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Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis.
Hawkes JE, Yan BY, Chan TC, Krueger JG. Hawkes JE, et al. J Immunol. 2018 Sep 15;201(6):1605-1613. doi: 10.4049/jimmunol.1800013. J Immunol. 2018. PMID: 30181299 Free PMC article. Review.
Psoriasis vulgaris is a common, heterogeneous, chronic inflammatory skin disease characterized by thickened, red, scaly plaques and systemic inflammation. ...Under the regulation of IL-23, T cells that produce high levels of IL-17 create a self-amplifying, feed-forw …
Psoriasis vulgaris is a common, heterogeneous, chronic inflammatory skin disease characterized by thickened, red, scaly plaque …
Differential diagnosis of benign and malignant male breast lesions in mammography.
Huang Y, Xiao Q, Sun Y, Li Q, Wang S, Gu Y. Huang Y, et al. Eur J Radiol. 2020 Nov;132:109339. doi: 10.1016/j.ejrad.2020.109339. Epub 2020 Oct 9. Eur J Radiol. 2020. PMID: 33080548
Imaging features included lesions location, lesion type, lesion density, lesion eccentricity, accompanying signs(calcification, nipple retraction, thickened skin and enlarged lymph nodes) were recorded and analysed by statistical methods. ...In the univariate logist …
Imaging features included lesions location, lesion type, lesion density, lesion eccentricity, accompanying signs(calcification, nipple retra …
Haematopoietic stem cell transplantation for the treatment of systemic sclerosis and other autoimmune disorders.
Tyndall A, Matucci-Cerinic M. Tyndall A, et al. Expert Opin Biol Ther. 2003 Oct;3(7):1041-9. doi: 10.1517/14712598.3.7.1041. Expert Opin Biol Ther. 2003. PMID: 14519069 Review.
The dose of such agents is limited by the inevitable toxicity on the bone marrow, but this threshold may be superseded by first removing the patient's own haematopoietic stem cells, followed by reconstitution of the marrow after high-dose myeloablative CY or other therapy. …
The dose of such agents is limited by the inevitable toxicity on the bone marrow, but this threshold may be superseded by first removing the …