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2020 2
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High-Sensitivity Troponin T Testing for Pediatric Patients in the Emergency Department.
Wang AP, Homme JL, Qureshi MY, Sandoval Y, Jaffe AS. Wang AP, et al. Pediatr Cardiol. 2022 Feb;43(2):350-359. doi: 10.1007/s00246-021-02726-7. Epub 2021 Nov 17. Pediatr Cardiol. 2022. PMID: 34787696

Serial hs-cTnT from 106 patients with an initial hs-cTnT < 99th percentile was subsequently elevated in 5 (4.6%); none of whom had a final clinical cardiac diagnosis. Hs-cTnT has high specificity, but low sensitivity when used as a screening tool for myocardial injury w

Serial hs-cTnT from 106 patients with an initial hs-cTnT < 99th percentile was subsequently elevated in 5 (4.6%); none of whom had a fina

Circulating high-sensitivity troponin T and microRNAs as markers of myocardial damage during childhood leukaemia treatment.
Cheung YF, Li VW, Lai CT, Shin VY, Keung W, Cheuk DK, Kwong A, Li RA, Chan GC. Cheung YF, et al. Pediatr Res. 2021 Apr;89(5):1245-1252. doi: 10.1038/s41390-020-1049-5. Epub 2020 Jul 7. Pediatr Res. 2021. PMID: 32634817

Log-transformed hs-cTnT correlated negatively with LV global systolic longitudinal strain (r = -0.38, p < 0.001). Receiver operating characteristic analysis revealed that area under the curve for changes in plasma hs-cTnT from baseline and plasma miR-1 lev

Log-transformed hs-cTnT correlated negatively with LV global systolic longitudinal strain (r = -0.38, p < 0.001). Receiver oper

Normative Values of High-Sensitivity Cardiac Troponin T and N-Terminal pro-B-Type Natriuretic Peptide in Children and Adolescents: A Study from the CALIPER Cohort.
Lam E, Higgins V, Zhang L, Chan MK, Bohn MK, Trajcevski K, Liu P, Adeli K, Nathan PC. Lam E, et al. J Appl Lab Med. 2021 Mar 1;6(2):344-353. doi: 10.1093/jalm/jfaa090. J Appl Lab Med. 2021. PMID: 32995884
Pediatric reference intervals and cut-offs have not been established for Roche's Elecsys Troponin T hs (high sensitive) assay. Although pediatric reference intervals exist for NT-proBNP, cut-off values do not exist. In this study, we report reference intervals and 9 …
Pediatric reference intervals and cut-offs have not been established for Roche's Elecsys Troponin T hs (high sensitive) assay. Although pedi …
Risk Factors for Cardiac Adverse Events in Infants and Children with Complex Heart Disease Scheduled for Bi-ventricular Repair: Prognostic Value of Pre-operative B-Type Natriuretic Peptide and High-Sensitivity Troponin T.
Mori Y, Nakashima Y, Kaneko S, Inoue N, Murakami T. Mori Y, et al. Pediatr Cardiol. 2020 Dec;41(8):1756-1765. doi: 10.1007/s00246-020-02437-5. Epub 2020 Aug 17. Pediatr Cardiol. 2020. PMID: 32808054
Among hemodynamic and laboratory variables, preoperative BNP (OR 14.04; 95% CI 2.15-91.7; p = 0.001) and hs-TnT levels (OR 16.66; 95% CI 2.27-122; p = 0.002) were found to be independent risk factors. Receiver operating characteristic analysis determined BNP …
Among hemodynamic and laboratory variables, preoperative BNP (OR 14.04; 95% CI 2.15-91.7; p = 0.001) and hs-TnT levels (OR 16.66; 95% CI 2.2 …