominent dermal neutrophils and eosinophils. However, CD30 immunohistochemical staining of atypical lymphocytes within a mixed inflammatory infiltrate should …
Clinically and histologically, the features of LyP in children can mimic insect bite reactions, with prominent dermal neutrophils and …
Eotaxin and RANTES expression by the dermal endothelium is associated with eosinophil infiltration after ivermectin treatment of onchocerciasis.
Cooper PJ, Beck LA, Espinel I, Deyampert NM, Hartnell A, Jose PJ, Paredes W, Guderian RH, Nutman TB. Cooper PJ, et al. Clin Immunol. 2000 Apr;95(1 Pt 1):51-61. doi: 10.1006/clim.1999.4829. Clin Immunol. 2000. PMID: 10794432
Adverse reactions in infected subjects were associated with the appearance of eosinophils in the dermis as part of a perivascular inflammatory infiltrate. ...While RANTES expression was transient, eotaxin expression increased in parallel with increasing eosinophi …
Adverse reactions in infected subjects were associated with the appearance of eosinophils in the dermis as part of a perivascular inf …