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1999 | 1 |
2019 | 1 |
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The Architecture of Circulating Immune Cells Is Dysregulated in People Living With HIV on Long Term Antiretroviral Treatment and Relates With Markers of the HIV-1 Reservoir, Cytomegalovirus, and Microbial Translocation.
Front Immunol. 2021 Apr 19;12:661990. doi: 10.3389/fimmu.2021.661990. eCollection 2021.
Front Immunol. 2021.
PMID: 33953724
Free PMC article.
Long-term changes in the immune system of successfully treated people living with HIV (PLHIV) remain incompletely understood. In this study, we assessed 108 white blood cell (WBC) populations in a cohort of 211 PLHIV on stable antiretroviral therapy and in 56 HIV-un …
Long-term changes in the immune system of successfully treated people living with HIV (PLHIV) remain incompletely understood. In this study, …
Direct-Acting Antiviral Treatment of HCV Infection Does Not Resolve the Dysfunction of Circulating CD8(+) T-Cells in Advanced Liver Disease.
Vranjkovic A, Deonarine F, Kaka S, Angel JB, Cooper CL, Crawley AM.
Vranjkovic A, et al.
Front Immunol. 2019 Aug 13;10:1926. doi: 10.3389/fimmu.2019.01926. eCollection 2019.
Front Immunol. 2019.
PMID: 31456810
Free PMC article.
In HCV(+)(F4) individuals, nearly all CD8(+) T-cell subsets had an elevated proportion of perforin(+) cells while naive cells had increased proportions of IFN-gamma(+) and CD107(+) cells. These exaggerated CD8(+) T-cell activities were not resolved when evaluated 24 weeks …
In HCV(+)(F4) individuals, nearly all CD8(+) T-cell subsets had an elevated proportion of perforin(+) cells while naive cells had increased …
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Polyclonal anti-tumor necrosis factor-alpha Fab used as an ancillary treatment for severe malaria.
Looareesuwan S, Sjostrom L, Krudsood S, Wilairatana P, Porter RS, Hills F, Warrell DA.
Looareesuwan S, et al.
Am J Trop Med Hyg. 1999 Jul;61(1):26-33. doi: 10.4269/ajtmh.1999.61.26.
Am J Trop Med Hyg. 1999.
PMID: 10432050
On admission all patients had markedly elevated levels of TNF-alpha (85-1,532 ng/L) and interleukin-6 (IL-6) (30-27,500 ng/L). Also, 86% had elevated interferon-gamma (IFN-gamma) levels, 75% had increased IL-2 levels, 36% had increased IL-8 levels, and 21% ha …
On admission all patients had markedly elevated levels of TNF-alpha (85-1,532 ng/L) and interleukin-6 (IL-6) (30-27,500 ng/L). Also, 86% had …
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