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Spatholobi Caulis dispensing granule reduces deep vein thrombus burden through antiinflammation via SIRT1 and Nrf2.
Tang P, Liu H, Lin B, Yang W, Chen W, Lu Z, Li P, Gui S, Zhan Y, Lin B. Tang P, et al. Phytomedicine. 2020 Oct;77:153285. doi: 10.1016/j.phymed.2020.153285. Epub 2020 Jul 15. Phytomedicine. 2020. PMID: 32707369
Protein expressions in thrombosed IVCs and/or OGD-stimulated EA. hy926 cells were evaluated by western blot and/or immunofluorescence analyses. RESULTS: SCDG dramatically decreased thrombus weight. SCDG decreased tissue factor (TF) protein expression, inflammatory cells in …
Protein expressions in thrombosed IVCs and/or OGD-stimulated EA. hy926 cells were evaluated by western blot and/or immunofluorescence analys …
Suppression of endothelial t-PA expression by prolonged high laminar shear stress.
Ulfhammer E, Carlström M, Bergh N, Larsson P, Karlsson L, Jern S. Ulfhammer E, et al. Biochem Biophys Res Commun. 2009 Feb 6;379(2):532-6. doi: 10.1016/j.bbrc.2008.12.105. Epub 2008 Dec 29. Biochem Biophys Res Commun. 2009. PMID: 19116134
Primary hypertension is associated with an impaired capacity for acute release of endothelial tissue-type plasminogen activator (t-PA), which is an important local protective response to prevent thrombus extension. As hypertensive vascular remodeling potentially results in …
Primary hypertension is associated with an impaired capacity for acute release of endothelial tissue-type plasminogen activator (t-PA), whic …