High Volume PRP Therapy.
Ortop Traumatol Rehabil. 2022.
PMID: 35297377
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High Volume PRP Therapy.
Ortop Traumatol Rehabil. 2022 Feb 28;24(1):43-60. doi: 10.5604/01.3001.0015.7806.
Ortop Traumatol Rehabil. 2022.
PMID: 35297377
The aim of the study was to retrospectively evaluate the effectiveness of high-volume PRP therapy with the Angel system (Arthrex) in our patients. MATERIAL AND METHODS: A total of 400 therapies were performed on 299 patients. ...High …
The aim of the study was to retrospectively evaluate the effectiveness of high-volume PRP therapy with the Angel …
Effect of Intra-articular Platelet-Rich Plasma vs Placebo Injection on Pain and Medial Tibial Cartilage Volume in Patients With Knee Osteoarthritis: The RESTORE Randomized Clinical Trial.
JAMA. 2021 Nov 23;326(20):2021-2030. doi: 10.1001/jama.2021.19415.
JAMA. 2021.
PMID: 34812863
Free PMC article.
Clinical Trial.
IMPORTANCE: Most clinical guidelines do not recommend platelet-rich plasma (PRP) for knee osteoarthritis (OA) because of lack of high-quality evidence on efficacy for symptoms and joint structure, but the guidelines emphasize the need for rigorous studies. Despite t …
IMPORTANCE: Most clinical guidelines do not recommend platelet-rich plasma (PRP) for knee osteoarthritis (OA) because of lack of h …
Surgical techniques for the removal of mandibular wisdom teeth.
Cochrane Database Syst Rev. 2020 Jul 26;7(7):CD004345. doi: 10.1002/14651858.CD004345.pub3.
Cochrane Database Syst Rev. 2020.
PMID: 32712962
Free PMC article.
We assessed 33 of the studies (53%) as being at high risk of bias and 29 as unclear. We report results for our primary outcomes below. ...There is insufficient evidence to determine whether there is any difference in alveolar osteitis according to irrigation method (mechan …
We assessed 33 of the studies (53%) as being at high risk of bias and 29 as unclear. We report results for our primary outcomes below …
Profound Properties of Protein-Rich, Platelet-Rich Plasma Matrices as Novel, Multi-Purpose Biological Platforms in Tissue Repair, Regeneration, and Wound Healing.
Int J Mol Sci. 2024 Jul 19;25(14):7914. doi: 10.3390/ijms25147914.
Int J Mol Sci. 2024.
PMID: 39063156
Free PMC article.
Review.
Consequently, a viable and viscous protein concentrate of functional total proteins, like fibrinogen, albumin, and alpha-2-macroglobulin is created. Consolidating a small volume of high platelet concentrate with a small volume of highly concentrated protein-r …
Consequently, a viable and viscous protein concentrate of functional total proteins, like fibrinogen, albumin, and alpha-2-macroglobulin is …
The Efficacy of Platelet-Rich Plasma on Tendon and Ligament Healing: A Systematic Review and Meta-analysis With Bias Assessment.
Am J Sports Med. 2018 Jul;46(8):2020-2032. doi: 10.1177/0363546517743746. Epub 2017 Dec 21.
Am J Sports Med. 2018.
PMID: 29268037
Free PMC article.
BACKGROUND: There has been a surge in high-level studies investigating platelet-rich plasma (PRP) for tendon and ligament injuries. ...Platelet and leukocyte count, injection volume, kit used, participant age/sex, comparator, and activating agent used were re …
BACKGROUND: There has been a surge in high-level studies investigating platelet-rich plasma (PRP) for tendon and ligament inju …
The Meniscus: Basic Science and Therapeutic Approaches.
J Clin Med. 2025 Mar 16;14(6):2020. doi: 10.3390/jcm14062020.
J Clin Med. 2025.
PMID: 40142829
Free PMC article.
Review.
Blood supply is a crucial factor in assessing healing potential. Knee cartilage volume loss and its modification often result from meniscal damage or excision, leading to osteoarthritis. ...It provides a comprehensive evaluation of tear stability and progression risk. Addi …
Blood supply is a crucial factor in assessing healing potential. Knee cartilage volume loss and its modification often result from me …
High-volume injections in Achilles tendinopathy: a systematic review.
Br Med Bull. 2024 Dec 12;152(1):35-47. doi: 10.1093/bmb/ldae015.
Br Med Bull. 2024.
PMID: 39496560
Free article.
INTRODUCTION: Achilles tendinopathy (AT) is common, particularly in runners. High-volume injections (HVIs) may be beneficial in the management of AT compared to other conservative management options, including exercise regimens, platelet-rich plasma (PRP) inj …
INTRODUCTION: Achilles tendinopathy (AT) is common, particularly in runners. High-volume injections (HVIs) may be beneficial i …
Long term improvement of knee osteoarthritis after injection of single high/very high volume of very pure PRP: A retrospective analysis of patients optimally managed in dedicated centers.
Regen Ther. 2024 Jan 3;25:203-212. doi: 10.1016/j.reth.2023.12.006. eCollection 2024 Mar.
Regen Ther. 2024.
PMID: 38234679
Free PMC article.
We also investigated the potential contributing factors including patient's phenotype and PRP characteristics. METHODS: Patients with symptomatic KOA and that failed first-line therapy received a single injection of a qualified PRP prepared using medical devi …
We also investigated the potential contributing factors including patient's phenotype and PRP characteristics. METHODS: Patients with …
Single Injection of High Volume of Autologous Pure PRP Provides a Significant Improvement in Knee Osteoarthritis: A Prospective Routine Care Study.
Int J Mol Sci. 2019 Mar 15;20(6):1327. doi: 10.3390/ijms20061327.
Int J Mol Sci. 2019.
PMID: 30884774
Free PMC article.
The objective was to recover 50% of responders three months after the procedure using OMERACT-OARSI criteria. RESULTS: A single administration of high volume pure PRP provided significant clinical benefit for 84.2% of the responders, three months after the pr …
The objective was to recover 50% of responders three months after the procedure using OMERACT-OARSI criteria. RESULTS: A single administrati …
Musculoskeletal Therapies: Musculoskeletal Injection Therapy.
FP Essent. 2018 Jul;470:21-26.
FP Essent. 2018.
PMID: 29963845
Review.
Physicians should understand the disease pathophysiology and evidence supporting available injections when determining appropriate therapy. These therapies include corticosteroid injections (CSIs), hyaluronic acid (HA) injections, hypertonic dextrose prolotherapy, p …
Physicians should understand the disease pathophysiology and evidence supporting available injections when determining appropriate therap …
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