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Year Number of Results
1984 1
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1991 1
1992 2
1993 3
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1999 1
2001 3
2003 1
2005 2
2006 1
2007 1
2008 1
2009 1
2010 3
2011 1
2012 2
2013 1
2014 3
2015 2
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38 results

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Page 1
Heparin induced thrombocytopenia: diagnosis and management.
Alaraj A, Wallace A, Tesoro E, Ruland S, Amin-Hanjani S, Charbel FT, Aletich V. Alaraj A, et al. J Neurointerv Surg. 2010 Dec;2(4):371-8. doi: 10.1136/jnis.2010.002840. Epub 2010 Jul 23. J Neurointerv Surg. 2010. PMID: 21990651 Review.
Patients with HIT have a higher rate of thromboembolic complications, both arterial and venous, and with worse neurological outcomes at the time of discharge. Early diagnosis and heparin cessation are essential in the management of those patients. Both immediate and pro …
Patients with HIT have a higher rate of thromboembolic complications, both arterial and venous, and with worse neurological outcomes at the …
Management of acquired haemophilia A.
Tiede A, Scharf RE, Dobbelstein C, Werwitzke S. Tiede A, et al. Hamostaseologie. 2015;35(4):311-8. doi: 10.5482/HAMO-14-11-0064. Epub 2015 Jan 7. Hamostaseologie. 2015. PMID: 25564260 Review.
Acquired haemophilia A (AHA) is caused by autoantibody inhibitors of coagulation factor VIII (FVIII : C). Recent onset of bleeds and isolated prolongation of the activated partial thromboplastin time (aPTT) are characteristic features of the disorder. ...Patients sh …
Acquired haemophilia A (AHA) is caused by autoantibody inhibitors of coagulation factor VIII (FVIII : C). Recent onset of bleeds and isolate …
Drug Treatment of Venous Thromboembolism in the Elderly.
Boey JP, Gallus A. Boey JP, et al. Drugs Aging. 2016 Jul;33(7):475-90. doi: 10.1007/s40266-016-0378-x. Drugs Aging. 2016. PMID: 27255713 Review.
Traditional treatment with a heparin (usually low molecular weight) followed by a vitamin K antagonist such as warfarin is effective but is often complicated, especially in the elderly. The direct-acting oral anticoagulants (DOACs), i.e. the thrombin inhibitor dabigatran a …
Traditional treatment with a heparin (usually low molecular weight) followed by a vitamin K antagonist such as warfarin is effective but is …
Diagnosis and management of acute obstetrical DIC.
Kobayashi T, Terao T, Maki M, Ikenoue T. Kobayashi T, et al. Semin Thromb Hemost. 2001;27(2):161-7. doi: 10.1055/s-2001-14076. Semin Thromb Hemost. 2001. PMID: 11372771 Review.
MANAGEMENT: (1) Control of the underlying disease: because prolongation of exposure to the triggering factors worsens DIC, it is important to eliminate the etiologic factors as rapidly as possible. ...Controlled multicenter trials showed a significant improvement not only …
MANAGEMENT: (1) Control of the underlying disease: because prolongation of exposure to the triggering factors worsens DIC, it is impo …
Management of bleeding in patients treated with direct oral anticoagulants.
Levi M. Levi M. Crit Care. 2016 Aug 20;20:249. doi: 10.1186/s13054-016-1413-3. Crit Care. 2016. PMID: 27543264 Free PMC article. Review.
For the anti-factor Xa agents (rivaroxaban, apixaban, and edoxaban) a number of studies have shown that the administration of prothrombin complex concentrate resulted in a correction of the prolonged prothrombin time and restored depressed thrombin generation …
For the anti-factor Xa agents (rivaroxaban, apixaban, and edoxaban) a number of studies have shown that the administration of prothrombin co …
Abnormalities of prothrombin: a review of the pathophysiology, diagnosis, and treatment.
Meeks SL, Abshire TC. Meeks SL, et al. Haemophilia. 2008 Nov;14(6):1159-63. doi: 10.1111/j.1365-2516.2008.01832.x. Haemophilia. 2008. PMID: 19141155 Review.
Both hypoprothrombinemia and dysprothrombinemia have been described. Low prothrombin activity typically prolongs both the activated partial thromboplastin time and prothrombin time. ...No purified prothrombin products are available for replacement therapy …
Both hypoprothrombinemia and dysprothrombinemia have been described. Low prothrombin activity typically prolongs both the activated p …
Thrombin and topical local anesthetic for postoperative pain management.
Haddock NT, Weinstein AL, Sinno S, Chiu DT. Haddock NT, et al. Ann Plast Surg. 2014 Jul;73(1):30-2. doi: 10.1097/SAP.0b013e31826cafae. Ann Plast Surg. 2014. PMID: 23241808
We tested the hypothesis that local anesthetic pain relief can be prolonged with the adjunct use of thrombin. METHODS: A prospective single-blinded clinical study was performed. ...There were 7 patients in each group, and patient demographics were similar between gr …
We tested the hypothesis that local anesthetic pain relief can be prolonged with the adjunct use of thrombin. METHODS: A prosp …
Emicizumab treatment and monitoring in a paediatric cohort: real-world data.
Barg AA, Livnat T, Budnik I, Avishai E, Brutman-Barazani T, Tamarin I, Bashari D, Misgav M, Kenet G. Barg AA, et al. Br J Haematol. 2020 Oct;191(2):282-290. doi: 10.1111/bjh.16964. Epub 2020 Jul 12. Br J Haematol. 2020. PMID: 32656767 Free article.
Bleeding, trauma, adverse events, and surgeries were documented during a median follow-up of 45 weeks. Emicizumab levels, activated partial thromboplastin time (aPTT) values, and thrombin generation were measured before and during therapy. ...Elevation in the …
Bleeding, trauma, adverse events, and surgeries were documented during a median follow-up of 45 weeks. Emicizumab levels, activated partial …
Clinical phenotype, laboratory features and genotype of 35 patients with heritable dysfibrinogenaemia.
Shapiro SE, Phillips E, Manning RA, Morse CV, Murden SL, Laffan MA, Mumford AD. Shapiro SE, et al. Br J Haematol. 2013 Jan;160(2):220-7. doi: 10.1111/bjh.12085. Epub 2012 Oct 15. Br J Haematol. 2013. PMID: 23061815 Free article.
All subject showed dry clot weight within or above laboratory reference interval (median 3.2 g/l; range 1.9-5.1), reduced Clauss fibrinogen (median 0.52 g/l; range 0.21-1.3), and prolonged thrombin (median 30.7 s; range 21.3-45.7) and reptilase (median 42.0 s …
All subject showed dry clot weight within or above laboratory reference interval (median 3.2 g/l; range 1.9-5.1), reduced Clauss fibrinogen …
An engineered activated factor V for the prevention and treatment of acute traumatic coagulopathy and bleeding in mice.
Joseph BC, Miyazawa BY, Esmon CT, Cohen MJ, von Drygalski A, Mosnier LO. Joseph BC, et al. Blood Adv. 2022 Feb 8;6(3):959-969. doi: 10.1182/bloodadvances.2021005257. Blood Adv. 2022. PMID: 34861695 Free PMC article.
First, ATC was induced by the combination of trauma and shock. ATC was characterized by activated partial thromboplastin time (APTT) prolongation and reductions of factor V (FV), factor VIII (FVIII), and fibrinogen but not factor II and factor X. Administration of s …
First, ATC was induced by the combination of trauma and shock. ATC was characterized by activated partial thromboplastin time (APTT) …
38 results