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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 2
1994 1
1995 3
1997 6
1998 3
1999 4
2000 5
2001 3
2002 12
2003 13
2004 5
2005 16
2006 14
2007 24
2008 18
2009 23
2010 23
2011 28
2012 26
2013 34
2014 47
2015 58
2016 40
2017 49
2018 55
2019 68
2020 83
2021 113
2022 84
2023 91
2024 39

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862 results

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Page 1
Comprehensive Review on Alzheimer's Disease: Causes and Treatment.
Breijyeh Z, Karaman R. Breijyeh Z, et al. Molecules. 2020 Dec 8;25(24):5789. doi: 10.3390/molecules25245789. Molecules. 2020. PMID: 33302541 Free PMC article. Review.
This review discusses currently available drugs and future theories for the development of new therapies for AD, such as disease-modifying therapeutics (DMT), chaperones, and natural compounds....
This review discusses currently available drugs and future theories for the development of new therapies for AD, such as disease-modi …
Obesity and male infertility: Mechanisms and management.
Leisegang K, Sengupta P, Agarwal A, Henkel R. Leisegang K, et al. Andrologia. 2021 Feb;53(1):e13617. doi: 10.1111/and.13617. Epub 2020 May 12. Andrologia. 2021. PMID: 32399992 Review.
Complications of obesity include cardiovascular diseases, type 2 diabetes mellitus, malignancy (including prostatic cancer), neurodegeneration and accelerated ageing. In males, these further include erectile dysfunction, poor semen quality and subclinical prostatitis. ...
Complications of obesity include cardiovascular diseases, type 2 diabetes mellitus, malignancy (including prostatic cancer), neurodegener …
New Avenues for the Treatment of Huntington's Disease.
Kim A, Lalonde K, Truesdell A, Gomes Welter P, Brocardo PS, Rosenstock TR, Gil-Mohapel J. Kim A, et al. Int J Mol Sci. 2021 Aug 4;22(16):8363. doi: 10.3390/ijms22168363. Int J Mol Sci. 2021. PMID: 34445070 Free PMC article. Review.
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum and cortex. The first symptoms usually appear in mid-life and include cognitive deficits and …
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the HD gene. The disease is characterized by neuro …
Wolfram Syndrome: Diagnosis, Management, and Treatment.
Urano F. Urano F. Curr Diab Rep. 2016 Jan;16(1):6. doi: 10.1007/s11892-015-0702-6. Curr Diab Rep. 2016. PMID: 26742931 Free PMC article. Review.
Wolfram syndrome is a rare genetic disorder characterized by juvenile-onset diabetes mellitus, diabetes insipidus, optic nerve atrophy, hearing loss, and neurodegeneration. Although there are currently no effective treatments that can delay or reverse the progression of Wo …
Wolfram syndrome is a rare genetic disorder characterized by juvenile-onset diabetes mellitus, diabetes insipidus, optic nerve atrophy, hear …
Parkinson's disease: Mechanisms, translational models and management strategies.
Raza C, Anjum R, Shakeel NUA. Raza C, et al. Life Sci. 2019 Jun 1;226:77-90. doi: 10.1016/j.lfs.2019.03.057. Epub 2019 Apr 10. Life Sci. 2019. PMID: 30980848 Review.
Preclinical research may provide powerful tools to quest the potential therapeutic and neuroprotective compounds for dopaminergic neurons and hence possible cure for the Parkinson's disease....
Preclinical research may provide powerful tools to quest the potential therapeutic and neuroprotective compounds for dopaminergic neu …
Apathy after stroke: Diagnosis, mechanisms, consequences, and treatment.
Tay J, Morris RG, Markus HS. Tay J, et al. Int J Stroke. 2021 Jul;16(5):510-518. doi: 10.1177/1747493021990906. Epub 2021 Feb 4. Int J Stroke. 2021. PMID: 33527880 Free PMC article. Review.
Importantly, networks can be affected by physiological changes related to stroke, including the acute infarct but also diaschisis and neurodegeneration. Aside from neurobiological changes, apathy is also associated with other negative outcome measures such as functional di …
Importantly, networks can be affected by physiological changes related to stroke, including the acute infarct but also diaschisis and neu …
Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts.
McKee AC, Stein TD, Huber BR, Crary JF, Bieniek K, Dickson D, Alvarez VE, Cherry JD, Farrell K, Butler M, Uretsky M, Abdolmohammadi B, Alosco ML, Tripodis Y, Mez J, Daneshvar DH. McKee AC, et al. Acta Neuropathol. 2023 Apr;145(4):371-394. doi: 10.1007/s00401-023-02540-w. Epub 2023 Feb 10. Acta Neuropathol. 2023. PMID: 36759368 Free PMC article. Review.
Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention.
Mahaman YAR, Embaye KS, Huang F, Li L, Zhu F, Wang JZ, Liu R, Feng J, Wang X. Mahaman YAR, et al. Ageing Res Rev. 2022 Feb;74:101544. doi: 10.1016/j.arr.2021.101544. Epub 2021 Dec 18. Ageing Res Rev. 2022. PMID: 34933129 Review.
Its main histological hallmarks are the Abeta senile plaques and the P-tau neurofibrillary tangles, while clinically it is marked by a progressive cognitive decline that reflects the underlying synaptic loss and neurodegeneration. Many of the drug therapies targetin …
Its main histological hallmarks are the Abeta senile plaques and the P-tau neurofibrillary tangles, while clinically it is marked by a progr …
Targeting RIPK1 for the treatment of human diseases.
Degterev A, Ofengeim D, Yuan J. Degterev A, et al. Proc Natl Acad Sci U S A. 2019 May 14;116(20):9714-9722. doi: 10.1073/pnas.1901179116. Epub 2019 May 2. Proc Natl Acad Sci U S A. 2019. PMID: 31048504 Free PMC article. Review.
RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide range of human neurodegenerative, autoimmune, and inflammatory diseases. ...
RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide range of human neurodegenerative, autoimmune, …
862 results