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2019 1
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Emerging patient-specific treatment modalities in head and neck cancer - a systematic review.
Elicin O, Cihoric N, Vlaskou Badra E, Ozsahin M. Elicin O, et al. Expert Opin Investig Drugs. 2019 Apr;28(4):365-376. doi: 10.1080/13543784.2019.1582642. Epub 2019 Feb 26. Expert Opin Investig Drugs. 2019. PMID: 30760055
INTRODUCTION: Head and neck cancer (HNC) is an immunosuppressive disease that demonstrates heterogeneous molecular characteristics and features of tumor-host interaction. Beside radiotherapy and surgery, the current standard of care in systemic treatme …
INTRODUCTION: Head and neck cancer (HNC) is an immunosuppressive disease that demonstrates heterogeneous molecular characteristics and featu …
Integration of host-related signatures with cancer cell-derived predictors for the optimal management of anticancer chemotherapy.
Zitvogel L, Kepp O, Aymeric L, Ma Y, Locher C, Delahaye NF, André F, Kroemer G. Zitvogel L, et al. Cancer Res. 2010 Dec 1;70(23):9538-43. doi: 10.1158/0008-5472.CAN-10-1003. Epub 2010 Nov 23. Cancer Res. 2010. PMID: 21098713 Review.
Current cancer management aims to integrate molecular signatures into the design of personalized therapies. Recent advances in "omics" done on tumor specimens have led to the identification of factors that either recognize cancers of dismal prognosis or pinpoint "dr …
Current cancer management aims to integrate molecular signatures into the design of personalized therapies. Recent advances in "omics …
The biology of interleukin-2 efficacy in the treatment of patients with renal cell carcinoma.
Romo de Vivar Chavez A, de Vera ME, Liang X, Lotze MT. Romo de Vivar Chavez A, et al. Med Oncol. 2009;26 Suppl 1:3-12. doi: 10.1007/s12032-008-9162-z. Epub 2009 Jan 16. Med Oncol. 2009. PMID: 19148593 Review.
The IL-2 signaling pathway, its effects on immune cells, and its role in various independent mechanisms of tumor surveillance likely play a role but little substantive data defining a clear phenotype or genotype of IL-2 responders distinguishing them from nonresponders has …
The IL-2 signaling pathway, its effects on immune cells, and its role in various independent mechanisms of tumor surveillance likely …
Models of tumor-host interaction as competing populations: implications for tumor biology and treatment.
Gatenby RA. Gatenby RA. J Theor Biol. 1995 Oct 21;176(4):447-55. doi: 10.1006/jtbi.1995.0212. J Theor Biol. 1995. PMID: 8551743
It predicts general sequences of genetic changes necessary for tumor survival and invasion and demonstrates that apparently disparate properties found in different tumor models can be functionally equivalent. The paper proposes novel modes of therapy requirin …
It predicts general sequences of genetic changes necessary for tumor survival and invasion and demonstrates that apparently disparate …