Novel histotypes of sporadic Creutzfeldt-Jakob disease linked to 129MV genotype.
Cracco L, Puoti G, Cornacchia A, Glisic K, Lee SK, Wang Z, Cohen ML, Appleby BS, Cali I.
Cracco L, et al.
Acta Neuropathol Commun. 2023 Aug 31;11(1):141. doi: 10.1186/s40478-023-01631-9.
Acta Neuropathol Commun. 2023.
PMID: 37653534
Free PMC article.
We describe four MV2 histotypes: 2C, with cortical (C) coarse pathology; 2K, with kuru (K) plaque deposits; 2C-K, with co-existing C and K histotypic features; and the novel histotype 2C-PL that mimics 2C in the cerebral cortex and cerebellum, but exhibits plaque-like …
We describe four MV2 histotypes: 2C, with cortical (C) coarse pathology; 2K, with kuru (K) plaque deposits; 2C-K, with co-existing C and K h …