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44 results

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Page 1
DICER1-associated Tumors in the Female Genital Tract: Molecular Basis, Clinicopathologic Features, and Differential Diagnosis.
Han LM, Weiel JJ, Longacre TA, Folkins AK. Han LM, et al. Adv Anat Pathol. 2022 Sep 1;29(5):297-308. doi: 10.1097/PAP.0000000000000351. Epub 2022 Jul 1. Adv Anat Pathol. 2022. PMID: 35778792 Review.
Within the gynecologic tract, germline mutations in DICER1 are associated with an array of rare tumors, including Sertoli-Leydig cell tumor, embryonal rhabdomyosarcoma of the cervix, gynandroblastoma, and juvenile granulosa cell tumor, which typ …
Within the gynecologic tract, germline mutations in DICER1 are associated with an array of rare tumors, including Sertoli-Leydig c
Peutz-Jeghers Syndrome: Pathobiology, Pathologic Manifestations, and Suggestions for Recommending Genetic Testing in Pathology Reports.
Meserve EE, Nucci MR. Meserve EE, et al. Surg Pathol Clin. 2016 Jun;9(2):243-68. doi: 10.1016/j.path.2016.01.006. Surg Pathol Clin. 2016. PMID: 27241107 Review.
Peutz-Jeghers syndrome (PJS), in most cases, is attributed to mutation in STK11/LKB1 and is clinically characterized by gastrointestinal hamartomatous polyposis, mucocutaneous pigmentation, and predisposition to certain neoplasms. There are currently no recommended gynecol …
Peutz-Jeghers syndrome (PJS), in most cases, is attributed to mutation in STK11/LKB1 and is clinically characterized by gastrointestinal ham …
From diagnosis to treatment of androgen-secreting ovarian tumors: a practical approach.
Rojewska P, Meczekalski B, Bala G, Luisi S, Podfigurna A. Rojewska P, et al. Gynecol Endocrinol. 2022 Jul;38(7):537-542. doi: 10.1080/09513590.2022.2083104. Epub 2022 Jun 1. Gynecol Endocrinol. 2022. PMID: 35647677
Only 1% of ovarian tumors will secrete androgens causing clinical hyperandrogenism. Most androgen-secreting neoplasms (ASN) derive from sex cord or stroma cells of the ovary and may affect both premenopausal and postmenopausal women. Typically, a patient will present repor …
Only 1% of ovarian tumors will secrete androgens causing clinical hyperandrogenism. Most androgen-secreting neoplasms (ASN) derive fr …
Difficult differential diagnoses in testicular pathology.
Ye H, Ulbright TM. Ye H, et al. Arch Pathol Lab Med. 2012 Apr;136(4):435-46. doi: 10.5858/arpa.2011-0475-RA. Arch Pathol Lab Med. 2012. PMID: 22458906 Free article. Review.
CONTEXT: Although relatively rare, testicular cancer is the most common solid organ malignancy in young men and remains a leading cause of cancer death in this population. ...CONCLUSIONS: Problematic differential diagnoses include seminoma versus nonseminomatous germ ce
CONTEXT: Although relatively rare, testicular cancer is the most common solid organ malignancy in young men and remains a leading cau …
Embryonal Rhabdomyosarcoma of the Uterine Cervix: A Clinicopathologic Study of 94 Cases Emphasizing Issues in Differential Diagnosis Staging, and Prognostic Factors.
Devins KM, Young RH, Ghioni M, Burandt E, Bennett JA, Oliva E. Devins KM, et al. Am J Surg Pathol. 2022 Nov 1;46(11):1477-1489. doi: 10.1097/PAS.0000000000001933. Epub 2022 Aug 9. Am J Surg Pathol. 2022. PMID: 35941719
We report 94 tumors that arose in patients aged 7 to 59 (median=23) years and presented with vaginal bleeding (52), protruding vaginal mass (17), cervical polyp (8), or expelled tumor fragments per vagina (5). Nine had DICER1 syndrome, 8 of whom had other syndromic manifes …
We report 94 tumors that arose in patients aged 7 to 59 (median=23) years and presented with vaginal bleeding (52), protruding vaginal mass …
Treatment and survival of patients with malignant ovarian sex cord-stromal cell tumours: An analysis of the Arbeitsgemeinschaft fur Gynakologische Onkologie (AGO) study group CORSETT database.
Klar M, Plett H, Harter P, Heitz F, Kommoss S, Hartkopf AD, Grube M, Roser E, Sehouli J, Braicu I, Czogalla B, Burges A, Bossart M, Hasanov MF, Link T, Staebler A, Mayr D, Buderath P, Hasenburg A. Klar M, et al. J Surg Oncol. 2023 Jul;128(1):111-118. doi: 10.1002/jso.27248. Epub 2023 Mar 28. J Surg Oncol. 2023. PMID: 36975108 Review.
BACKGROUND: Malignant sex cord-stromal cell tumours (SCST) account for only 7% of ovarian malignancies. ...RESULTS: Two hundred and sixty-two SCST patients were included. One hundred and ninety-one Granulosa-cell tumour (GCT) and 17 Sertoli-Leyd …
BACKGROUND: Malignant sex cord-stromal cell tumours (SCST) account for only 7% of ovarian malignancies. ...RESULTS: Two …
CT and MR imaging of ovarian tumors with emphasis on differential diagnosis.
Jung SE, Lee JM, Rha SE, Byun JY, Jung JI, Hahn ST. Jung SE, et al. Radiographics. 2002 Nov-Dec;22(6):1305-25. doi: 10.1148/rg.226025033. Radiographics. 2002. PMID: 12432104 Review.
Ovarian tumors are classified on the basis of tumor origin as epithelial tumors (serous and mucinous tumors, endometrioid and clear cell carcinomas, Brenner tumor), germ cell tumors (mature and immature teratomas, dysgerminoma, endodermal sinus tumo
Ovarian tumors are classified on the basis of tumor origin as epithelial tumors (serous and mucinous tumors, endometrioid and clear …
Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation.
Stratakis CA, Kirschner LS, Carney JA. Stratakis CA, et al. J Clin Endocrinol Metab. 2001 Sep;86(9):4041-6. doi: 10.1210/jcem.86.9.7903. J Clin Endocrinol Metab. 2001. PMID: 11549623 Review.
Carney complex shares skin abnormalities and some nonendocrine tumors with the lentiginoses and certain of the hamartomatoses, particularly Peutz-Jeghers syndrome, with which it shares mucosal lentiginosis and an unusual gonadal tumor, large-cell calcifying Serto
Carney complex shares skin abnormalities and some nonendocrine tumors with the lentiginoses and certain of the hamartomatoses, particularly …
Management of early ovarian cancer: germ cell and sex cord-stromal tumors.
Gershenson DM. Gershenson DM. Gynecol Oncol. 1994 Dec;55(3 Pt 2):S62-72. Gynecol Oncol. 1994. PMID: 7530680 Review.
Malignant ovarian germ cell tumors (OGCT) and sex cord-stromal tumors (OSCST), each of which account for less than 5% of all ovarian malignancies, are much less common than epithelial ovarian cancer. ...For patients with metastatic dysgerminoma, chemotherapy,
Malignant ovarian germ cell tumors (OGCT) and sex cord-stromal tumors (OSCST), each of which account for less than 5% of all o
Genetic engineering to study testicular tumorigenesis.
Yan W, Burns KH, Matzuk MM. Yan W, et al. APMIS. 2003 Jan;111(1):174-81; discussion 182-3. doi: 10.1034/j.1600-0463.2003.1110121.x. APMIS. 2003. PMID: 12760377 Review.
In humans, Sertoli cell tumors account for approximately 4% of all testicular tumors, and 20% of these are malignant. ...It had been suggested that endocrine factors play roles in Sertoli cell tumorigenesis by altering cell cycle machiner …
In humans, Sertoli cell tumors account for approximately 4% of all testicular tumors, and 20% of these are malignant. . …
44 results