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Treatment of congenital fibrinogen deficiency: overview and recent findings.
Tziomalos K, Vakalopoulou S, Perifanis V, Garipidou V. Tziomalos K, et al. Vasc Health Risk Manag. 2009;5:843-8. doi: 10.2147/vhrm.s5305. Epub 2009 Oct 12. Vasc Health Risk Manag. 2009. PMID: 19851522 Free PMC article. Review.
We review the management of afibrinogenemia. Replacement therapy is the mainstay of treatment of bleeding episodes in these patients and plasma-derived fibrinogen concentrate is the agent of choice. ...The development of new tests to identify higher risk patients an …
We review the management of afibrinogenemia. Replacement therapy is the mainstay of treatment of bleeding episodes in these patients …
Epidemiology and treatment of congenital fibrinogen deficiency.
Peyvandi F. Peyvandi F. Thromb Res. 2012 Dec;130 Suppl 2:S7-11. doi: 10.1016/S0049-3848(13)70004-5. Thromb Res. 2012. PMID: 23439004
Congenital fibrinogen deficiency is a rare bleeding disorder, affecting either the quantity (afibrinogenemia, hypofibrinogenemia) or quality (dysfibrinogenemia) of circulating fibrinogen. ...Dysfibrinogenemia is associated with both spontaneous bleedin …
Congenital fibrinogen deficiency is a rare bleeding disorder, affecting either the quantity (afibrinogenemia, hypofibri …
Fibrinogen concentrate for treatment of bleeding and surgical prophylaxis in congenital fibrinogen deficiency patients.
Lissitchkov T, Madan B, Djambas Khayat C, Zozulya N, Ross C, Karimi M, Kavakli K, De Angulo GR, Almomen A, Subramanian K, D'Souza F, Viswabandya A, Hoorfar H, Schwartz BA, Solomon C, Knaub S, Peyvandi F. Lissitchkov T, et al. J Thromb Haemost. 2020 Apr;18(4):815-824. doi: 10.1111/jth.14727. Epub 2020 Jan 21. J Thromb Haemost. 2020. PMID: 31885190 Free PMC article.
BACKGROUND: Congenital fibrinogen deficiency is an ultra-rare disorder in which patients can experience severe and/or frequent bleeding episodes (BEs). ...There were no deaths, no severe allergic or hypersensitivity reactions, and no clinical evidence of neut …
BACKGROUND: Congenital fibrinogen deficiency is an ultra-rare disorder in which patients can experience severe and/or f …
Efficacy and safety of fibrinogen concentrate for on-demand treatment of bleeding and surgical prophylaxis in paediatric patients with congenital fibrinogen deficiency.
Djambas Khayat C, Lohade S, D'Souza F, Shamanur LG, Zekavat OR, Kruzhkova I, Schwartz B, Solomon C, Knaub S, Peyvandi F. Djambas Khayat C, et al. Haemophilia. 2021 Mar;27(2):283-292. doi: 10.1111/hae.14230. Epub 2020 Dec 16. Haemophilia. 2021. PMID: 33326665 Free PMC article.
BACKGROUND: Congenital fibrinogen deficiency (CFD) is a rare, inherited disorder affecting normal blood clotting function, where patients can experience severe and/or frequent bleeding episodes (BEs). Treatment with human fibrinogen concentrate (HFC) c …
BACKGROUND: Congenital fibrinogen deficiency (CFD) is a rare, inherited disorder affecting normal blood clotting functi …