Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1911 1
1913 1
1924 1
1932 2
1935 1
1940 3
1942 1
1943 3
1945 2
1946 3
1947 6
1948 7
1949 3
1950 3
1951 9
1952 6
1953 9
1954 10
1955 10
1956 9
1957 9
1958 15
1959 13
1960 22
1961 16
1962 26
1963 78
1964 130
1965 115
1966 124
1967 138
1968 160
1969 184
1970 177
1971 206
1972 203
1973 199
1974 199
1975 292
1976 246
1977 248
1978 217
1979 244
1980 289
1981 261
1982 265
1983 302
1984 333
1985 323
1986 371
1987 419
1988 401
1989 416
1990 444
1991 426
1992 478
1993 455
1994 482
1995 483
1996 422
1997 454
1998 441
1999 481
2000 527
2001 483
2002 481
2003 506
2004 472
2005 513
2006 476
2007 529
2008 587
2009 573
2010 578
2011 679
2012 730
2013 777
2014 788
2015 810
2016 807
2017 853
2018 884
2019 951
2020 1085
2021 1143
2022 1214
2023 1206
2024 542

Text availability

Article attribute

Article type

Publication date

Search Results

27,342 results

Results by year

Filters applied: . Clear all
Page 1
Linoleic acid potentiates CD8(+) T cell metabolic fitness and antitumor immunity.
Nava Lauson CB, Tiberti S, Corsetto PA, Conte F, Tyagi P, Machwirth M, Ebert S, Loffreda A, Scheller L, Sheta D, Mokhtari Z, Peters T, Raman AT, Greco F, Rizzo AM, Beilhack A, Signore G, Tumino N, Vacca P, McDonnell LA, Raimondi A, Greenberg PD, Huppa JB, Cardaci S, Caruana I, Rodighiero S, Nezi L, Manzo T. Nava Lauson CB, et al. Cell Metab. 2023 Apr 4;35(4):633-650.e9. doi: 10.1016/j.cmet.2023.02.013. Epub 2023 Mar 9. Cell Metab. 2023. PMID: 36898381 Free article.
However, the extent to which lipids can affect the CTL functions and fate remains unexplored. Here, we show that linoleic acid (LA) is a major positive regulator of CTL activity by improving metabolic fitness, preventing exhaustion, and stimulating a memory-like phe …
However, the extent to which lipids can affect the CTL functions and fate remains unexplored. Here, we show that linoleic acid …
Linoleic acid.
Whelan J, Fritsche K. Whelan J, et al. Adv Nutr. 2013 May 1;4(3):311-2. doi: 10.3945/an.113.003772. Adv Nutr. 2013. PMID: 23674797 Free PMC article. Review. No abstract available.
Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation.
Abe I, Oguri Y, Verkerke ARP, Monteiro LB, Knuth CM, Auger C, Qiu Y, Westcott GP, Cinti S, Shinoda K, Jeschke MG, Kajimura S. Abe I, et al. Dev Cell. 2022 Dec 5;57(23):2623-2637.e8. doi: 10.1016/j.devcel.2022.11.007. Dev Cell. 2022. PMID: 36473459 Free PMC article.
A subset of adipocyte progenitors, as marked by cell surface markers PDGFRalpha or Sca1 and CD81, harbored cristae-rich mitochondria and actively imported linoleic acid via a fatty acid transporter CD36. Linoleic acid not only was oxidized as fu …
A subset of adipocyte progenitors, as marked by cell surface markers PDGFRalpha or Sca1 and CD81, harbored cristae-rich mitochondria and act …
The Role of Arachidonic and Linoleic Acid Derivatives in Pathological Pregnancies and the Human Reproduction Process.
Szczuko M, Kikut J, Komorniak N, Bilicki J, Celewicz Z, Ziętek M. Szczuko M, et al. Int J Mol Sci. 2020 Dec 17;21(24):9628. doi: 10.3390/ijms21249628. Int J Mol Sci. 2020. PMID: 33348841 Free PMC article. Review.
The aim of the available literature review was to focus on the role of the proinflammatory mediators of AA and LA derivatives in pathological conditions related to reproduction and pregnancy. Arachidonic (AA) and linoleic acid (LA) derivatives play important roles i …
The aim of the available literature review was to focus on the role of the proinflammatory mediators of AA and LA derivatives in pathologica …
Linoleic acid: between doubts and certainties.
Choque B, Catheline D, Rioux V, Legrand P. Choque B, et al. Biochimie. 2014 Jan;96:14-21. doi: 10.1016/j.biochi.2013.07.012. Epub 2013 Jul 27. Biochimie. 2014. PMID: 23900039 Review.
Linoleic acid is the most abundant polyunsaturated fatty acid in human nutrition and represents about 14 g per day in the US diet. ...Linoleic acid is a direct precursor of the bioactive oxidized linoleic acid metabolites. ...
Linoleic acid is the most abundant polyunsaturated fatty acid in human nutrition and represents about 14 g per day in t …
Linoleic acid and the pathogenesis of obesity.
Naughton SS, Mathai ML, Hryciw DH, McAinch AJ. Naughton SS, et al. Prostaglandins Other Lipid Mediat. 2016 Sep;125:90-9. doi: 10.1016/j.prostaglandins.2016.06.003. Epub 2016 Jun 24. Prostaglandins Other Lipid Mediat. 2016. PMID: 27350414 Review.
These nutrition transitions are typified by an increased intake of high linoleic acid (LA) plant oils, due to their abundance and low price, resulting in an increase in the PUFA n-6:n-3 ratio. This increase in LA above what is estimated to be required is hypothesise …
These nutrition transitions are typified by an increased intake of high linoleic acid (LA) plant oils, due to their abundance …
Feeding mice a diet high in oxidized linoleic acid metabolites does not alter liver oxylipin concentrations.
Liang N, Hennebelle M, Gaul S, Johnson CD, Zhang Z, Kirpich IA, McClain CJ, Feldstein AE, Ramsden CE, Taha AY. Liang N, et al. Prostaglandins Leukot Essent Fatty Acids. 2021 Sep;172:102316. doi: 10.1016/j.plefa.2021.102316. Epub 2021 Jun 24. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 34403987 Free PMC article.
The oxidation of dietary linoleic acid (LA) produces oxidized LA metabolites (OXLAMs) known to regulate multiple signaling pathways in vivo. ...
The oxidation of dietary linoleic acid (LA) produces oxidized LA metabolites (OXLAMs) known to regulate multiple signaling pat …
Linoleic acid and the regulation of glucose homeostasis: A review of the evidence.
Hamilton JS, Klett EL. Hamilton JS, et al. Prostaglandins Leukot Essent Fatty Acids. 2021 Dec;175:102366. doi: 10.1016/j.plefa.2021.102366. Epub 2021 Oct 29. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 34763302 Free PMC article. Review.
The consumption of linoleic acid (LA, omega-6 18:2), the most common omega-6 polyunsaturated fatty acid (PUFA) in the Modern Western diet (MWD), has significantly increased over the last century in tandem with unprecedented incidence of chronic metabolic dise …
The consumption of linoleic acid (LA, omega-6 18:2), the most common omega-6 polyunsaturated fatty acid (PUFA) in the M …
The health implications of changing linoleic acid intakes.
Whelan J. Whelan J. Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):165-7. doi: 10.1016/j.plefa.2008.09.013. Epub 2008 Nov 5. Prostaglandins Leukot Essent Fatty Acids. 2008. PMID: 18990554 Review.
Linoleic acid is the most prominent polyunsaturated fatty acid (PUFA) in the Western diet. ...The following series of papers examines the impact of modifying dietary levels of linoleic acid on health outcomes. The authors were asked to start wit …
Linoleic acid is the most prominent polyunsaturated fatty acid (PUFA) in the Western diet. ...The following series of p …
CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid.
Zhang J, Yang J, Duval C, Edin ML, Williams A, Lei L, Tu M, Pourmand E, Song R, Graves JP, DeGraff LM, Wong JJ, Wang Y, Sun Q, Sanidad KZ, Wong S, Han Y, Zhang Z, Lee KSS, Park Y, Xiao H, Liu Z, Decker EA, Cui W, Zeldin DC, Zhang G. Zhang J, et al. FASEB J. 2023 Jul;37(7):e23009. doi: 10.1096/fj.202300786R. FASEB J. 2023. PMID: 37273180
Human and animal studies support that consuming a high level of linoleic acid (LA, 18:2omega-6), an essential fatty acid and key component of the human diet, increases the risk of colon cancer. ...Overall, these results support that CYP monooxygenase-mediated …
Human and animal studies support that consuming a high level of linoleic acid (LA, 18:2omega-6), an essential fatty acid …
27,342 results
You have reached the last available page of results. Please see the User Guide for more information.