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1991 1
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STING expression and response to treatment with STING ligands in premalignant and malignant disease.
Baird JR, Feng Z, Xiao HD, Friedman D, Cottam B, Fox BA, Kramer G, Leidner RS, Bell RB, Young KH, Crittenden MR, Gough MJ. Baird JR, et al. PLoS One. 2017 Nov 14;12(11):e0187532. doi: 10.1371/journal.pone.0187532. eCollection 2017. PLoS One. 2017. PMID: 29135982 Free PMC article.
We aimed to investigate STING ligands as a novel treatment for papilloma. We tested therapies in a spontaneous mouse model of papilloma of the face and anogenital region that histologically resembles human HPV-associated papilloma. We demonstrate that …
We aimed to investigate STING ligands as a novel treatment for papilloma. We tested therapies in a spontaneous mouse model of …
Longitudinal Erythronychia: Retrospective Single-Center Study Evaluating Differential Diagnosis and the Likelihood of Malignancy.
Jellinek NJ, Lipner SR. Jellinek NJ, et al. Dermatol Surg. 2016 Mar;42(3):310-9. doi: 10.1097/DSS.0000000000000594. Dermatol Surg. 2016. PMID: 26918968
Clinicopathologic correlation is required to make the diagnosis in many cases. Malignancy is uncommon, but not rare, with squamous cell carcinoma in situ representing the most common malignancy....
Clinicopathologic correlation is required to make the diagnosis in many cases. Malignancy is uncommon, but not rare, with squamous
Management of ungual warts.
Herschthal J, McLeod MP, Zaiac M. Herschthal J, et al. Dermatol Ther. 2012 Nov-Dec;25(6):545-50. doi: 10.1111/j.1529-8019.2012.01509.x. Dermatol Ther. 2012. PMID: 23210753
Warts are the most common nail tumor generally caused by human papilloma virus (HPV) 1, 2, 4, 27, and 57. HPV 16 and 18 are associated with malignant transformation to squamous cell carcinoma, while HPV 2 and 7 are associated with "butcher's warts." Current t …
Warts are the most common nail tumor generally caused by human papilloma virus (HPV) 1, 2, 4, 27, and 57. HPV 16 and 18 are associate …
Pathophysiology, Histopathology, and Differential Diagnostics of Basal Cell Carcinoma and Cutaneous Squamous Cell Carcinoma-An Update from the Pathologist's Point of View.
Cocuz IG, Popelea MC, Niculescu R, Manea A, Sabău AH, Tinca AC, Szoke AR, Budin CE, Stoian A, Morariu SH, Cotoi TC, Cocuz ME, Cotoi OS. Cocuz IG, et al. Int J Mol Sci. 2024 Feb 13;25(4):2220. doi: 10.3390/ijms25042220. Int J Mol Sci. 2024. PMID: 38396897 Free PMC article.
Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the most frequently occurring non-melanocytic skin cancers. ...We analyzed the histopathological appearances and immunohistochemical profiles of BCC and cSCC in comparison with …
Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the most frequently occurring non-melanocyt …
Prognosis and treatment of advanced squamous cell carcinoma secondary to epidermodysplasia verruciformis: a worldwide analysis of 11 patients.
Kaspar TA, Wagner RF Jr, Jablonska S, Niimura M, Tyring SK. Kaspar TA, et al. J Dermatol Surg Oncol. 1991 Mar;17(3):237-40. doi: 10.1111/j.1524-4725.1991.tb03637.x. J Dermatol Surg Oncol. 1991. PMID: 2005244
Data were collected from three medical centers in the USA, Poland, and Japan regarding 11 patients with advanced squamous cell carcinoma (SCC) secondary to epidermodysplasia verruciformis (EV). ...Mean patient survival time following metastases was 1.7 years (N = 2) …
Data were collected from three medical centers in the USA, Poland, and Japan regarding 11 patients with advanced squamous cell
Advances in photodynamic therapy for the treatment of head and neck cancers.
Biel M. Biel M. Lasers Surg Med. 2006 Jun;38(5):349-55. doi: 10.1002/lsm.20368. Lasers Surg Med. 2006. PMID: 16788923
Photodynamic therapy (PDT) is an FDA-approved minimally invasive medical treatment modality that utilizes light in the presence of oxygen to activate photosensitizing agents that are relatively selectively concentrated in abnormal or neoplastic cells resulting in …
Photodynamic therapy (PDT) is an FDA-approved minimally invasive medical treatment modality that utilizes light in the presence of ox …
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions.
Wolfgang GH, Shibata R, Wang J, Ray AS, Wu S, Doerrfler E, Reiser H, Lee WA, Birkus G, Christensen ND, Andrei G, Snoeck R. Wolfgang GH, et al. Antimicrob Agents Chemother. 2009 Jul;53(7):2777-84. doi: 10.1128/AAC.00103-09. Epub 2009 Apr 27. Antimicrob Agents Chemother. 2009. PMID: 19398642 Free PMC article.
GS-9191 is a novel double prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine (PMEG) designed as a topical agent to permeate skin and be metabolized to the active nucleoside triphosphate analog in the epithelial layer. ...In contrast, GS-9191 was ge …
GS-9191 is a novel double prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine (PMEG) designed as a topical agent to permeat …
The prevalence of human papillomavirus genotypes in nonmelanoma skin cancers of nonimmunosuppressed individuals identifies high-risk genital types as possible risk factors.
Iftner A, Klug SJ, Garbe C, Blum A, Stancu A, Wilczynski SP, Iftner T. Iftner A, et al. Cancer Res. 2003 Nov 1;63(21):7515-9. Cancer Res. 2003. PMID: 14612553
A total of 390 patients with histologically confirmed diagnosis of warts (n = 209), solar keratosis or Bowen's disease (n = 91), squamous cell carcinoma (n = 72), or basal cell carcinoma (n = 18), as well as 106 control patients with normal skin was an …
A total of 390 patients with histologically confirmed diagnosis of warts (n = 209), solar keratosis or Bowen's disease (n = 91), squamous
Imiquimod 5% cream: a new treatment for Bowen's disease.
Mandekou-Lefaki I, Delli F, Koussidou-Eremondi T, Mourellou-Tsatsou O, Dionyssopoulos A. Mandekou-Lefaki I, et al. Int J Tissue React. 2005;27(1):31-8. Int J Tissue React. 2005. PMID: 15847103
Bowen's disease (BD) is a squamous cell carcinoma in situ. Recent studies suggest that human papilloma virus plays an important role in the development of BD. ...
Bowen's disease (BD) is a squamous cell carcinoma in situ. Recent studies suggest that human papilloma virus plays an i …