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Diagnosis and management of neonatal leukaemia.
van der Linden MH, Creemers S, Pieters R. van der Linden MH, et al. Semin Fetal Neonatal Med. 2012 Aug;17(4):192-195. doi: 10.1016/j.siny.2012.03.003. Epub 2012 Apr 15. Semin Fetal Neonatal Med. 2012. PMID: 22510298 Review.
Leukaemia in neonates (infants <1 month) is rare, whereby neonatal acute myeloid leukaemia (AML) is more frequent than neonatal acute lymphoblastic leukaemia (ALL). ...Treatment includes intensive multi-agent chemotherapy, usually with age-related dose adj …
Leukaemia in neonates (infants <1 month) is rare, whereby neonatal acute myeloid leukaemia (AML) is more frequent than neon …
International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.
Hrusak O, de Haas V, Stancikova J, Vakrmanova B, Janotova I, Mejstrikova E, Capek V, Trka J, Zaliova M, Luks A, Bleckmann K, Möricke A, Irving J, Konatkowska B, Alexander TB, Inaba H, Schmiegelow K, Stokley S, Zemanova Z, Moorman AV, Rossi JG, Felice MS, Dalla-Pozza L, Morales J, Dworzak M, Buldini B, Basso G, Campbell M, Cabrera ME, Marinov N, Elitzur S, Izraeli S, Luria D, Feuerstein T, Kolenova A, Svec P, Kreminska O, Rabin KR, Polychronopoulou S, da Costa E, Marquart HV, Kattamis A, Ratei R, Reinhardt D, Choi JK, Schrappe M, Stary J. Hrusak O, et al. Blood. 2018 Jul 19;132(3):264-276. doi: 10.1182/blood-2017-12-821363. Epub 2018 May 2. Blood. 2018. PMID: 29720486 Free article.
Despite attempts to improve the definitions of ambiguous lineage leukemia (ALAL) during the last 2 decades, general therapy recommendations are missing. ...Survival statistics were used to compare the prognosis of subsets and types of treatment. Five-year event-free …
Despite attempts to improve the definitions of ambiguous lineage leukemia (ALAL) during the last 2 decades, general therapy re …
Acute lymphoblastic leukemia-like treatment regimen provides better response in mixed phenotype acute leukemia: a comparative study between adults and pediatric MPAL patients.
Rasekh EO, Osman R, Ibraheem D, Madney Y, Radwan E, Gameel A, Abdelhafiz A, Kamel A, Elfishawi S. Rasekh EO, et al. Ann Hematol. 2021 Mar;100(3):699-707. doi: 10.1007/s00277-020-04354-2. Epub 2020 Nov 23. Ann Hematol. 2021. PMID: 33230570
Mixed phenotype acute leukemia (MPAL) is a rare type of leukemia with a limited number of studies conducted to characterize its clinical spectrum and most importantly the best treatment modality. ...The incidence of MPAL was 4% of acute leukemia …
Mixed phenotype acute leukemia (MPAL) is a rare type of leukemia with a limited number of studies conducted to characte …
Stem cell transplant in the treatment of childhood biphenotypic acute leukemia.
Park JA, Ghim TT, Bae Kw, Im HJ, Jang SS, Park CJ, Chi HS, Seo JJ. Park JA, et al. Pediatr Blood Cancer. 2009 Sep;53(3):444-52. doi: 10.1002/pbc.22105. Pediatr Blood Cancer. 2009. PMID: 19489056
BACKGROUND: Many studies have found that biphenotypic acute leukemia (BAL) is associated with a poor outcome. METHODS: We retrospectively reviewed the medical records and analyzed clinicopathological data on 25 children with BAL, and correlated outcomes with …
BACKGROUND: Many studies have found that biphenotypic acute leukemia (BAL) is associated with a poor outcome. METHODS: …
Mixed phenotype acute leukemia: A study of 61 cases using World Health Organization and European Group for the Immunological Classification of Leukaemias criteria.
Weinberg OK, Seetharam M, Ren L, Alizadeh A, Arber DA. Weinberg OK, et al. Am J Clin Pathol. 2014 Dec;142(6):803-8. doi: 10.1309/AJCPPVUPOTUVOIB5. Am J Clin Pathol. 2014. PMID: 25389334
OBJECTIVES: The 2008 World Health Organization (WHO) classification system grouped bilineal and biphenotypic acute leukemias together under a new heading of mixed phenotype acute leukemia (MPAL). ...METHODS: Sixty-one patients diagnosed with MPAL using …
OBJECTIVES: The 2008 World Health Organization (WHO) classification system grouped bilineal and biphenotypic acute leukemias t …
Clinical features and treatment outcome of children with biphenotypic CD2+ CD19+ acute lymphoblastic leukemia: a Children's Cancer Group study.
Uckun FM, Gaynon P, Sather H, Arthur D, Trigg M, Tubergen D, Nachman J, Steinherz P, Sensel MG, Reaman GR. Uckun FM, et al. Blood. 1997 Apr 1;89(7):2488-93. Blood. 1997. PMID: 9116293 Free article.
Leukemic cells from a subset of children with acute lymphoblastic leukemia (ALL) express lymphoid antigens of both T lineage and B lineage, but the clinical significance of this immunophenotype is unknown. ...Thus, pediatric ALL patients treated on contemporary CCG …
Leukemic cells from a subset of children with acute lymphoblastic leukemia (ALL) express lymphoid antigens of both T lineage a …
Methylenetetrahydrofolate reductase A1298C genotypes are associated with the risks of acute lymphoblastic leukaemia and chronic myelogenous leukaemia in the Korean population.
Hur M, Park JY, Cho HC, Lee KM, Shin HY, Cho HI. Hur M, et al. Clin Lab Haematol. 2006 Jun;28(3):154-9. doi: 10.1111/j.1365-2257.2006.00769.x. Clin Lab Haematol. 2006. PMID: 16706930
We investigated the association between MTHFR polymorphisms and the risks of acute and chronic leukaemias. MTHFR C677T and A1298C were genotyped in 396 Korean individuals using multiplex polymerase chain reaction/restriction fragment-length polymorphism. They were acute …
We investigated the association between MTHFR polymorphisms and the risks of acute and chronic leukaemias. MTHFR C677T and A1298C wer …