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Top 10 Differential Diagnoses for Desmoplastic Melanoma.
Fernandez-Flores A, Singh R, Cassarino DS. Fernandez-Flores A, et al. Head Neck Pathol. 2023 Mar;17(1):143-153. doi: 10.1007/s12105-023-01536-y. Epub 2023 Mar 16. Head Neck Pathol. 2023. PMID: 36928737 Free PMC article. Review.
BACKGROUND: Desmoplastic melanoma is a rare subtype of melanoma mainly appearing on sun-exposed skin. Clinically, it is many times non-pigmented and therefore the diagnosis is often not suspected. ...The histopathological pattern can be many times deceptive, mimicking a sc …
BACKGROUND: Desmoplastic melanoma is a rare subtype of melanoma mainly appearing on sun-exposed skin. Clinically, it is many times no …
Treatment Options for Multinucleate Cell Angiohistiocytoma: A Case Series and Review of the Literature.
Taibo A, Padin CP, Losada JDP, Fonseca E. Taibo A, et al. J Cutan Med Surg. 2023 May-Jun;27(3):219-225. doi: 10.1177/12034754231163539. Epub 2023 Mar 16. J Cutan Med Surg. 2023. PMID: 36927096 Review.
OBJECTIVES: The aim of the present study is to review the therapeutical approaches for MCAH in the literature and to report the results of the different therapies followed at our institution. METHODS: A literature review was conducted including all MCAH published ca …
OBJECTIVES: The aim of the present study is to review the therapeutical approaches for MCAH in the literature and to report the resul …
Dermatofibrosarcoma protuberans in children: an update on the diagnosis and treatment.
Kornik RI, Muchard LK, Teng JM. Kornik RI, et al. Pediatr Dermatol. 2012 Nov-Dec;29(6):707-13. doi: 10.1111/j.1525-1470.2012.01767.x. Epub 2012 Jul 11. Pediatr Dermatol. 2012. PMID: 22780227 Review.
Dermatofibrosarcoma protuberans (DFSP) is a fibrohistiocytic tumor of low grade malignant potential. Although rare, pediatric cases pose a particular challenge in diagnosis and management. ...While surgery with wide local excision or Mohs micrographic surgery is the mainst …
Dermatofibrosarcoma protuberans (DFSP) is a fibrohistiocytic tumor of low grade malignant potential. Although rare, pediatric cases p …
Diagnostic and Management Considerations in Pediatric Dermatofibrosarcoma Protuberans.
Reilly DJ, Loo YL, Alexander WM, Wilks DJ, MacGregor D, Coombs CJ. Reilly DJ, et al. Ann Plast Surg. 2022 Mar 1;88(3):319-322. doi: 10.1097/SAP.0000000000002970. Ann Plast Surg. 2022. PMID: 34387577
BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a rare fibrohistiocytic tumor of dermal origin. Six percent of all cases present in children, with a childhood incidence of 1 per million. ...
BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a rare fibrohistiocytic tumor of dermal origin. Six percent of all cases presen …
Multinucleate cell angiohistiocytoma: A clinicopathologic study of 62 cases and proposed diagnostic criteria.
Roy SF, Dong D, Myung P, McNiff JM. Roy SF, et al. J Cutan Pathol. 2019 Aug;46(8):563-569. doi: 10.1111/cup.13463. Epub 2019 Apr 23. J Cutan Pathol. 2019. PMID: 30927287
BACKGROUND: Multinucleate cell angiohistiocytoma (MCAH) is an uncommon and likely underdiagnosed entity that is thought to be of vascular and fibrohistiocytic origin. METHODS: We retrospectively reviewed all cases diagnosed as MCAH at the Yale Medicine Dermatopathology lab …
BACKGROUND: Multinucleate cell angiohistiocytoma (MCAH) is an uncommon and likely underdiagnosed entity that is thought to be of vascular an …
Atypical fibroxanthoma: Systematic review and meta-analysis of treatment with Mohs micrographic surgery or excision.
Tolkachjov SN, Kelley BF, Alahdab F, Erwin PJ, Brewer JD. Tolkachjov SN, et al. J Am Acad Dermatol. 2018 Nov;79(5):929-934.e6. doi: 10.1016/j.jaad.2018.06.048. Epub 2018 Jul 5. J Am Acad Dermatol. 2018. PMID: 29981390
BACKGROUND: Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optima …
BACKGROUND: Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic p …
Soft tissue sarcomas of childhood: the differential diagnostic dilemma of the small blue cell.
Dehner LP. Dehner LP. Natl Cancer Inst Monogr. 1981 Apr;(56):43-59. Natl Cancer Inst Monogr. 1981. PMID: 6272117 Review.
In its histologic features, embryonal rhabdomyosarcoma (RMS), the prototype of malignant soft tissue tumors in childhood, summarizes the problems associated with the diagnosis of this entire group of neoplasms. Many of the tumors that do not fulfill the criteria for RMS ha …
In its histologic features, embryonal rhabdomyosarcoma (RMS), the prototype of malignant soft tissue tumors in childhood, summarizes the pro …
Antibodies to intermediate filament proteins. The differential diagnosis of cutaneous tumors.
Miettinen M, Lehto VP, Virtanen I. Miettinen M, et al. Arch Dermatol. 1985 Jun;121(6):736-41. Arch Dermatol. 1985. PMID: 2408582
Epithelial tumors, such as basocellular and squamous cell carcinomas, cutaneous adnexal tumors, and metastatic carcinomas showed keratin positivity in a varying number of tumor cells with two keratin antibodies with different specificities. Neoplastic cells of fibrohistiocytic …
Epithelial tumors, such as basocellular and squamous cell carcinomas, cutaneous adnexal tumors, and metastatic carcinomas showed keratin pos …
High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors.
Hanly AJ, Jordà M, Elgart GW, Badiavas E, Nassiri M, Nadji M. Hanly AJ, et al. Arch Pathol Lab Med. 2006 Jun;130(6):831-4. doi: 10.5858/2006-130-831-HPAEDR. Arch Pathol Lab Med. 2006. PMID: 16740036 Free article.
CONTEXT: Dermatofibroma is a benign fibrohistiocytic tumor composed of a mixture of fibroblastic and histiocytic cells. ...OBJECTIVE: To find an immunohistochemical marker or markers that differentiate between fibrohistiocytic lesions of skin. DESIGN: We eval …
CONTEXT: Dermatofibroma is a benign fibrohistiocytic tumor composed of a mixture of fibroblastic and histiocytic cells. ...OBJECTIVE: …
Atypical fibroxanthoma. A study of 14 cases emphasizing the presence of Langerhans' histiocytes with implications for differential diagnosis by antibody panels.
Ricci A Jr, Cartun RW, Zakowski MF. Ricci A Jr, et al. Am J Surg Pathol. 1988 Aug;12(8):591-8. Am J Surg Pathol. 1988. PMID: 3400790
Our findings are consistent with the current notion that these tumors are "fibrohistiocytic". However, in 11 of 12 cases studied, a subpopulation of cells with features of Langerhans' histiocytes (LH) was also identified. ...Awareness of their presence as an expected and s …
Our findings are consistent with the current notion that these tumors are "fibrohistiocytic". However, in 11 of 12 cases studied, a s …
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