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Brincidofovir: A Novel Agent for the Treatment of Smallpox.
Huston J, Curtis S, Egelund EF. Huston J, et al. Ann Pharmacother. 2023 Oct;57(10):1198-1206. doi: 10.1177/10600280231151751. Epub 2023 Jan 23. Ann Pharmacother. 2023. PMID: 36688308 Review.
DATA SYNTHESIS: Two surrogate animal models were included in the Food and Drug Administration's (FDA) decision to approve brincidofovir: ectromelia virus in mice and rabbitpox in rabbits. Phases 2 and 3 studies established safety for approval. ...
DATA SYNTHESIS: Two surrogate animal models were included in the Food and Drug Administration's (FDA) decision to approve brincidofovir: …
Induction, treatment and prevention of eczema vaccinatum in atopic dermatitis mouse models.
Achdout H, Lustig S, Israely T, Erez N, Politi B, Tamir H, Israeli O, Waner T, Melamed S, Paran N. Achdout H, et al. Vaccine. 2017 Jul 24;35(33):4245-4254. doi: 10.1016/j.vaccine.2017.06.014. Epub 2017 Jun 20. Vaccine. 2017. PMID: 28625523
Unlike the severe manifestations of eczema vaccinatum in humans, current models present only mild symptoms that limits examination of potential therapeutics for eczema vaccinatum. The atopic dermatitis and eczema vaccinatum models we present here, are the first to simulate …
Unlike the severe manifestations of eczema vaccinatum in humans, current models present only mild symptoms that limits examination of potent …