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Treatment of dedifferentiated chordoma: a retrospective study from a large volume cancer center.
Nachwalter RN, Rothrock RJ, Katsoulakis E, Gounder MM, Boland PJ, Bilsky MH, Laufer I, Schmitt AM, Yamada Y, Higginson DS. Nachwalter RN, et al. J Neurooncol. 2019 Sep;144(2):369-376. doi: 10.1007/s11060-019-03239-3. Epub 2019 Jul 23. J Neurooncol. 2019. PMID: 31338785 Free PMC article.
OBJECTIVE: Dedifferentiated chordomas (DC) are genetically and clinically distinct from conventional chordomas (CC), exhibiting frequent SMARCB1 alterations and a more aggressive clinical course. ...CONCLUSION: DC patients exhibit significantly higher rates of both synchro …
OBJECTIVE: Dedifferentiated chordomas (DC) are genetically and clinically distinct from conventional chordomas (CC), exhibiting frequ …
Carbon ions therapy as single treatment in chordoma of the sacrum. Histologic and metabolic outcome studies.
Evangelisti G, Fiore MR, Bandiera S, Barbanti Brodano G, Terzi S, Girolami M, Pipola V, Righi A, Nanni C, Fanti S, Ghermandi R, Molinelli S, Orecchia R, Boriani S, Gasbarrini A. Evangelisti G, et al. Eur Rev Med Pharmacol Sci. 2019 May;23(9):4002-4009. doi: 10.26355/eurrev_201905_17830. Eur Rev Med Pharmacol Sci. 2019. PMID: 31115029 Free article.
RESULTS: All histological analysis but 2 reported signs of necrosis and of fibrosclerosis after CIRT. One of these 2 patients turned into a dedifferentiated chordoma. Radiological partial response (PR) was observed in 10 patients (56.3%) and stable disease (SD) in 5 …
RESULTS: All histological analysis but 2 reported signs of necrosis and of fibrosclerosis after CIRT. One of these 2 patients turned into a …