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Advances in the Treatment of Hairy Cell Leukemia Variant.
Tran J, Gaulin C, Tallman MS. Tran J, et al. Curr Treat Options Oncol. 2022 Jan;23(1):99-116. doi: 10.1007/s11864-021-00927-z. Epub 2022 Feb 18. Curr Treat Options Oncol. 2022. PMID: 35178674 Review.
Hairy cell leukemia variant (HCL-V) is a rare B cell lymphoproliferative disorder with a clinical-pathological distinction from the classic form of hairy cell leukemia (HCL-C). ...To date, combination chemoimmunotherapies, s …
Hairy cell leukemia variant (HCL-V) is a rare B cell lymphoproliferative disorder with a clinical-patholo …
Management of hairy cell leukemia variant.
Robak T. Robak T. Leuk Lymphoma. 2011 Jun;52 Suppl 2:53-6. doi: 10.3109/10428194.2011.566392. Leuk Lymphoma. 2011. PMID: 21599606 Review.
Hairy cell leukemia variant (HCL-V) is now included in the World Health Organization (WHO) classification as a provisional entity and is no longer considered to be biologically related to classic HCL (HCL-C). ...In addition, HCL-V seems to be resistant …
Hairy cell leukemia variant (HCL-V) is now included in the World Health Organization (WHO) classification as a p …
Hairy cell leukemia diagnostic criteria and differential diagnosis.
Summers TA, Jaffe ES. Summers TA, et al. Leuk Lymphoma. 2011 Jun;52 Suppl 2(Suppl 2):6-10. doi: 10.3109/10428194.2011.565435. Epub 2011 Mar 21. Leuk Lymphoma. 2011. PMID: 21417827 Free PMC article. Review.
Hairy cell leukemia (HCL) is a disease with distinctive clinical findings, as well as a unique morphology and immunophenotype. ...This is paramount as current data indicate that hairy cell leukemia - variant and other splenic B- …
Hairy cell leukemia (HCL) is a disease with distinctive clinical findings, as well as a unique morphology and immunophe …
Hairy-cell leukemia variant: recent view on diagnosis, biology and treatment.
Robak T. Robak T. Cancer Treat Rev. 2011 Feb;37(1):3-10. doi: 10.1016/j.ctrv.2010.05.003. Epub 2010 Jun 16. Cancer Treat Rev. 2011. PMID: 20558005 Review.
Hairy-cell leukemia variant (HCl-V) is a district clinico-pathological entity with intermediate features between classical HCl (HCl-C) and B-cell prolymphocytic leukemia. ...In this review, the biology, diagnostic criteria, and current …
Hairy-cell leukemia variant (HCl-V) is a district clinico-pathological entity with intermediate features between …
Current treatment options in hairy cell leukemia and hairy cell leukemia variant.
Robak T. Robak T. Cancer Treat Rev. 2006 Aug;32(5):365-76. doi: 10.1016/j.ctrv.2006.04.010. Epub 2006 Jun 15. Cancer Treat Rev. 2006. PMID: 16781083 Review.
Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by splenomegaly, pancytopenia and circulating lymphocytes displaying prominent cytoplasmic projections. ...IFN-alpha may have a place in patients with very severe …
Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by splenomegaly, pancyt …
Purine nucleoside analogs plus rituximab are an effective treatment choice for hairy cell leukemia-variant.
Wang Y, Wang T, Yu Y, Wang Q, Yan Y, Li R, Sun Q, Xiong W, Lyu R, Yu Z, Liu W, Sui W, Huang W, Wang H, Li C, Wang J, Zou D, An G, Wang J, Qiu L, Yi S. Wang Y, et al. Ann Hematol. 2022 Jun;101(6):1201-1210. doi: 10.1007/s00277-022-04795-x. Epub 2022 Apr 18. Ann Hematol. 2022. PMID: 35437610
Both characteristics and optimal treatment strategy for hairy cell leukemia-variant (HCL-v) remain elusive due to its rarity. ...Immunophenotyping showed monoclonal B-cells positive for pan B-cell antigens and CD11c, weakly positive for CD103 an …
Both characteristics and optimal treatment strategy for hairy cell leukemia-variant (HCL-v) remain elusive due t …
Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias.
Robak T, Robak P. Robak T, et al. Curr Pharm Des. 2012;18(23):3373-88. doi: 10.2174/138161212801227005. Curr Pharm Des. 2012. PMID: 22591387 Review.
This review summarizes current knowledge on the mechanism of action and pharmacokinetic properties of older and new PNAs. Clinical activity and toxicity of PNAs, especially in hairy cell leukemia (HCL), hairy cell leukemia variant …
This review summarizes current knowledge on the mechanism of action and pharmacokinetic properties of older and new PNAs. Clinical activity …
Distinguishing hairy cell leukemia variant from hairy cell leukemia: development and validation of diagnostic criteria.
Shao H, Calvo KR, Grönborg M, Tembhare PR, Kreitman RJ, Stetler-Stevenson M, Yuan CM. Shao H, et al. Leuk Res. 2013 Apr;37(4):401-409. doi: 10.1016/j.leukres.2012.11.021. Epub 2013 Jan 22. Leuk Res. 2013. PMID: 23347903 Free PMC article.
Hairy cell leukemia (HCL) and hairy cell leukemia-variant (HCL-v) are rare diseases with overlapping clinico-pathological features. ...FCM distinguished HCL-v from HCL and SMZL based solely upon expression of four antigens (CD11c, …
Hairy cell leukemia (HCL) and hairy cell leukemia-variant (HCL-v) are rare diseases with ov …
Treatment of hairy cell leukemia-variant with cladribine.
Tetreault SA, Robbins BA, Saven A. Tetreault SA, et al. Leuk Lymphoma. 1999 Oct;35(3-4):347-54. doi: 10.3109/10428199909145739. Leuk Lymphoma. 1999. PMID: 10706459
Hairy cell leukemia-variant (HCL-V) is an extremely rare chronic B-cell lymphoproliferative disorder clinically and morphologically distinct from classic hairy cell leukemia (HCL). HCL-V is thought to represent a hybrid betw …
Hairy cell leukemia-variant (HCL-V) is an extremely rare chronic B-cell lymphoproliferative disorder clin …
Cladribine with immediate rituximab for the treatment of patients with variant hairy cell leukemia.
Kreitman RJ, Wilson W, Calvo KR, Arons E, Roth L, Sapolsky J, Zhou H, Raffeld M, Stetler-Stevenson M. Kreitman RJ, et al. Clin Cancer Res. 2013 Dec 15;19(24):6873-81. doi: 10.1158/1078-0432.CCR-13-1752. Epub 2013 Nov 25. Clin Cancer Res. 2013. PMID: 24277451 Free PMC article.
PURPOSE: In contrast with the classic form, variant hairy cell leukemia (HCLv) responds poorly to single-agent purine analogs, expresses unmutated BRAF, has shorter overall survival, and lacks effective standard therapy. ...
PURPOSE: In contrast with the classic form, variant hairy cell leukemia (HCLv) responds poorly to single-agent p …
13 results