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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1955 1
1958 1
1962 1
1963 1
1966 5
1967 6
1968 1
1969 2
1970 12
1971 4
1972 2
1973 1
1974 2
1975 1
1976 4
1977 9
1978 7
1979 4
1980 5
1981 4
1982 6
1983 2
1984 5
1985 7
1986 7
1987 41
1988 129
1989 202
1990 1173
1991 1141
1992 1193
1993 1254
1994 1331
1995 1218
1996 1160
1997 1148
1998 1136
1999 1143
2000 1304
2001 1266
2002 1262
2003 1382
2004 1439
2005 1363
2006 1413
2007 1383
2008 1457
2009 1386
2010 1468
2011 1583
2012 1548
2013 1575
2014 2167
2015 2414
2016 2383
2017 2303
2018 2201
2019 2093
2020 2135
2021 2017
2022 1517
2023 1552
2024 561

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49,492 results

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Page 1
Domestic dog lineages reveal genetic drivers of behavioral diversification.
Dutrow EV, Serpell JA, Ostrander EA. Dutrow EV, et al. Cell. 2022 Dec 8;185(25):4737-4755.e18. doi: 10.1016/j.cell.2022.11.003. Cell. 2022. PMID: 36493753 Free PMC article.
We identify ten major canine genetic lineages and their behavioral correlates and show that breed diversification is predominantly driven by non-coding regulatory variation. ...This work presents a scaffold for canine diversification that positions the domestic d …
We identify ten major canine genetic lineages and their behavioral correlates and show that breed diversification is predominantly dr …
Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M. Moin SM, et al. Immunity. 2022 Dec 13;55(12):2405-2418.e7. doi: 10.1016/j.immuni.2022.10.015. Epub 2022 Nov 9. Immunity. 2022. PMID: 36356572 Free PMC article.
Here, we showed that the co-immunization of two HA stem immunogens derived from group 1 and 2 influenza A viruses elicits cross-group protective immunity and neutralizing antibody responses in mice, ferrets, and nonhuman primates (NHPs). Immunized mice …
Here, we showed that the co-immunization of two HA stem immunogens derived from group 1 and 2 influenza A viruses elicits cross-group protec …
Euthanasia.
Donovan J, Brown P. Donovan J, et al. Curr Protoc Immunol. 2006 Jul;Chapter 1:1.8.1-1.8.4. doi: 10.1002/0471142735.im0108s73. Curr Protoc Immunol. 2006. PMID: 18432966
Euthanasia of laboratory animals must be performed by trained personnel using appropriate techniques, equipment, and reagents in order to effect a death that is humane and satisfies research requirements. ...This unit offers protocols for euthanasia employing carbon dioxid …
Euthanasia of laboratory animals must be performed by trained personnel using appropriate techniques, equipment, and reagents in orde …
Atypical Ebola Virus Disease in a Rhesus Macaque.
Marzi A, Hanley PW, Furuyama W, Haddock E, Martens CA, Scott DP, Feldmann H. Marzi A, et al. J Infect Dis. 2023 Nov 13;228(Suppl 7):S617-S625. doi: 10.1093/infdis/jiad283. J Infect Dis. 2023. PMID: 37477943 Free PMC article.
Symptoms associated with this syndrome include uveitis and neurological manifestations. In 1 of our EBOV-Makona nonhuman primate (NHP) studies, 1 NHP was euthanized on day 28 after infection having completely recovered from the acute disease. During convalesc …
Symptoms associated with this syndrome include uveitis and neurological manifestations. In 1 of our EBOV-Makona nonhuman primate ( …
Canine Cancer Genomics: Lessons for Canine and Human Health.
Ostrander EA, Dreger DL, Evans JM. Ostrander EA, et al. Annu Rev Anim Biosci. 2019 Feb 15;7:449-472. doi: 10.1146/annurev-animal-030117-014523. Epub 2018 Nov 12. Annu Rev Anim Biosci. 2019. PMID: 30418802 Review.
Each has undergone strong artificial selection, in which dog fanciers selected for many traits, including body size, fur type, color, skull shape, and behavior, to create novel breeds. ...We and others have taken advantage of this to identify genes for a large number of …
Each has undergone strong artificial selection, in which dog fanciers selected for many traits, including body size, fur type, color, …
Microbiome Studies in Non-human Primates.
Brenchley JM, Ortiz AM. Brenchley JM, et al. Curr HIV/AIDS Rep. 2021 Dec;18(6):527-537. doi: 10.1007/s11904-021-00584-9. Epub 2021 Nov 4. Curr HIV/AIDS Rep. 2021. PMID: 34735686 Free PMC article. Review.
PURPOSE OF REVIEW: Observations of differing bacterial, intestinal microbiomes in people living with HIV have propelled interest in contributions of the microbiome to HIV disease. Non-human primate (NHP) models of HIV infection provide a controlled setting for asses …
PURPOSE OF REVIEW: Observations of differing bacterial, intestinal microbiomes in people living with HIV have propelled interest in contribu …
Animal Models of Ebolavirus Infection.
St Claire MC, Ragland DR, Bollinger L, Jahrling PB. St Claire MC, et al. Comp Med. 2017 Jun 1;67(3):253-262. Comp Med. 2017. PMID: 28662754 Free PMC article. Review.
Ebola virus is classified as a BSL4 pathogen and Category A agent, for which the United States government requires preparedness in case of bioterrorism. Rodents, such as Syrian golden hamsters (Mesocricetus auratus), mice (Mus musculus), and guinea pigs …
Ebola virus is classified as a BSL4 pathogen and Category A agent, for which the United States government requires preparedness in case of b …
The canine genome.
Ostrander EA, Wayne RK. Ostrander EA, et al. Genome Res. 2005 Dec;15(12):1706-16. doi: 10.1101/gr.3736605. Genome Res. 2005. PMID: 16339369 Free article. Review.
The dog has emerged as a premier species for the study of morphology, behavior, and disease. The recent availability of a high-quality draft sequence lifts the dog system to a new threshold. We provide a primer to use the dog genome by first focusing on its e …
The dog has emerged as a premier species for the study of morphology, behavior, and disease. The recent availability of a high-qualit …
Blood collection.
Donovan J, Brown P. Donovan J, et al. Curr Protoc Immunol. 2006 Jul;Chapter 1:1.7.1-1.7.9. doi: 10.1002/0471142735.im0107s73. Curr Protoc Immunol. 2006. PMID: 18432965
The protocols offered in this unit describe collection of blood from the orbital sinus or plexus of the mouse, rat, or hamster. With appropriate techniques, small amounts of blood can be obtained with little ill effect on the animal. Collection from th …
The protocols offered in this unit describe collection of blood from the orbital sinus or plexus of the mouse, rat, or hams …
Animal identification.
Donovan J, Brown P. Donovan J, et al. Curr Protoc Immunol. 2006 Jul;Chapter 1:1.5.1-1.5.4. doi: 10.1002/0471142735.im0105s73. Curr Protoc Immunol. 2006. PMID: 18432963
Proper identification of animals is crucial in research, whether the animals are being used as experimental subjects, for breeding purposes, or as a source for tissues, cells, or fluids. This unit provides specific protocols for the ear punch (notch) and ear tag met …
Proper identification of animals is crucial in research, whether the animals are being used as experimental subjects, for bree …
49,492 results
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